Vladimir Dobričić

Dr. Vladimir Dobričić

Department of Pharmaceutical Chemistry, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia
orcid

Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 May 2020 in Drug Resistance Updates
Verified
Journal Article
Closed access
SDSabrina Dallavalle
Sabrina Dallavalle
Vladimir DobričićVladimir Dobričić
Vladimir Dobričić
LLLoretta Lazzarato
Loretta Lazzarato
EGElena Gazzano
Elena Gazzano
Miguel MachuqueiroMiguel Machuqueiro
Miguel Machuqueiro
Roberta FrutteroRoberta Fruttero
Roberta Fruttero

1 April 2020 in International Journal of Biological Macromolecules
Verified
Journal Article
Closed access
Ana R. ĆirićAna R. Ćirić
Ana R. Ćirić
ĐMĐorđe Medarević
Đorđe Medarević
BČBojan Čalija
Bojan Čalija
Vladimir DobričićVladimir Dobričić
Vladimir Dobričić
MMMiodrag Mitrić
Miodrag Mitrić
LĐLjiljana Đekić
Ljiljana Đekić

26 February 2018 in Journal of Medicinal Chemistry
Verified
Journal Article
Closed access
DKDaniel Knutson
Daniel Knutson
RKRevathi Kodali
Revathi Kodali
BDBranka Divović
Branka Divović
MTMarco Treven
Marco Treven
MSMichael Rajesh Stephen
Michael Rajesh Stephen
James CookJames Cook
James Cook

1 December 2015 in International Journal of Pharmaceutics
Verified
Journal Article
Closed access
JJJelena Janićijević
Jelena Janićijević
DKDanina Krajišnik
Danina Krajišnik
BČBojan Čalija
Bojan Čalija
BVBojana Nedić Vasiljević
Bojana Nedić Vasiljević
Vladimir DobričićVladimir Dobričić
Vladimir Dobričić
JMJela Milić
Jela Milić

13 August 2015 in Molecules
Verified
Journal Article
Open access
PDF file
MKMarko Z Krstić
Marko Z Krstić
MPMiljana Popović
Miljana Popović
Vladimir DobričićVladimir Dobričić
Vladimir Dobričić
Svetlana IbricSvetlana Ibric
Svetlana Ibric
The majority of drugs have a low dissolution rate, which is a limiting step for their absorption. In this manuscript, solid dispersions (SD), solid self-microemulsifying drug delivery systems (S-SMEDDS) and solid self-nanoemulsifying drug delivery systems (S-SNEDDS) were evaluated as potential formulation strategies to increase the dissolution rate of carbamazepine. Influence of increased dissolution rate on permeability of carbamazepine was evaluated using PAMPA test. In S-SMEDDS and S-SNEDDS formulations, the ratio of liquid SMEDDS/SNEDDS and solid carrier (Neusilin® UFL2) was varied, and carbamazepine content was constant. In SD formulations, the ratio of carbamazepine and Neusilin® UFL2, was varied. Formulations that showed the best dissolution rate of carbamazepine (SD_1:6, SMEDDS_1:1, SNEDDS_1:6) were mutually compared, characterization of these formulations was performed by DSC, PXRD and FT-IR analyses, and a PAMPA test was done. All formulations have shown a significant increase in dissolution rate compared to pure carbamazepine and immediate-release carbamazepine tablets. Formulation S-SMEDDS_1:1 showed the fastest release rate and permeability of carbamazepine. DSC, PXRD and FT-IR analyses confirmed that in S-SMEDDS and S-SNEDDS carbamazepine remained in polymorph form III, and that it was converted to an amorphous state in SD formulations. All formulations showed increased permeability of carbamazepine, compared to pure carbamazepine.

1 January 2021 in International Journal of Biological Macromolecules
Verified
Journal Article
Closed access
Ana R. ĆirićAna R. Ćirić
Ana R. Ćirić
ĐMĐorđe Medarević
Đorđe Medarević
BČBojan Čalija
Bojan Čalija
Vladimir DobričićVladimir Dobričić
Vladimir Dobričić
MRMilena Rmandic
Milena Rmandic
LĐLjiljana Đekić
Ljiljana Đekić