BOŻENA KICZOROWSKA

Prof. BOŻENA KICZOROWSKA

orcid

Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 January 2016 in Postępy Higieny I Medycyny Doświadczalnej
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Journal Article
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AAAli Ridha Mustafa Al-Yasiry
Ali Ridha Mustafa Al-Yasiry
BKBOŻENA KICZOROWSKA
BOŻENA KICZOROWSKA
Recently, increasing interest in natural dietary and therapeutic preparations used as dietary supplements has been observed. One of them is frankincense. This traditional medicine of the East is believed to have anti-inflammatory, expectorant, antiseptic, and even anxiolytic and anti-neurotic effects. The present study aims to verify the reported therapeutic properties of Boswellia resin and describe its chemical composition based on available scientific studies. The main component of frankincense is oil (60%). It contains mono- (13%) and diterpenes (40%) as well as ethyl acetate (21.4%), octyl acetate (13.4%) and methylanisole (7.6%). The highest biological activity among terpenes is characteristic of 11-keto-ß-acetyl-beta-boswellic acid, acetyl-11-keto-ß-boswellic acid and acetyl-α-boswellic acid. Contemporary studies have shown that resin indeed has an analgesic, tranquilising and anti-bacterial effects. From the point of view of therapeutic properties, extracts from Boswellia serrata and Boswellia carterii are reported to be particularly useful. They reduce inflammatory conditions in the course of rheumatism by inhibiting leukocyte elastase and degrading glycosaminoglycans. Boswellia preparations inhibit 5-lipoxygenase and prevent the release of leukotrienes, thus having an anti-inflammatory effect in ulcerative colitis, irritable bowel syndrome, bronchitis and sinusitis. Inhalation and consumption of Boswellia olibanum reduces the risk of asthma. In addition, boswellic acids have an antiproliferative effect on tumours. They inhibit proliferation of tumour cells of the leukaemia and glioblastoma subset. They have an anti-tumour effect since they inhibit topoisomerase I and II-alpha and stimulate programmed cell death (apoptosis).

1 March 2017 in European Food Research and Technology
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Journal Article
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EGEugeniusz Grela
Eugeniusz Grela
BKBOŻENA KICZOROWSKA
BOŻENA KICZOROWSKA
WSWioletta Samolińska
Wioletta Samolińska
JMJan Matras
Jan Matras
PKPiotr Kiczorowski
Piotr Kiczorowski
EHEwa Hanczakowska
Ewa Hanczakowska
The aim of the study was to determine and analyse the content of essential nutrients, the amino acid profile, phytochemical compounds, and antioxidant activity in the seeds of selected species and varieties of Fabaceae plants. The highest total protein content was detected in the seeds of the yellow and Andean lupines. The lupine seeds were characterised by a high (P < 0.05) level of crude fibre, NDF, and CEL. The highest proportion of EAAI (77%) was noted in the protein of chickpea, broad bean, grasspea, and pea. Among the Fabaceae plants analysed, chickpea seeds exhibited the highest (P < 0.05) levels of total phenols and polyphenols. The greatest (P < 0.05) antioxidant activity (DPPH) was noted for the lentil and yellow lupine seeds. Compared to the other legume representatives, the importance of lupine is increasing, as the chemical composition of its seeds makes the plant an important nutraceutical component.

26 July 2017 in Annals of Animal Science
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BKBOŻENA KICZOROWSKA
BOŻENA KICZOROWSKA
WSWioletta Samolińska
Wioletta Samolińska
AAAli Ridha Mustafa Al-Yasiry
Ali Ridha Mustafa Al-Yasiry
PKPiotr Kiczorowski
Piotr Kiczorowski
AWAnna Winiarska-Mieczan
Anna Winiarska-Mieczan
Probiotics, prebiotics, and phytobiotics could be a possible solution as immunostimulants in monogastric animal nutrition. Beneficial effects of application thereof in animals are determined by many factors, e.g. the type of the probiotic strain, probiotic compounds, or plant species used as a supplement. A significant role is also played by the animal species, dosage, and the time and method of administration. The activity of these compounds is primarily focused on prevention of pathogen infections and, consequently, improvement of animal welfare. Probiotics compete with pathogenic bacteria by covering the intestinal epithelium mucosa, thereby interrupting pathogen colonization in the gastrointestinal tract. Supplementation with probiotics, prebiotics, and phytobiotics can also induce positive changes in the intestinal morphology, e.g. elongation of villi or deepening of intestinal crypts. In a majority of cases, they also modulate the immune response of the host. They mobilise the cellular components of the innate immune system (macrophages and heterophils), which defend the animal organism against gastrointestinal infection. Another possibility is the synthesis and release of pro-inflammatory cytokines that modulate adaptive immunity or stabilization of the intestinal microbiome. The main target of immunomodulatory feed additives is reduction of local inflammation, enhancement of the function of the immune system, a substantial impact on the health status of livestock animals, and improvement of their health status and production performance.

