Mining wastes, particularly in the form of waste rocks and tailings, can have major social and environmental impacts. There is a need for comprehensive long-term strategies for transforming the mining industry to move toward zero environmental footprint. “How can the mining industry create new economic value, minimise its social and environmental impacts and diminish liability from mining waste?” This would require cross-disciplinary skills, across the social, environmental, technical, legal, regulatory, and economic domains, to produce innovative solutions. The aim of this paper is to review the current knowledge across these domains and integrate them in a new approach for exploiting or “re-thinking” mining wastes. This approach includes five key areas of social dimensions, geoenvironmental aspects, geometallurgy specifications, economic drivers and legal implications for improved environmental outcomes, and circular economy aspirations, which are aligned with the 10 principles of the International Council on Mining and Metals (ICMM). Applying circular economy thinking to mining waste presents a major opportunity to reduce the liability and increase the value of waste materials arising from mining and processing operations.

Summary: The realization of regional synergies in industrial areas with intensive minerals processing provides a significant avenue toward sustainable resource processing. This article provides an overview of past and current synergy developments in two of Australia's major heavy industrial regions, Kwinana (Western Australia) and Gladstone (Queensland), and includes a comparative review and assessment of the drivers, barriers, and trigger events for regional synergies initiatives in both areas. Kwinana and Gladstone compare favorably with well‐known international examples in terms of the current level and maturity of industry involvement and collaboration and the commitment to further explore regional resource synergies. Kwinana stands out with regard to the number, diversity, complexity, and maturity of existing synergies. Gladstone is remarkable with regard to unusually large geographic boundaries and high dominance of one industry sector. Many diverse regional synergy opportunities still appear to exist in both industrial regions (particularly in Kwinana), mostly in three broad areas: water, energy, and inorganic by‐product reuse. To enhance the further development of new regional synergies, the Centre for Sustainable Resource Processing (CSRP), a joint initiative of Australian minerals processing companies, research providers, and government agencies, has undertaken several collaborative projects. These include research to facilitate the process of identifying and evaluating potential synergy opportunities and assistance for the industries with feasibility studies and implementation of selected synergy projects in both regions. The article also reports on the progress to date from this CSRP research.