Dr. Alessandro Terrinoni

Alessandro Terrinoni is currently an assistant professor of Medical Chemistry at the Department of Experimental Medicine, Universita di Roma “Tor Vergata”, and Laboratory of Medical Chemistry, Ospedale Policlinico Tor Vergata (PTV). He worked on the p53 family and in particular on p63 and p73, of which he identified the mechanism of cell death, the mechanisms of gene transactivation, the biochemical pathways of degradation, inhibitors of proteasomal degradation, and the physiological regulatory mechanisms. He also identified the biochemical mechanisms of death of keratinocytes in the skin in vitro and in vivo, and the genetic molecular basis of several genetic diseases, including: UNILATERAL palmoplantar verrucous nevus (OMIM 144200), Marie Unna Hereditary Hypotrichosis (OMIM 146550). His current scientific interest is the study of microRNA biology in normal physiological and pathological conditions, particularly on the identification of blood circulating miRs (c-miRNA) as molecular biomarkers of physical exercise and muscle differentiation.