A novel method for performing anatomical magnetic resonance imaging-functional (positron emission tomography or single photon emission computed tomography) image fusion is presented. The method merges specific feature information from input image signals of a single or multiple medical imaging modalities into a single fused image, while preserving more information and generating less distortion. The proposed method uses a local Laplacian filtering-based technique realized through a novel multi-scale system architecture. First, the input images are generated in a multi-scale image representation and are processed using local Laplacian filtering. Second, at each scale, the decomposed images are combined to produce fused approximate images using a local energy maximum scheme and produce the fused residual images using an information of interest-based scheme. Finally, a fused image is obtained using a reconstruction process that is analogous to that of conventional Laplacian pyramid transform. Experimental results computed using individual multi-scale analysis-based decomposition schemes or fusion rules clearly demonstrate the superiority of the proposed method through subjective observation as well as objective metrics. Furthermore, the proposed method can obtain better performance, compared with the state-of-the-art fusion methods.

Segmenting polyps from colonoscopy images is very important in clinical practice since it provides valuable information for colorectal cancer. However, polyp segmentation remains a challenging task as polyps have camouflage properties and vary greatly in size. Although many polyp segmentation methods have been recently proposed and produced remarkable results, most of them cannot yield stable results due to the lack of features with distinguishing properties and those with high-level semantic details. Therefore, we proposed a novel polyp segmentation framework called contrastive Transformer network (CTNet), with three key components of contrastive Transformer backbone, self-multiscale interaction module (SMIM), and collection information module (CIM), which has excellent learning and generalization abilities. The long-range dependence and highly structured feature map space obtained by CTNet through contrastive Transformer can effectively localize polyps with camouflage properties. CTNet benefits from the multiscale information and high-resolution feature maps with high-level semantic obtained by SMIM and CIM, respectively, and thus can obtain accurate segmentation results for polyps of different sizes. Without bells and whistles, CTNet yields significant gains of 2.3%, 3.7%, 3.7%, 18.2%, and 10.1% over classical method PraNet on Kvasir-SEG, CVC-ClinicDB, Endoscene, ETIS-LaribPolypDB, and CVC-ColonDB respectively. In addition, CTNet has advantages in camouflaged object detection and defect detection. The code is available at https://github.com/Fhujinwu/CTNet .

The convolutional neural network (CNN)-based multi-focus image fusion methods which learn the focus map from the source images have greatly enhanced fusion performance compared with the traditional methods. However, these methods have not yet reached a satisfactory fusion result, since the convolution operation pays too much attention on the local region and generating the focus map as a local classification (classify each pixel into focus or de-focus classes) problem. In this paper, a global-feature encoding U-Net (GEU-Net) is proposed for multi-focus image fusion. In the proposed GEU-Net, the U-Net network is employed for treating the generation of focus map as a global two-class segmentation task, which segments the focused and defocused regions from a global view. For improving the global feature encoding capabilities of U-Net, the global feature pyramid extraction module (GFPE) and global attention connection upsample module (GACU) are introduced to effectively extract and utilize the global semantic and edge information. The perceptual loss is added to the loss function, and a large-scale dataset is constructed for boosting the performance of GEU-Net. Experimental results show that the proposed GEU-Net can achieve superior fusion performance than some state-of-the-art methods in both human visual quality, objective assessment and network complexity.