Colostrum as a secretion of the mammary gland is produced and accumulated in the final stage of pregnancy and in the first days after calving. It is designed to provide the calf with the necessary nutrients and biologically active ingredients. One of the most difficult periods in the life of animals is their rearing, and the most sensitive are the first days after birth. This is the time when most falls occur, and they are caused by mortality and morbidity, even at the level of 30%. Such losses affect the performance and profitability of animal production (the percentage of animals intended for reproduction or fattening is reduced and the intensity of selection in the herd is also reduced). Both diseases and mortality are the cause of serious economic, production, and breeding losses, which are the result of weak immune mechanisms. The adaptability of calves to the environment is determined by their immune status. Colostrum has a regulating function and stimulates the young organism to grow, and it has properties that support the functioning of systems: Endocrine and immunological. For colostrum to fulfil its role, it must be administered immediately after birth, because the immunoglobulins it contains are absorbed during the first 16–27 h after the birth of the calf, preferably within 2–4 h of age. Blood from calves that have been properly calved should have an antibody concentration of 15g/L (24–48 h of age). Therefore, immunoglobulins are the most important factor affecting infectious immunity; an adequate concentration of immunoglobulins in calves’ blood is related to their survival and health. It is the intent of this review to synthesize and summarize the information currently available on colostrum, as well as to discuss the interpretation of the results.

Nowadays, mastitis is one of the biggest problems in breeding dairy cattle. Treatment of this disease with conventional antibiotics is ineffective because many pathogens are resistant. Researchers have therefore been forced to look for new solutions, and metal nanoparticles (NPs) have been found to be the most appropriate agents. This study uses commercially available silver (AgNPs) and copper (CuNPs) nanoparticles and synthetized silver–copper nanoparticles (AgCuNPs) to evaluate the effect of these NPs on human and bovine mammary cells. The effect of AgNPs, CuNPs, and AgCuNPs on pathogen species commonly involved in udder inflammation (e.g., Staphylococcus aureus and Escherichia coli) was also established. The results show that commercially available NPs were of good quality and did not have a toxic effect on mammary gland tissue. AgNPs, CuNPs, and AgCuNPs also influenced or decreased the viability of pathogens. Therefore, the presented data suggest that metal NPs could be used in mastitis prevention and treatment in the future. However, the presented preliminary results require further in vivo analysis.

Mastitis is one of the most common issues for milk producers around the world. Antibiotic therapy is often ineffective, and therefore, scientists must find a new solution. The aim of this paper is to estimate the influence of common and well-known cosmetic substrates and mixtures of nanoparticles (NPs) and cosmetic substrates on the viability of frequently occurring mastitis pathogens, Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The obtained results suggest that only collagen + elastin and glycerine influenced and increased bacteria viability. In case of the rest of the cosmetic substrates, the viability of E. coli and S. aureus was decreased, and the results were statistically significant (p ≤ 0.01). Prepared pre-dipping and dipping mixtures decrease (p ≤ 0.01) the viability of the mentioned pathogens. The obtained results of the in vitro analysis are very promising. In the next step, prepared mixtures should be tested in different herd conditions if they can be used in mastitis prevention or decrease the number of subclinical mastitis cases. Furthermore, these mixtures could become an interesting alternative for organic milk production where conventional preparations and antibiotics are forbidden. However, further analysis, especially on the influence of prepared mixtures on other bacteria species and, algae, fungi, are necessary.