In order to guarantee the service performance of recycling asphalt mixture with reclaimed asphalt pavement (RAP), asphalt rejuvenator shall be added. In the last five years, vegetable oil-based rejuvenators have received more and more attention due to their green and regenerative advantages. The object of this paper is to investigate the feasibility of rejuvenating aged asphalt by a kind of waste vegetable oil (W-oil). The effect of W-oil on the performance of aged asphalt is characterized by a safety property test, aging property test, and pavement performance tests; the pavement performance tests included traditional tests and a rheological test. The results show that both the safety property and aging property of rejuvenated asphalt with W-oil meet the specification requirements. According to the results of traditional performance indexes (i.e., penetration, soften point, and ductility), the pavement performance of rejuvenated asphalt can be recovered to the level of virgin asphalt. According to the results of performance indices obtained from the rheological test, the optimum dosage of W-oil is determined to be 13.4 wt %. Compared with virgin asphalt, the rutting property of rejuvenated asphalt is equivalent to that of virgin asphalt, and the workability is slightly poorer; however, the fatigue property and low temperature property have been significantly enhanced. W-oil cannot only improve the pavement performance of aged asphalt, it can also guarantee good safety property and aging property. Therefore, W-oil is of great potential to serve as an asphalt rejuvenator for rejuvenating aged asphalt.

Pavement skid resistance is an important guarantee for driving safety. However, it is very difficult to determine the exact friction in a field environment. In order to overcome the limitations of traditional evaluation methods, the effect mechanism of surface 3D (three-dimensional) texture on skid resistance was firstly analyzed. Then the surface 3D texture of pavement was acquired through an improved binocular reconstruction method. Additionally, the relationship between friction coefficient and 3D texture was also analyzed. Subsequently, under the concept of IFI (international friction index) used to harmonize different detection methods of skid resistance, the evaluation model of skid resistance based 3D texture was further established. The results showed that the multiple quadratic multinomial regression model can well describe the relationship between skid resistance and texture indicators. The establishment of an improved evaluation model is simple to operate and implement. It can directly evaluate the skid resistance on pavement surface once the aggregates’ type and 3D texture are known. This evaluation model not only overcomes the challenges of friction coefficient with a strong conditional restriction, but also provides a harmonious approach for different detection methods in the evaluation of pavement skid resistance.

To study dynamic changes in pavement skid resistance, this paper presents a new decay model. The new decay model is a grey model established based on three-dimensional (3D) texture using quadratic fitting, which just requires one small sample of data. The prediction accuracy of the proposed model is examined. Additionally, the model’s prediction effect and the influence of different factors on decay characteristics are further analysed. Results indicate that the new decay model can well describe the decay characteristics of the pavement skid resistance. In terms of macrotexture, the decay rate and the terminal value both change in a favorable direction as the abrasion resistance of aggregates increases. During the decay process, stone mastic asphalt (SMA) has a minimum decay rate and a relatively large terminal value. In terms of microtexture indicators, the decay characteristics are more complex. The reason may be that the microtexture is continuously regenerated under the abrasion action during the decay process. The decay rate of asphalt concrete (AC) is low, and the terminal values of the SMA and open-graded friction course (OGFC) are relatively high. The results of this study are helpful to deeply understand the decay characteristics of pavement skid resistance, which have a guiding significance for the establishment of a decay model of skid resistance using small samples.

DXM is widely used as an antifibrotic agent due to its protection of the lungs against fibrosis by inhibiting the production of inflammatory mediators. Many studies clearly indicated that the time point at which DXM treatment started, the dose and the duration of intervention are critical for exerting its antifibrotic effect. Exploring the role of DXM in the occurrence and development of PF at different stages is the fundamental purpose of this article. Lung fibrosis was persuaded in Sprague-Dawley rats by a single intratracheal BLM (5 mg/kg) injection. This experiment was divided into two animal experiments and treated with DXM following or after bleomycin administration respectively. The biochemical, histopathological and molecular alterations were studied in the lung tissues. A long course of low-dose DXM had the ability to ameliorate PF induced by BLM via decreasing inflammation and improving oxidative stress through modulation of TGF-β/Smad, PI3K/Akt/mTOR and NF-κB signaling pathway. Long course of low-dose DXM intake following or after bleomycin administration both had therapeutic effects on pulmonary fibrosis.

For such a specific object as asphalt pavement with inconspicuous feature points, the traditional image vision algorithm has limited effect on its texture measurement. In order to realize the high-resolution, high-precision, and convenient detection of three-dimensional (3D) pavement texture while better serving traffic safety, the traditional binocular reconstruction technology was improved in this study threefold. First, the improved binocular reconstruction test system and the measurement accuracy evaluation device were manufactured to realize the reconstruction of the 3D texture and the true point-to-point evaluation of measurement accuracy. Second, the global scanning constraint posed by a moving laser line was introduced to shoot video images, which formed numerous mandatory constraints and improved the matching accuracy. Last, the centroid enhanced subregion segmentation algorithm was proposed to complete stereo matching under global scanning constraint. Results show that the binocular reconstruction algorithm improved by moving a laser line constraint under a centroid enhanced subregion segmentation matching mode can significantly improve the accuracy in the measurement of asphalt pavement 3D texture. Ultimately, the test results can meet the precision requirement of micro-texture.