Background: Skin diseases have been of major concern recently due to their association with the Human Immunodeficiency Virus and Acquired Immunity Deficiency Syndrome (HIV/AIDS). The study area (northern Maputaland) has the highest HIV infection rate in South Africa, which made them more prone to a wide range of skin conditions. Fungal infections due to the hot climate and overcrowding households are common in this area, as well as burn accidents due to the use of wood as the major fuel for cooking. It is known that the lay people in this area depend on medicinal plants for their primary health care. However no survey has been done in northern Maputaland to document the medicinal plants used to treat various skin disorder. Methods: Interviews were undertaken at 80 homesteads, using structured questionnaires. The focus was on plants used for dermatological conditions and information regarding vernacular plant names, plant parts used, preparation (independently and in various combinations) and application was collected. Results: A total of 87 lay people, both male (22%) and female (78%) were interviewed on their knowledge of medicinal plants used to treat disorders of the skin. Forty-seven plant species from 35 families were recorded in the present survey for the treatment of 11 different skin disorders including abscesses, acne, burns, boils, incisions, ringworm, rashes, shingles, sores, wounds and warts. When searching the most frequently used scientific databases (ScienceDirect, Scopus and Pubmed), nine plant species (Acacia burkei, Brachylaena discolor, Ozoroa engleri, Parinari capensis, subsp. capensis, Portulacaria afra, Sida pseudocordifolia, Solanum rigescens, Strychnos madagascariensis and Drimia delagoensis) were found to be recorded for the first time globally as a treatment for skin disorders. Fourteen plant combinations were used. Surprisingly, the application of enema’s was frequently mentioned. Conclusions: The preference of traditional medicine over allopathic medicine by most of the interviewees strengthens previous studies on the importance that traditional medicine can have in the primary health care system in this rural community. Studies to validate the potential of these plants independently and in their various combinations is underway to provide insight into the anti-infective role of each plant.

Ethnobotanical field studies in the Graaff-Reinet and Murraysburg regions (southeastern Karoo) have revealed a wealth of traditional knowledge on medicinal plants and their uses amongst elderly people of Khoi-San and Cape Dutch decent. The materia medica includes at least 86 species, most of which appear to be still in everyday use. The use of exotic plants (12 species) and similarities with the Xhosa healing culture show that the traditional system is dynamic and adaptive. Medicines to treat problems of the stomach, back, kidneys, bladder, as well as colds and other minor ailments have a high frequency. Mixtures of different plants are often used. An overview of the most important plants and their uses is presented, which shows several interesting records that have hitherto remained undocumented. These include new uses, new vernacular names and new medicinal plants (Abutilon sonneriatum, Aloe striata, Eberlanzia spinosa, Helichrysum pumilio, Osteospermum herbaceum, Pachypodium succulentum, Peliostomum cf. origanoides, Pentzia punctata, Rhigozum obovatum and Stapelia olivaea). New records of plants that are locally commonly used (e.g. H. pumilio and O. herbaceum) confirm that the medical ethnobotany of the Karoo is incompletely recorded

This ethnobotanical study on plants used for the treatment of sexually transmitted infections was undertaken to document the knowledge by lay people in a rural community in northern Maputaland, South Africa. The focus was on the medicinal plants which are growing in and around the immediate vicinity of the homesteads. Thirty three plant species were recorded as being used for the treatment of sexually transmitted infections such as gonorrhoea (drop or ugcusulu), external and internal sores caused by sexually transmitted infections, genital warts (cauliflower or umhluma) and syphilis. Nine plants (Bridelia cathartica subsp. cathartica, Cladostemon kirkii, Erianthemum dregei, Euphorbia hypericifolia, Ipomoea batatas, Krauseola mosambicina, Mimusops caffra, Opuntia stricta and Sarcophyte sanguinea subsp. sanguinea) were recorded for the first time in the literature world wide as a treatment for sexually transmitted infections. Five new vernacular names were documented for B. cathartica subsp. cathartica, Bryophyllum pinnatum, Clematis brachiata, E. hypericifolia and Pyrenacantha kaurabassana. The 33 plant species are used in 23 different combinations of two or more plants per herbal remedy. The three most frequently used plant species in the study area for the treatment of sexually transmitted infections are; Hypoxis hemerocallidia, Senecio serratuloides and Ranunculus multifidus. Roots are mostly prepared, as a decoction which is taken orally or used as an enema. All eighty of the interviewees preferred traditional medicine as the first therapeutic choice for treating sexually transmitted infections. The wide variety of plants that are used to treat sexually transmitted infections in this area emphasises the importance that medicinal plants can have in the primary health care system of the rural people in northern Maputaland (KwaZulu–Natal)