An approximate comparison of neodymium sorption at pH=1.5, between the well studied Saccharomyces cerevisiae and three other related microorganisms ( Kluyveromyces marxianus , Candida colliculosa and Debaromyces hansenii ) was made. Although big differences were not observed, a slightly higher neodymium uptake was attained by the latter three kinds of yeasts. Their adsorption isotherms, varying the initial metal concentration from 10 to 200 mg/L, at constant ionic strength ( I =0.1 mol/L), could be fitted equally well, either to Langmuir or Freundlich adsorption model. Their estimated values of q max and K f , which are related to adsorption capacity, ranged from 10−12 mg/g and 0.90–1.2 respectively. The corresponding Scatchard plots suggest two types of bonding sites for all yeast studied and common receptor sites between C. colliculosa and D. hansenii . It is also discussed, the feasibility of using all these microorganisms, as potential detoxification tools, wherever contamination of foodstuffs by radionuclides, seems to be probable.