Katia Mangano

Prof. Katia Mangano

orcid

Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 February 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
GLGian Marco Leone
Gian Marco Leone
KMKatia Mangano
Katia Mangano
MPMaria Cristina Petralia
Maria Cristina Petralia
Ferdinando NicolettiFerdinando Nicoletti
Ferdinando Nicoletti
Paolo FagonePaolo Fagone
Paolo Fagone
Due to the key role of tumor necrosis factor-alpha (TNF-α) in the pathogenesis of immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and used in the clinical treatment of autoimmune disorders. Currently, five anti-TNF-α drugs have been approved: infliximab, adalimumab, golimumab, certolizumab pegol and etanercept. Anti-TNF-α biosimilars are also available for clinical use. Here, we will review the historical development as well as the present and potential future applications of anti-TNF-α therapies, which have led to major improvements for patients with several autoimmune diseases, such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), Crohn’s disease (CD), ulcerative colitis (UC), psoriasis (PS) and chronic endogenous uveitis. Other therapeutic areas are under evaluation, including viral infections, e.g., COVID-19, as well as chronic neuropsychiatric disorders and certain forms of cancer. The search for biomarkers able to predict responsiveness to anti-TNF-α drugs is also discussed.

3 January 2018 in Oncotarget
Verified
Journal Article
Open access
PDF file
SMSanta Mammana
Santa Mammana
PBPlacido Bramanti
Placido Bramanti
EMEmanuela Mazzon
Emanuela Mazzon
ECEugenio Cavalli
Eugenio Cavalli
MBMaria Sofia Basile
Maria Sofia Basile
KMKatia Mangano
Katia Mangano
Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis

24 July 2001 in Neurology
Verified
Journal Article
Closed access
PDF file
Ferdinando NicolettiFerdinando Nicoletti
Ferdinando Nicoletti
Roberto (Maria Antonio) Di MarcoRoberto (Maria Antonio) Di Marco
Roberto (Maria Antonio) Di Marco
KMKatia Mangano
Katia Mangano
FPF. Patti
F. Patti
ERE. Reggio
E. Reggio
ARA. Reggio
A. Reggio
Serum but not CSF concentrations of the interferon-γ-inducing cytokine interleukin (IL)-18 were significantly augmented in patients with MS as compared to both healthy controls and patients with other neurologic diseases. Patients with MS with secondary chronic progressive disease had significantly higher serum levels than those with relapsing remitting MS. In the latter group, IL-18 levels were higher in patients with acute exacerbation as compared to those with stable disease.

2 February 2014 in Diabetologia
Verified
Journal Article
Closed access
PDF file
INIvana Nikolic
Ivana Nikolic
TSTamara Saksida
Tamara Saksida
KMKatia Mangano
Katia Mangano
MVMilica Vujicic
Milica Vujicic
ISIvana Stojanović
Ivana Stojanović
SSStanislava Stosic-Grujicic
Stanislava Stosic-Grujicic

1 February 2009 in Journal of Neuroimmunology
Verified
Journal Article
Closed access
IDIrena Dujmovic
Irena Dujmovic
KMKatia Mangano
Katia Mangano
TPTatjana Pekmezovic
Tatjana Pekmezovic
CQCinzia Quattrocchi
Cinzia Quattrocchi
SMSarlota Mesaros
Sarlota Mesaros
JDJelena Drulovic
Jelena Drulovic

3 April 2018 in Oncotarget
Verified
Journal Article
Open access
PDF file
KMKatia Mangano
Katia Mangano
EMEmanuela Mazzon
Emanuela Mazzon
MBMaria Sofia Basile
Maria Sofia Basile
Roberto (Maria Antonio) Di MarcoRoberto (Maria Antonio) Di Marco
Roberto (Maria Antonio) Di Marco
PBPlacido Bramanti
Placido Bramanti
Ferdinando NicolettiFerdinando Nicoletti
Ferdinando Nicoletti
Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach