Klaus-Hendrik Wolf

Dr. Klaus-Hendrik Wolf

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Research Focus & Metrics

Academic Career Length

28Years (1999-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2011 in Methods of Information in Medicine
Verified
Journal Article
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ARA. Rehwald
A. Rehwald
KWKlaus-Hendrik Wolf
Klaus-Hendrik Wolf
MGMatthias Gietzelt
Matthias Gietzelt
GNG. Nemitz
G. Nemitz
HSH. Meyer zu Schwabedissen
H. Meyer zu Schwabedissen
MMMichael Marschollek
Michael Marschollek
Summary: Background: Falls are a predominant problem in our aging society, often leading to severe somatic and psychological consequences, and having an incidence of about 30% in the group of persons aged 65 years or above. In order to identify persons at risk, many assessment tools and tests have been developed, but most of these have to be conducted in a supervised setting and are dependent on an expert rater.Objectives: The overall aim of our research work is to develop an objective and unobtrusive method to determine individual fall risk based on the use of motion sensor data. The aims of our work for this paper are to derive a fall risk model based on sensor data that may potentially be measured during typical activities of daily life (aim #1), and to evaluate the resulting model with data from a one-year follow-up study (aim #2).Methods: A sample of n = 119 geriatric inpatients wore an accelerometer on the waist during a Timed ‘Up & Go’ test and a 20 m walk. Fifty patients were included in a one-year follow-up study, assessing fall events and scoring average physical activity at home in telephone interviews. The sensor data were processed to extract gait and dynamic balance parameters, from which four fall risk models – two classification trees and two logistic regression models – were computed: models CT#1 and SL#1 using accelerometer data only, models CT#2 and SL#2 including the physical activity score. The risk models were evaluated in a ten-times tenfold cross-validation procedure, calculating sensitivity (SENS), speci ficity (SPEC), positive and negative predictive values (PPV, NPV), classification accuracy, area under the curve (AUC) and the Brier score.Results: Both classification trees show a fair to good performance (models CT#1/ CT#2): SENS 74% / 58%, SPEC 96% / 82%, PPV 92% / 74%, NPV 77%/82%, accuracy 80% / 78%, AUC 0.83 / 0.87 and Brier scores 0.14 / 0.14. The logistic regression models (SL#1/ SL#2) perform worse: SENS 42% / 58%, SPEC 82% / 78%, PPV 62% / 65%, NPV 67% / 72%, accuracy 65% /70%, AUC 0.65 / 0.72 and Brier scores 0.23 / 0.21.Conclusions: Our results suggest that accelerometer data may be used to predict falls in an unsupervised setting. Furthermore, the parameters used for prediction are measurable with an unobtrusive sensor device during normal activities of daily living. These promising results have to be validated in a larger, long-term prospective trial.

1 May 2012 in Computer Methods and Programs in Biomedicine
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Journal Article
Closed access
WLWolfram Ludwig
Wolfram Ludwig
KWKlaus-Hendrik Wolf
Klaus-Hendrik Wolf
CDChristopher Duwenkamp
Christopher Duwenkamp
NGNathalie Gusew
Nathalie Gusew
NHNils Hellrung
Nils Hellrung
RHReinhold Haux
Reinhold Haux

