Anna Malashicheva graduated from St. Petersburg State University, Faculty of Biology. In 1997, she had an internship at the University of Umea in Sweden. In 2001, Dr. Malashicheva successfully defended her Ph.D. thesis, titled “Investigation of the teratocarcinoma cell cycle checkpoints of a mouse under the damaging agents”. From 2001 to 2003, she interned in France, in Lyon, at the Ecole Normale Superieure de Lyon; from 2005 to 2006, she had an internship in Germany, at the Max Planck Institute. Since 2019, Anna Malashicheva has been working at the Institute of Cytology of the Russian Academy of Science as the Head of the Laboratory of regenerative biomedicine. The main direction of research is related to the study of molecular links that control the osteogenic differentiation of mesenchymal stem cells (MSC) of various origins including mechanisms of pathological ossification. It is obvious that one of the key roles in osteogenic differentiation is played by the interactions of the endothelium and the underlying cells, usually of mesenchymal origin. One of these areas of research is related to the search for specific molecular characteristics of endothelial cells, depending on which the endothelium is able to induce and enhance or suppress the osteogenic differentiation of mesenchymal stem cells, with the ultimate goal of creating approaches to obtain endothelial cells with desired osteoinductive/osteoprotective properties.
Institute of Cytology
Saint Petersburg, Sankt-Peterburg, Russia