Birgit Lange

Dr. Birgit Lange


Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 September 2015 in Lasers in Surgery and Medicine
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BLBirgit Lange
Birgit Lange
JCJens Cordes
Jens Cordes
RBRalf Brinkmann
Ralf Brinkmann

12 November 2016 in Lasers in Surgery and Medicine
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Journal Article
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BLBirgit Lange
Birgit Lange
DJDieter Jocham
Dieter Jocham
RBRalf Brinkmann
Ralf Brinkmann
JCJens Cordes
Jens Cordes

30 October 2013 in Advances in Urology
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Journal Article
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JCJens Cordes
Jens Cordes
FNFelix Nguyen
Felix Nguyen
BLBirgit Lange
Birgit Lange
RBRalf Brinkmann
Ralf Brinkmann
DJDieter Jocham
Dieter Jocham
Background. In some cases, the ureteral stone is simultaneously stabilized by a stone basket when endourologic lithotripsy is performed. This stabilization can be either on purpose or by accident. By accident means that an impaction in the ureter occurs by an extraction of a stone with a basket. A stabilization on purpose means to avoid a retropulsion of the stone into the kidney during lithotripsy. At this part of the operation, stone baskets have been frequently damaged. This severing of wires can lead to ureteral trauma because of hook formation.Material and Methods. In a laboratory setting, the time and the pulse numbers were measured until breaking the wires from four different nitinol stone baskets by using five different lithotripsy devices. The endpoint was gross visibledamage to the wire and loss of electric conduction.Results. The Ho:YAG laser and the ultrasonic device were able to destroy almost all the wires. The ballistic devices and the electrohydraulic device were able to destroy thin wires.Conclusion. The operating surgeon should know the risk of damagefor every lithotripter. The Ho:YAG-laser and the ultrasonic device should be classified as dangerous for the basket wire with all adverse effects to the patient.

11 September 2019 in Lasers in Surgery and Medicine
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BLBirgit Lange
Birgit Lange
JCJens Cordes
Jens Cordes
RBRalf Brinkmann
Ralf Brinkmann

18 May 2023 in Journal of Biophotonics
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BLBirgit Lange
Birgit Lange
TOT. Ozimek
T. Ozimek
JWJ. R. Wießmeyer
J. R. Wießmeyer
MKM. W. Kramer
M. W. Kramer
AMA. S. Merseburger
A. S. Merseburger
RBR. Brinkmann
R. Brinkmann
In clinically approved laser lithotripsy systems, there is no automatic monitoring of fiber position to date. We investigated whether detecting stone autofluorescence, excited by a green aiming beam, is possible via the fiber during fragmentation by continuously recording the fluorescence signal in 12 ureterosopic lithotripsy procedures. We estimated which threshold the fluorescence signal's amplitude exceeds before laser pulses with visible stone removal by retrospective inspection of the endoscope's video data. For all procedures, blocking the laser when the fluorescence amplitude is below a threshold corresponding to the signal's baseline plus its range (maximum–minimum value) would have been appropriate to suppress ineffective pulses—the energy input could have been reduced by a mean of 14% (1%–29%) without changing the operation time. Ablation of the PTFE coating of the guidewire could have been prevented three times and cutting of a wire of the retrieval basket two times.

26 March 2024 in Sensors
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ABAndrey Boyko
Andrey Boyko
BLBirgit Lange
Birgit Lange
SESebastian Eckert
Sebastian Eckert
FMFedor Mayorov
Fedor Mayorov
RBRalf Brinkmann
Ralf Brinkmann
Differential photoacoustic spectroscopy (DPAS) cells are usually excited on the first longitudinal ring mode, with a microphone situated in the middle of each of the two resonator tubes. However, it is known from other photoacoustic spectroscopy cell designs that connecting the microphones via a capillary can lead to signal enhancement. By means of finite element method (FEM) simulations, we compared such a photoacoustic spectroscopy (PAS) cell with a capillary to a DPAS cell with a capillary attached to each of the two resonators and showed that the behavior of both systems is qualitatively the same: In both the PAS and the DPAS cell, in-phase and anti-phase oscillations of the coupled system (resonator–capillary) can be excited. In the DPAS cell, capillaries of suitable length also increase the pressure signal at the microphones according to the FEM simulations. For different capillary diameters (1.2 mm/1.7 mm/2.2 mm), the respective optimal capillary length (36–37.5 mm) and signal amplification was determined (94%, 70%, 53%). According to the results of these FEM simulations, a significant increase in sensitivity can, therefore, also be achieved in DPAS cells by expanding them with thin tubes leading to the microphones.