Electroencephalogram signals are used to assess neurodegenerative diseases and develop sophisticated brain machine interfaces for rehabilitation and gaming. Most of the applications use only motor imagery or evoked potentials. Here, a deep learning network based on a sensory motor paradigm (auditory, olfactory, movement, and motor-imagery) that employs a subject-agnostic Bidirectional Long Short-Term Memory (BLSTM) Network is developed to assess cognitive functions and identify its relationship with brain signal features, which is hypothesized to consistently indicate cognitive decline. Testing occurred with healthy subjects of age 20–40, 40–60, and >60, and mildly cognitive impaired subjects. Auditory and olfactory stimuli were presented to the subjects and the subjects imagined and conducted movement of each arm during which Electroencephalogram (EEG)/Electromyogram (EMG) signals were recorded. A deep BLSTM Neural Network is trained with Principal Component features from evoked signals and assesses their corresponding pathways. Wavelet analysis is used to decompose evoked signals and calculate the band power of component frequency bands. This deep learning system performs better than conventional deep neural networks in detecting MCI. Most features studied peaked at the age range 40–60 and were lower for the MCI group than for any other group tested. Detection accuracy of left-hand motor imagery signals best indicated cognitive aging (p = 0.0012); here, the mean classification accuracy per age group declined from 91.93% to 81.64%, and is 69.53% for MCI subjects. Motor-imagery-evoked band power, particularly in gamma bands, best indicated (p = 0.007) cognitive aging. Although the classification accuracy of the potentials effectively distinguished cognitive aging from MCI (p < 0.05), followed by gamma-band power.

Hyperspectral remote sensing has tremendous potential for monitoring land cover and water bodies from the rich spatial and spectral information contained in the images. It is a time and resource consuming task to obtain groundtruth data for these images by field sampling. A semi-supervised method for labeling and classification of hyperspectral images is presented. The unsupervised stage consists of image enhancement by feature extraction, followed by clustering for labeling and generating the groundtruth image. The supervised stage for classification consists of a preprocessing stage involving normalization, computation of principal components, and feature extraction. An ensemble of machine learning models takes the extracted features and groundtruth data from the unsupervised stage as input and a decision block then combines the output of the machines to label the image based on majority voting. The ensemble of machine learning methods includes support vector machines, gradient boosting, Gaussian classifier, and linear perceptron. Overall, the gradient boosting method gives the best performance for supervised classification of hyperspectral images. The presented ensemble method is useful for generating labeled data for hyperspectral images that do not have groundtruth information. It gives an overall accuracy of 93.74% for the Jasper hyperspectral image, 100% accuracy for the HSI2 Lake Erie images, and 99.92% for the classification of cyanobacteria or harmful algal blooms and surface scum. The method distinguishes well between blue green algae and surface scum. The full pipeline ensemble method for classifying Lake Erie images in a cloud server runs 24 times faster than a workstation.

Photovoltaic (PV) power generation forecasting is an important research topic, aiming to mitigate variability caused by weather conditions and improve power generation planning. Climate factors, including solar irradiance, temperature, and cloud cover, influence the energy conversion achieved by PV systems. Long-term weather forecasting improves PV power generation planning, while short-term forecasting enhances control methods, such as managing ramp rates. The stochastic nature of weather variables poses a challenge for linear regression methods. Consequently, advanced, state-of-the-art machine learning (ML) approaches capable of handling non-linear data, such as long short-term memory (LSTM), have emerged. This paper introduces the implementation of a multivariate machine learning model to forecast PV power generation, considering multiple weather variables. A deep learning solution was implemented to analyze weather variables in a short time horizon. Utilizing a hidden Markov model for data preprocessing, an LSTM model was trained using the Alice Spring dataset provided by DKA Solar Center. The proposed workflow demonstrated superior performance compared to the results obtained by state-of-the-art methods, including support vector machine, radiation classification coordinate with LSTM (RCC-LSTM), and ESNCNN specifically concerning the proposed multi-input single-output LSTM model. This improvement is attributed to incorporating input features such as active power, temperature, humidity, horizontal and diffuse irradiance, and wind direction, with active power serving as the output variable. The proposed workflow achieved a mean square error (MSE) of 2.17×10-7, a root mean square error (RMSE) of 4.65×10-4, and a mean absolute error (MAE) of 4.04×10-4.

