The Mekong River Basin (MRB) is one of the significant river basins in the world. For political and economic reasons, it has remained mostly in its natural condition. However, with population increases and rapid industrial growth in the Mekong region, the river has recently become a hotbed of hydropower development projects. This study evaluated these changing hydrological conditions, primarily driven by climate as well as land use and land cover change between 1992 and 2015 and into the future. A 3% increase in croplands and a 1–2% decrease in grasslands, shrublands, and forests was evident in the basin. Similarly, an increase in temperature of 1–6 °C and in precipitation of 15% was projected for 2015–2099. These natural and climate-induced changes were incorporated into two hydrological models to evaluate impacts on water budget components, particularly streamflow. Wet season flows increased by up to 10%; no significant change in dry season flows under natural conditions was evident. Anomaly in streamflows due to climate change was present in the Chiang Saen and Luang Prabang, and the remaining flow stations showed up to a 5% increase. A coefficient of variation <1 suggested no major difference in flows between the pre- and post-development of hydropower projects. The results suggested an increasing trend in streamflow without the effect of dams, while the inclusion of a few major dams resulted in decreased river streamflow of 6% to 15% possibly due to irrigation diversions and climate change. However, these estimates fall within the range of uncertainties in natural climate variability and hydrological parameter estimations. This study offers insights into the relationship between biophysical and anthropogenic factors and highlights that management of the Mekong River is critical to optimally manage increased wet season flows and decreased dry season flows and handle irrigation diversions to meet the demand for food and energy production.

The Mekong River Basin is one of the world’s major transboundary basins. The hydrology, agriculture, ecology, and other watershed functions are constantly changing as a result of a variety of human activities carried out inside and by neighboring countries including China, Myanmar, Thailand, Laos, Cambodia, and Vietnam in order to meet increased food and water demands for an increasing population. The Mekong River, which provides irrigation and fishing for a population of over 60 million people, also has an estimated 88,000 MW of untapped hydropower potential. The construction of dams for energy supply has a wide-ranging impact on downstream reservoir regions, resulting in unprecedented changes in hydrologic functions, the environment, and people’s livelihoods. We present a holistic view of how external stressors such as climate change and variability, land cover, and land-use change affect supply and demand. We present an integrated modeling framework for analyzing the supply–demand scenarios and tradeoffs between different sectors. Specifically, we evaluated the impacts of future climate on irrigation, hydropower, and other needs in the basin through a feedback loop. We focused on hydrologic extremes to evaluate their impacts on the reservoir operations during flood and low flow events. The inflow is projected to change by +13% to −50% in the future, while a 0.25% (15.24 billion m³) reduction is projected for the net irrigation water requirement (NIWR). A unit percentage increase in irrigation demand will reduce energy generation by 0.15%, but climate change has a beneficial impact on dam performance with a predicted increase in energy generation and supply to all sectors. Flood events will cause excessive stress on reservoir operation to handle up to six times more flow volumes; however, the low-flow events will marginally affect the system. While the flow and storage rule curves consider both supply and demand, changing human water use comes second to changing climate or other biophysical considerations. This paper emphasizes the importance of considering feedback between climate–water–human society in the systems modeling framework in order to meet societal and ecological challenges. The findings will provide information on the risks and tradeoffs that exist in the water, energy, and food sectors of the basin.

The Mekong River basin supported a large population and ecosystem with abundant water and nutrient supply. However, the impoundments in the river can substantially alter the flow downstream and its timing. Using limited observations, this study demonstrated an approach to derive dam characteristics, including storage and flow rate, from remote-sensing-based data. Global Reservoir and Lake Monitor (GRLM), River-Lake Hydrology (RLH), and ICESat-GLAS, which generated altimetry from Jason series and inundation areas from Landsat 8, were used to estimate the reservoir surface area and change in storage over time. The inflow simulated by the variable infiltration capacity (VIC) model from 2008 to 2016 and the reservoir storage change were used in the mass balance equation to calculate outflows for three dams in the basin. Estimated reservoir total storage closely resembled the observed data, with a Nash-Sutcliffe efficiency and coefficient of determination more than 0.90 and 0.95, respectively. An average decrease of 55% in outflows was estimated during the wet season and an increase of up to 94% in the dry season for the Lam Pao. The estimated decrease in outflows during the wet season was 70% and 60% for Sirindhorn and Ubol Ratana, respectively, along with a 36% increase in the dry season for Sirindhorn. Basin-wide demand for evapotranspiration, about 935 mm, implicitly matched with the annual water diversion from 1000 to 2300 million m³. From the storage–discharge rating curves, minimum storage was also evident in the monsoon season (June–July), and it reached the highest in November. This study demonstrated the utility of remote sensing products to assess the impacts of dams on flows in the Mekong River basin.

Objective: To determine the factors associated with generalized anxiety disorders in patients presenting with polycystic ovarian syndrome. Study Design: Cross-sectional study. Place and Duration of Study: Gynecology and Psychiatric outpatient department of Pakistan Institute of Medical Sciences, SZABMU, Islamabad, from Jan to Jul 2016. Methodology: Patients presenting with polycystic ovarian syndrome were enrolled. Patients were selected from the gynaecological and Medicine department. Patient’s history was taken and diagnosis of generalized anxiety disorder was made utilising Generalized Anxiety Disorder-7. Patients having diabetes mellitus, hypertension, Cushing’s syndrome, hypoglycaemia, co-morbid psychiatric illnesses, history of psychiatric illness in past and family history of psychiatric illness were excluded from the study. Results: Among 105 patients with polycystic ovarian syndrome, 79 (75%) patients had no generalized anxiety disorders while, 26 (25%) had generalized anxiety disorders. 2 out of 12 (16.6%) patients of age range of 15-20 year had generalized anxiety disorders, 9 out of 63 14.2% patients having age 21-30 years had generalized anxiety disorders and 15 out of 30 (50%) patients having age 31-40 years age had generalized anxiety disorders. Chi-square test revealed age, education level and socioeconomic status has a significant association with presence of generalized anxiety disorder among patients of polycystic ovarian disorder (with p-value <0.05). Conclusion: Generalized anxiety disorder was common in patients with polycystic ovarian syndrome. Age, low education level and low socioeconomic status had a significant relationship with generalized anxiety disorder in polycystic ovarian syndrome patients.

A multi-model hydrological assessment in the Congo Basin is performed to assess water availability conditions for historical and future periods (1913–2099). With models limited by scarce in situ observations, a combination of GRACE satellite data and soil-moisture-based drought indices is shown to be capable of estimating water budget, streamflow, and drought and storage variability. Changes in land use and land cover played a role in modifying the hydrologic responses but were found to be within the uncertainties of other inputs, including weather, soil, and model parameters. Seasonal and annual variability in total water storage anomalies (TWSAs) and the modified Palmer drought severity index (MPDSI) display a good correlation with each other. A selected set of global climate models is used to characterize the future temperature and precipitation patterns. It is expected that subbasin-scale variability in future temperature and precipitation increases will result in increased evapotranspiration, decreased runoff, and more drought events in the Congo Basin.

The Mekong River Basin (MRB) is among one of the largest transboundary basins in the world. It shares its boundaries with six countries, viz. Chi |