Dr. Xosé R. Bustelo is a full research professor at the Spanish National Research Council (Consejo Superior de Investigaciones Científicas, CSIC), the main scientific institution of the Spanish central government. He also holds a principal investigator position at the Cancer Biomedical Research Center (Centro de Investigación Biomédica en Red de Cáncer, CIBERONC), a Spanish government-sponsored multicenter initiative aimed at promoting cooperative work in both basic and clinical research among the 50 top-rated cancer labs in Spain. Dr. Bustelo’s work has been traditionally focused on understanding the role of RHO GTPase-regulated pathways in both normal physiological processes and human disease.