The early detection of melanoma is the most efficient way to reduce its mortality rate. Dermatologists achieve this task with the help of dermoscopy, a non-invasive tool allowing the visualization of patterns of skin lesions. Computer-aided diagnosis (CAD) systems developed on dermoscopic images are needed to assist dermatologists. These systems rely mainly on multiclass classification approaches. However, the multiclass classification of skin lesions by an automated system remains a challenging task. Decomposing a multiclass problem into a binary problem can reduce the complexity of the initial problem and increase the overall performance. This paper proposes a CAD system to classify dermoscopic images into three diagnosis classes: melanoma, nevi, and seborrheic keratosis. We introduce a novel ensemble scheme of convolutional neural networks (CNNs), inspired by decomposition and ensemble methods, to improve the performance of the CAD system. Unlike conventional ensemble methods, we use a directed acyclic graph to aggregate binary CNNs for the melanoma detection task. On the ISIC 2018 public dataset, our method achieves the best balanced accuracy (76.6%) among multiclass CNNs, an ensemble of multiclass CNNs with classical aggregation methods, and other related works. Our results reveal that the directed acyclic graph is a meaningful approach to develop a reliable and robust automated diagnosis system for the multiclass classification of dermoscopic images.
Early detection of melanoma remains a daily challenge due to the increasing number of cases and the lack of dermatologists. Thus, AI-assisted diagnosis is considered as a possible solution for this issue. Despite the great advances brought by deep learning and especially convolutional neural networks (CNNs), computer-aided diagnosis (CAD) systems are still not used in clinical practice. This may be explained by the dermatologist’s fear of being misled by a false negative and the assimilation of CNNs to a “black box”, making their decision process difficult to understand by a non-expert. Decision theory, especially game theory, is a potential solution as it focuses on identifying the best decision option that maximizes the decision-maker’s expected utility. This study presents a new framework for automated melanoma diagnosis. Pursuing the goal of improving the performance of existing systems, our approach also attempts to bring more transparency in the decision process. The proposed framework includes a multi-class CNN and six binary CNNs assimilated to players. The players’ strategies is to first cluster the pigmented lesions (melanoma, nevus, and benign keratosis), using the introduced method of evaluating the confidence of the predictions, into confidence level (confident, medium, uncertain). Then, a subset of players has the strategy to refine the diagnosis for difficult lesions with medium and uncertain prediction. We used EfficientNetB5 as the backbone of our networks and evaluated our approach on the public ISIC dataset consisting of 8917 lesions: melanoma (1113), nevi (6705) and benign keratosis (1099). The proposed framework achieved an area under the receiver operating curve (AUROC) of 0.93 for melanoma, 0.96 for nevus and 0.97 for benign keratosis. Furthermore, our approach outperformed existing methods in this task, improving the balanced accuracy (BACC) of the best compared method from 77% to 86%. These results suggest that our framework provides an effective and explainable decision-making strategy. This approach could help dermatologists in their clinical practice for patients with atypical and difficult-to-diagnose pigmented lesions. We also believe that our system could serve as a didactic tool for less experienced dermatologists.
29 January 2024 in Journal of Investigative Dermatology
Melanoma is still a major health problem worldwide. The early diagnosis is the first step toward reducing its mortality, but it remains a challenge even for experienced dermatologists. While computer-aided systems have been developed to help the diagnosis, the lack of insight of their predictions is still a significant limitation towards acceptance by the medical community. To tackle this issue, we designed handcrafted expert features representing color asymmetry within the lesions, which are parts of the approach used by dermatologists in their daily practice. These features are given to an artificial neural network (ANN) classifying between nevi and melanoma. We compare our results with an ensemble of seven state-of-the-art CNNs and merge the two approaches by computing the average prediction. Our experiments are done on a subset of the International Skin Imaging Collaboration (ISIC) 2019 dataset (6296 nevi, 1361 melanomas). The ANN based on asymmetry achieved an AUC of 0.873, Sensitivity 90%, Specificity 67%, the CNN approach achieved an AUC of 0.938, Sensitivity 91%, Specificity 82%, and the fusion of both approaches was 0.942, Sensitivity 92%, Specificity 82%. Merging the knowledge of dermatologists with CNNs showed high performances for melanoma detection, encouraging collaboration between computer science and medical fields.
Due to its increasing incidence, skin cancer, and especially melanoma, is considered a major public health issue. Manually detecting skin lesions (SL) from dermoscopy images is a difficult and time-consuming process. Thus, researchers designed computer-aided diagnosis (CAD) systems to assist dermatologists in the early detection of skin cancer. Moreover, SL detection naturally exhibits a long-tailed distribution due to the complex patient-level conditions and the existence of rare diseases. Very limited research for handling this issue exists on SL detection. In this paper, we propose an end-to-end decoupled training for the long-tailed skin lesion classification task. Specifically, we initialized the training of a network with a novel loss function able to guide the model to a better representation of the features. Then, we fine-tuned the pretrained networks with a weighted variant of helping to improve the robustness of the network to class imbalance. We evaluated our model on the ISIC 2018 public dataset against existing methods for handling class imbalance and existing approaches for SL detection. The results demonstrated the superiority of our framework, outperforming all compared methods by a minimum margin of 2% with a single model.
This study provides an in-depth analysis of GAF-Net, a novel model for video-based person re-identification (Re-ID) that matches individuals across different video sequences. GAF-Net combines appearance-based features with gait-based features derived from skeletal data, offering a new approach that diverges from traditional silhouette-based methods. We thoroughly examine each module of GAF-Net and explore various fusion methods at the both score and feature levels, extending beyond initial simple concatenation. Comprehensive evaluations on the iLIDS-VID and MARS datasets demonstrate GAF-Net’s effectiveness across scenarios. GAF-Net achieves state-of-the-art rank-1 accuracy on iLIDS-VID’s long sequences, while MARS results ( mAP, rank-1) reveal challenges with shorter, variable sequences in complex real-world settings. We demonstrate that integrating skeleton-based gait features consistently improves Re-ID performance, particularly with long, more informative sequences. This research provides crucial insights into multi-modal feature integration in Re-ID tasks, laying a foundation for the advancement of multi-modal biometric systems for diverse computer vision applications.