The present study aimed to characterize the nutraceutical properties and the antimicrobial effect of MoroccanSpirulina(Arthrospira platensis). The nutritional composition was evaluated, including water content, crude protein, total carbohydrates, lipids, phenolic composition, macro- and micromineral content, fiber content, and energy value. Then, the microbiological analysis and antioxidant activity were measured. The antimicrobial activity was evaluated using the minimum inhibitory concentration method on bacteria and fungi. MoroccanSpirulinacontained a large amount of protein (76.65 ± 0.15%), followed by carbohydrates (6.46 ± 0.32%), minerals (20.91 ± 0.88%), crude fiber (4.07 ± 1.42%), lipids (2.45 ± 0.82%), ash (14.56 ± 0.74), and twenty phenolic acids being identified and quantified. Moreover, flavonoid and phenolic contents were present at 15.60 ± 2.74 mg RE/g dw and 4.19 ± 0.21 mg GAE/g dw, respectively. Microbiological risk assessment indicated that this product is safe to be consumed as a human food product. The antioxidant activity was higher in the methanolic fraction (23 mg TE/g dw) (DPPH).

In Morocco, like in many developing countries, people usually tend to turn to unconventional therapies. An ethnophycological survey was realized to inventory seaweeds used in complementary Moroccan medicine. One hundred ninety-one (191) consumers and thirty-one (31) traditional healers were interviewed on seaweed food-related diseases using standardized questionnaires. The survey was conducted in some cities in Morocco. After gathering all the information, the data obtained were analyzed and summarized. The investigation has displayed emerging phycotherapy in Morocco. Consumers' knowledge about seaweeds is complex and various. Yet, most of them are convinced of their nutraceutical benefits for a healthy lifestyle. The healers strongly support the reliability of their recommendations in treating health problems according to what the literature shows. The present study has made a contribution in giving a clear picture of the status quo of dietary seaweeds therapies in Morocco, which is revealed as an emerging practice needed to renovate pharmacopeia. Therefore, it has allowed us to list some seaweeds that haven't been considered in any scientific investigation before, which will be subject afterward to pharmacological tests to prove the claimed uses.

Spirulina is a microalga used in traditional folk medicine in Morocco for the treatment of various health disorders. The wound healing activity of Moroccan Spirulina is unknown. In the current study, aqueous extracts ofSpirulina platensiswere investigated for acute toxicity and wound healing activity in Swiss Albino mice and White New Zealand rabbits, respectively. The LD50 (amount of substance required to kill 50% of the test population) of the microalga was greater than 5,000 mg/kg. Healing after application of the same amount of ointment on differently induced (mechanical, chemical, and thermal) wounds was about the same, over five weeks. Aqueous extract had remarkable healing activity on rabbits’ skin, possessing significantly greater healing effect for mechanical and chemical burns than controls. Moreover, the hair growing time was faster in treated groups; Spirulina-treated groups did not show any contamination with microbes compared to others. This study affirms thatSpirulina platensiscan be considered as a potential therapeutic agent for wound healing not only as a complementary medicine but also in conventional medicine.

Introduction: according to the World Health Organization (WHO), tuberculosis (TB) is a global emergency and a leading cause of death as a world bacterial disease. This dangerous disease affects poor and vulnerable populations, mainly seniors and children. This study aimed to describe the epidemiological profile of tuberculosis; based on clinical and evolutionary socio-demographic characteristics in the province of Sidi-Kacem. Methods: our study concerned the cases of tuberculosis diagnosed and treated in the center of tuberculosis and respiratory diseases of Sidi-Kacem during the years 2018 and 2019. The data were collected from the medical records of tuberculosis patients. Results: we recorded 1059 tuberculosis patients, representing an average rate of 100.77 new cases per 100000 inhabitants. Males represented 64.5% (n=683). The age average was 34.94 +/- 16.73 years. The majority of patients, 68.36% (n=724), are between 15 and 44 years old. Extrapulmonary TB represented 42.12% (n=623) compared to 58.88% (n=623) pulmonary TB, 78.30% (n=487) who had positive results for bacilloscopy. A lethality percentage of 1.7% (n=18) had observed. Conclusion: tuberculosis in the province of Sidi-Kacem is still claiming victims, and all sections of society exposing to this disease. Tuberculosis is more dangerous when it affects the lungs because this form is the one that contributes to infection and spread of the disease and causes more deaths. We hope that this research presented here will stimulate more strategies for adequate and specific case management of pulmonary tuberculosis and encourage treatment adherence.