A novel promising electrochemical nicotine (NIC) sensor was prepared by electrodeposition of Ce-nanoparticles on a carbon paste electrode (CPE). Electrochemical techniques including cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscope (SEM) and Energy Dispersive X-ray Analysis (EDX) techniques, in both aqueous and micellar media were used. NIC measurements were investigated in Britton–Robinson (B–R) buffer solutions with a pH range (2.0–8.0) containing (1.0 mM) sodium dodecyl sulfate (SDS). The linear response range of the sensor was between 4 × 10⁻⁶ M and 5 × 10⁻⁴ M with a detection limit of 9.43 × 10⁻⁸ M. Good results were achieved for the detection of NIC in real samples and with different brands of commercial cigarettes.

A novel nano-composite film coat of organic/inorganic composition including chitosan (CS), TiO ₂ nanoparticles (TO) and hydroxyapatite (HA) nanoparticles, was synthesized on a Ti–6Al–4V alloy surface.