Gnanendra Shanmugam

Dr. Gnanendra Shanmugam


Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2020 in Crystals
Verified
Journal Article
Open access
PDF file
PKPrasad Kumcham
Prasad Kumcham
Rajasekhara Reddy GutturuRajasekhara Reddy Gutturu
Rajasekhara Reddy Gutturu
RMRajesh Megala
Rajesh Megala
PBP. Reddi Babu
P. Reddi Babu
GSGnanendra Shanmugam
Gnanendra Shanmugam
KMKODURU MALLIKARJUNA
KODURU MALLIKARJUNA
With the rapid improvement of the global economy, the role of energy has become even more vital in the 21st century. In this regard, energy storage/conversion devices have become a major, worldwide research focus. In response to this, we have prepared two-dimensional (2D)-hierarchical sheet-like ZnCo2O4 microstructures for supercapacitor applications using a simple hydrothermal method. The 2D-hierarchical sheet-like morphologies with large surface area and smaller thickness enhanced the contact area of active material with the electrolyte, which increased the utilization rate. We investigated the electrochemical performance of sheet-like ZnCo2O4 microstructures while using Cyclic voltammetry (CV), Galvanostatic charge-discharge (GCD), and Electrochemical impedance spectroscopy (EIS) analysis. The electrochemical results demonstrated that the ZnCo2O4 electrode possesses 16.13 mF cm−2 of areal capacitance at 10 µA cm−2 of current density and outstanding cycling performance (170% of capacitance is retained after 1000 cycles at 500 µA cm−2). The high areal capacitance and outstanding cycling performance due to the unique sheet-like morphology of the ZnCo2O4 electrode makes it an excellent candidate for supercapacitor applications.

18 June 2019 in Applied Sciences
Verified
Journal Article
Open access
PDF file
PTPunitha Thambidurai
Punitha Thambidurai
VRVinodhini Raja
Vinodhini Raja
SSSaranya Ashokapuram Selvam
Saranya Ashokapuram Selvam
MKMoorthy Kannaiyan
Moorthy Kannaiyan
GSGnanendra Shanmugam
Gnanendra Shanmugam
The fungal keratitis (FK) infections that cause cornea inflammations are more virulent than other bacterial keratitis infections and remain one of the most ethereal and challenging infections for ophthalmologists to diagnose and treat. Thus, the urgency in understanding the current perspectives of antifungal agents and their interactions with novel therapeutic targets and the identification of novel anti-fungal agents are at the frontline of studies in the pharmaceutical industry. In this study, DNA dependent RNA polymerase was modelled and virtually screened against eight antifungal agents, and it was found that Itraconazole (−22.0427 kJ/mol), Ketoconazole (−20.2194 kJ/mol), and Voriconazole (−12.6388 kJ/mol) exhibited better binding interactions. further, the structural and electronic properties of Itraconazole calculated through density functional theory studies revealed the sites of chemical reactivity that are vital in the compounds for possible interactions with RNA polymerase (RNAP). Hence, this study explores the binding efficacies of various anti-fungal agents through docking studies and their chemical entities, which might pave a significant path for the design of novel anti-fungal agents against hyalohyphomycetes causing keratitis.