This article presents an evaluation of the influence on the natural carbonation process of the use of granite cutting residue as a replacement for fine aggregate in mortars. The methodology adopted consisted of replacing the fine aggregate with granite cutting residue, analysing the carbonation depth with the aid of an experimental planning matrix of 2³ + 3 repetitions at the central point. The influence of the exposure time, the percentage of residue in the mixture, and the particle size of the residue used were evaluated. The exposure time variable was found to have the greatest influence on the carbonation process. Under the conditions analysed, granite residue was found to be beneficial, reducing the carbonation depth.