Purpose: Parkinson’s Disease comes on top among neurodegenerative diseases affecting 10 million worldwide. To detect Parkinson’s Disease in a prior state, gait analysis is an effective choice. However, monitoring of Parkinson’s Disease using gait analysis is time consuming and exhaustive for patients and physicians. To assess severity of symptoms, a rating scale called Unified Parkinson's Disease Rating Scale is used. It determines mild and severe cases. Today, Parkinson’s Disease severity assessment is made in gait laboratories and by manual examination. These are time consuming and it is costly for health institutions to build and maintain laboratories. By using low-cost wearables and an effective model, aforementioned problems can be solved. Methods: We provide a computerized solution for quantifiable assessment of Parkinson’s Disease symptoms severity. By using wearable sensors, our framework can predict exact symptom values to assess Parkinson’s Disease severity. We propose a deep learning approach that utilizes Ground Reaction Force sensors. From sensor signals, features are extracted and fed to a hybrid deep learning model. This model is the combination of Convolutional Neural Networks and Locally Weighted Random Forest. Results: Proposed framework achieved 0.897, 3.009, 4.556 in terms of Correlation Coefficient, Mean Absolute Error and Root Mean Square Error, respectively. Proposed framework outperformed other machine and deep learning models. We also evaluated classification performance for disease detection. We outperformed most of the previous studies, achieving 99.5% accuracy, 98.7% sensitivity and 99.1% specificity. Conclusion: This is the first study to use a deep learning regression approach to predict exact symptom value of Parkinson’s Disease patients. Results show that this approach can be effectively employed as a disease severity assessment tool using wearable sensors.

Many individuals worldwide pass away as a result of inadequate procedures for prompt illness identification and subsequent treatment. A valuable life can be saved or at least extended with the early identification of serious illnesses, such as various cancers and other life-threatening conditions. The development of the Internet of Medical Things (IoMT) has made it possible for healthcare technology to offer the general public efficient medical services and make a significant contribution to patients’ recoveries. By using IoMT to diagnose and examine BreakHis v1 400× breast cancer histology (BCH) scans, disorders may be quickly identified and appropriate treatment can be given to a patient. Imaging equipment having the capability of auto-analyzing acquired pictures can be used to achieve this. However, the majority of deep learning (DL)-based image classification approaches are of a large number of parameters and unsuitable for application in IoMT-centered imaging sensors. The goal of this study is to create a lightweight deep transfer learning (DTL) model suited for BCH scan examination and has a good level of accuracy. In this study, a lightweight DTL-based model “MobileNet-SVM”, which is the hybridization of MobileNet and Support Vector Machine (SVM), for auto-classifying BreakHis v1 400× BCH images is presented. When tested against a real dataset of BreakHis v1 400× BCH images, the suggested technique achieved a training accuracy of 100% on the training dataset. It also obtained an accuracy of 91% and an F1-score of 91.35 on the test dataset. Considering how complicated BCH scans are, the findings are encouraging. The MobileNet-SVM model is ideal for IoMT imaging equipment in addition to having a high degree of precision. According to the simulation findings, the suggested model requires a small computation speed and time.

Infections encompass a set of medical conditions of very diverse kinds that can pose a significant risk to health, and even death. As with many other diseases, early diagnosis can help to provide patients with proper care to minimize the damage produced by the disease, or to isolate them to avoid the risk of spread. In this context, computational intelligence can be useful to predict the risk of infection in patients, raising early alarms that can aid medical teams to respond as quick as possible. In this paper, we survey the state of the art on infection prediction using computer science by means of a systematic literature review. The objective is to find papers where computational intelligence is used to predict infections in patients using physiological data as features. We have posed one major research question along with nine specific subquestions. The whole review process is thoroughly described, and eight databases are considered which index most of the literature published in different scholarly formats. A total of 101 relevant documents have been found in the period comprised between 2003 and 2019, and a detailed study of these documents is carried out to classify the works and answer the research questions posed, resulting to our best knowledge in the most comprehensive study of its kind. We conclude that the most widely addressed infection is by far sepsis, followed by Clostridium difficile infection and surgical site infections. Most works use machine learning techniques, from which logistic regression, support vector machines, random forest and naive Bayes are the most common. Some machine learning works provide some ideas on the problems of small data and class imbalance, which can be of interest. The current systematic literature review shows that automatic diagnosis of infectious diseases using computational intelligence is well documented in the medical literature.