A framework combining two powerful tools of hyperspectral imaging and deep learning for the processing and classification of hyperspectral images (HSI) of rice seeds is presented. A seed-based approach that trains a three-dimensional convolutional neural network (3D-CNN) using the full seed spectral hypercube for classifying the seed images from high day and high night temperatures, both including a control group, is developed. A pixel-based seed classification approach is implemented using a deep neural network (DNN). The seed and pixel-based deep learning architectures are validated and tested using hyperspectral images from five different rice seed treatments with six different high temperature exposure durations during day, night, and both day and night. A stand-alone application with Graphical User Interfaces (GUI) for calibrating, preprocessing, and classification of hyperspectral rice seed images is presented. The software application can be used for training two deep learning architectures for the classification of any type of hyperspectral seed images. The average overall classification accuracy of 91.33% and 89.50% is obtained for seed-based classification using 3D-CNN for five different treatments at each exposure duration and six different high temperature exposure durations for each treatment, respectively. The DNN gives an average accuracy of 94.83% and 91% for five different treatments at each exposure duration and six different high temperature exposure durations for each treatment, respectively. The accuracies obtained are higher than those presented in the literature for hyperspectral rice seed image classification. The HSI analysis presented here is on the Kitaake cultivar, which can be extended to study the temperature tolerance of other rice cultivars.

Ionizing radiation present in extraterrestrial environment is an important factor that affects plants grown in spaceflight. Pearson correlation-based gene regulatory network inferencing from transcriptional responses of the plant Arabidopsis thaliana L. grown in real and simulated spaceflight conditions acquired by GeneLab, followed by topological and spectral analysis of the networks is performed. Gene regulatory subnetworks are extracted for DNA damage response processes. Analysis of radiation-induced ATR/ATM protein–protein interactions in Arabidopsis reveals interaction profile similarities under low radiation doses suggesting novel mechanisms of DNA damage response involving non-radiation-induced genes regulating other stress responses in spaceflight. The Jaccard similarity index shows that the genes AT2G31320, AT4G21070, AT2G46610, and AT3G27060 perform similar functions under low doses of radiation. The incremental association Markov blanket method reveals non-radiation-induced genes linking DNA damage response to root growth and plant development. Eighteen radiation-induced genes and sixteen non-radiation-induced gene players have been identified from the ATR/ATM protein interaction complexes involved in heat, salt, water, osmotic stress responses, and plant organogenesis. Network analysis and logistic regression ranking detected AT3G27060, AT1G07500, AT5G66140, and AT3G21280 as key gene players involved in DNA repair processes. High atomic weight, high energy, and gamma photon radiation result in higher intensity of DNA damage response in the plant resulting in elevated values for several network measures such as spectral gap and girth. Nineteen flavonoid and carotenoid pigment activations involved in pigment biosynthesis processes are identified in low radiation dose total light spaceflight environment but are not found to have significant regulations under very high radiation dose environment.

Muscle atrophy is a side effect of several terrestrial diseases which also affects astronauts severely in space missions due to the reduced gravity in spaceflight. An integrative graph-theoretic network-based drug repurposing methodology quantifying the interplay of key gene regulations and protein–protein interactions in muscle atrophy conditions is presented. Transcriptomic datasets from mice in spaceflight from GeneLab have been extensively mined to extract the key genes that cause muscle atrophy in organ muscle tissues such as the thymus, liver, and spleen. Top muscle atrophy gene regulators are selected by Bayesian Markov blanket method and gene–disease knowledge graph is constructed using the scalable precision medicine knowledge engine. A deep graph neural network is trained for predicting links in the network. The top ranked diseases are identified and drugs are selected for repurposing using drug bank resource. A disease drug knowledge graph is constructed and the graph neural network is trained for predicting new drugs. The results are compared with machine learning methods such as random forest, and gradient boosting classifiers. Network measure based methods shows that preferential attachment has good performance for link prediction in both the gene–disease and disease–drug graphs. The receiver operating characteristic curves, and prediction accuracies for each method show that the random walk similarity measure and deep graph neural network outperforms the other methods. Several key target genes identified by the graph neural network are associated with diseases such as cancer, diabetes, and neural disorders. The novel link prediction approach applied to the disease drug knowledge graph identifies the Monoclonal Antibodies drug therapy as suitable candidate for drug repurposing for spaceflight induced microgravity. There are a total of 21 drugs identified as possible candidates for treating muscle atrophy. Graph neural network is a promising deep learning architecture for link prediction from gene–disease, and disease–drug networks.