25 August 2020 in JMIR Serious Games
Verified
Journal Article
Open access
BSBianca Steiner
Bianca Steiner
LELena Elgert
Lena Elgert
BSBirgit Saalfeld
Birgit Saalfeld
KWKlaus-Hendrik Wolf
Klaus-Hendrik Wolf
Background: Gamification has become increasingly important both in research and in practice. Particularly in long-term care processes, such as rehabilitation, playful concepts are gaining in importance to increase motivation and adherence. In addition to neurological diseases, this also affects the treatment of patients with musculoskeletal diseases such as shoulder disorders. Although it would be important to assist patients during more than one rehabilitation phase, it is hypothesized that existing systems only support a single phase. It is also unclear which game design elements are currently used in this context and how they are combined to achieve optimal positive effects on motivation. Objective: This scoping review aims to identify and analyze information and communication technologies that use game design elements to support the rehabilitation processes of patients with musculoskeletal diseases of the shoulder. The state of the art with regard to fields of application, game design elements, and motivation concepts will be determined. Methods: We conducted a scoping review to identify relevant application systems. The search was performed in 3 literature databases: PubMed, IEEE Xplore, and Scopus. Following the PICO (population, intervention, comparison, outcome) framework, keywords and Medical Subject Headings for shoulder, rehabilitation, and gamification were derived to define a suitable search term. Two independent reviewers, a physical therapist and a medical informatician, completed the search as specified by the search strategy. There was no restriction on year of publication. Data synthesis was done by deductive-inductive coding based on qualitative content analysis. Results: A total of 1994 articles were screened; 31 articles in English, published between 2006 and 2019, were included. Within, 27 application systems that support patients with musculoskeletal diseases of the shoulder in exercising, usually at home but also in inpatient or outpatient rehabilitation clinics, were described. Only 2 application systems carried out monitoring of adherence. Almost all were based on in-house developed software. The most frequently used game components were points, tasks, and avatars. More complex game components, such as collections and teams, were rarely used. When selecting game components, patient-specific characteristics, such as age and gender, were only considered in 2 application systems. Most were described as motivating, though an evaluation of motivational effects was usually not conducted. Conclusions: There are only a few application systems supporting patients with musculoskeletal diseases of the shoulder in rehabilitation by using game design elements. Almost all application systems are exergames for supporting self-exercising. Application systems for multiple rehabilitation phases seem to be nonexistent. It is also evident that only a few complex game design elements are used. Patient-specific characteristic are generally neglected when selecting and implementing game components. Consequently, a holistic approach to enhance adherence to rehabilitation is required supporting patients during the entire rehabilitation process by providing motivational game design elements based on patient-specific characteristics.

1 January 2016 in Methods of Information in Medicine
Verified
Journal Article
Closed access
PDF file
VHVincent Van Hees
Vincent Van Hees
KTKathrin Thaler-Kall
Kathrin Thaler-Kall
KWKlaus-Hendrik Wolf
Klaus-Hendrik Wolf
ABAttn: Jan Christian Brønd
Attn: Jan Christian Brønd
ABAlberto Bonomi
Alberto Bonomi
AHAlexander Horsch
Alexander Horsch
Summary: Objectives: Raw accelerometry is increasingly being used in physical activity research, but diversity in sensor design, attachment and signal processing challenges the comparability of research results. Therefore, efforts are needed to harmonize the methodology. In this article we reflect on how increased methodological harmonization may be achieved.Methods: The authors of this work convened for a two-day workshop (March 2014) themed on methodological harmonization of raw accelerometry. The discussions at the workshop were used as a basis for this review.Results: Key stakeholders were identified as manufacturers, method developers, method users (application), publishers, and funders. To facilitate methodological harmonization in raw accelerometry the following action points were proposed: i) Manufacturers are encouraged to provide a detailed specification of their sensors, ii) Each fundamental step of algorithms for processing raw accelerometer data should be documented, and ideally also motivated, to facilitate interpretation and discussion, iii) Algorithm developers and method users should be open about uncertainties in the description of data and the uncertainty of the inference itself, iv) All new algorithms which are pitched as “ready for implementation” should be shared with the community to facilitate replication and ongoing evaluation by independent groups, and v) A dynamic interaction between method stakeholders should be encouraged to facilitate a well-informed harmonization process.Conclusions: The workshop led to the iden -tification of a number of opportunities for harmonizing methodological practice. The discussion as well as the practical checklists proposed in this review should provide guidance for stakeholders on how to contribute to increased harmonization.

28 June 2011 in BMC Medical Informatics and Decision Making
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Journal Article
Open access
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MMMichael Marschollek
Michael Marschollek
ARAnja Rehwald
Anja Rehwald
KWKlaus-Hendrik Wolf
Klaus-Hendrik Wolf
MGMatthias Gietzelt
Matthias Gietzelt
GNGerhard Nemitz
Gerhard Nemitz
MSMareike Schulze
Mareike Schulze
Fall events contribute significantly to mortality, morbidity and costs in our ageing population. In order to identify persons at risk and to target preventive measures, many scores and assessment tools have been developed. These often require expertise and are costly to implement. Recent research investigates the use of wearable inertial sensors to provide objective data on motion features which can be used to assess individual fall risk automatically. So far it is unknown how well this new method performs in comparison with conventional fall risk assessment tools. The aim of our research is to compare the predictive performance of our new sensor-based method with conventional and established methods, based on prospective data.

1 July 2013 in Computer Methods and Programs in Biomedicine
Verified
Journal Article
Closed access
MGMatthias Gietzelt
Matthias Gietzelt
KWKlaus-Hendrik Wolf
Klaus-Hendrik Wolf
MMMichael Marschollek
Michael Marschollek
RHReinhold Haux
Reinhold Haux