4 August 2022 in Scientific Reports
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PKPiotr Kiczorowski
Piotr Kiczorowski
BKBOŻENA KICZOROWSKA
BOŻENA KICZOROWSKA
WSWioletta Samolińska
Wioletta Samolińska
MSMarek Szmigielski
Marek Szmigielski
AWAnna Winiarska-Mieczan
Anna Winiarska-Mieczan
In the present study, the dry matter, crude ash, crude protein, ether extract, and energy, macro- (Na, K, Ca, Mg, P), micro- (Zn, Cu, Fe) minerals, heavy metals (Pb, Cd), vitamin C, A, carotene, and phenolic content were determined in chosen raw and fermented vegetables. The dietary intake of several macro- and microconstituents per one serving (100 g or humans and animals: ducks and pigs) was calculated. The fermentation process was found to reduce water and increase fat content in the vegetables. Lower levels of vitamin C and phenols were also found in the fermented vegetables. The vitamin A and carotene content in the fermented carrots and peppers were increased in comparison with the raw vegetables. The fermentation process decreased the concentration of some basic nutrients, mineral content, vitamins C and A, and phenols. Broccoli, peppers, and red beet had the highest levels of the analyzed nutrients and bioconstituents. The fermentation process is regarded by nutritionists as beneficial to human health. The addition of fermented plants is recommended in animal nutrition as well. This process modifies the chemical composition of preserved vegetables, e.g. it reduces the concentration of dietary fiber, and brings favorable effects in poultry and pig nutrition.

29 March 2017 in Biological Trace Element Research
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EGEugeniusz Grela
Eugeniusz Grela
WSWioletta Samolińska
Wioletta Samolińska
BKBOŻENA KICZOROWSKA
BOŻENA KICZOROWSKA
RKRenata Klebaniuk
Renata Klebaniuk
PKPiotr Kiczorowski
Piotr Kiczorowski
The aim of the study was to determine the mineral composition and fatty acid profile in the seeds of selected Fabaceae species and cultivars and to assess their correlations with phytochemicals and antioxidant activity. The Andean lupine was characterised by a particularly high level of Mg and K as well as Cu, Zn, and Fe (P < 0.05). There were various correlations (P < 0.05) between the total phenols and tannins and these elements. The highest contribution of α-linolenic acid (ALA, 18:3, n-3) in total fatty acids was noted in the lentil (13.8 in 100 g−1 fat), common bean (11.9 in 100 g−1 fat), and pea seeds (10.4 in 100 g−1 fat) (P = 0.028). In turn, the white lupine contained the highest content of ALA—0.67 g 100 g−1 seeds; its lowest level was determined in the broad bean—0.03 g 100 g−1 seeds. The seeds exhibited a high proportion of hypocholesterolemic fatty acids (on average 86%). The 2,2-diphenyl-1-picrylhydrazyl antiradical activity was positively correlated with UFA and PUFA (P < 0.05). This indicates great protective potential of legume seeds for prevention and treatment of diet-dependent diseases.

8 February 2020 in Nutrients
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AWAnna Winiarska
Anna Winiarska
EBEwa Baranowska-Wójcik
Ewa Baranowska-Wójcik
MKMałgorzata Kwiecień
Małgorzata Kwiecień
EGEugeniusz Grela
Eugeniusz Grela
Dominik SzwajgierDominik Szwajgier
Dominik Szwajgier
BKBOŻENA KICZOROWSKA
BOŻENA KICZOROWSKA
Neurodegenerative diseases are progressive diseases of the nervous system that lead to neuron loss or functional disorders. Neurodegenerative diseases require long-term, sometimes life-long pharmacological treatment, which increases the risk of adverse effects and a negative impact of pharmaceuticals on the patients’ general condition. One of the main problems related to the treatment of this type of condition is the limited ability to deliver drugs to the brain due to their poor solubility, low bioavailability, and the effects of the blood-brain barrier. Given the above, one of the main objectives of contemporary scientific research focuses on the prevention of neurodegenerative diseases. As disorders related to the competence of the antioxidative system are a marker in all diseases of this type, the primary prophylactics should entail the use of exogenous antioxidants, particularly ones that can be used over extended periods, regardless of the patient’s age, and that are easily available, e.g., as part of a diet or as diet supplements. The paper analyzes the significance of the oxidoreductive balance in the pathogenesis of neurodegenerative diseases. Based on information published globally in the last 10 years, an analysis is also provided with regard to the impact of exogenous antioxidants on brain functions with respect to the prevention of this type of diseases.