A computerized detection system for the diagnosis of Schizophrenia (SZ) using a convolutional neural system is described in this study. Schizophrenia is an anomaly in the brain characterized by behavioral symptoms such as hallucinations and disorganized speech. Electroencephalograms (EEG) indicate brain disorders and are prominently used to study brain diseases. We collected EEG signals from 14 healthy subjects and 14 SZ patients and developed an eleven-layered convolutional neural network (CNN) model to analyze the signals. Conventional machine learning techniques are often laborious and subject to intra-observer variability. Deep learning algorithms that have the ability to automatically extract significant features and classify them are thus employed in this study. Features are extracted automatically at the convolution stage, with the most significant features extracted at the max-pooling stage, and the fully connected layer is utilized to classify the signals. The proposed model generated classification accuracies of 98.07% and 81.26% for non-subject based testing and subject based testing, respectively. The developed model can likely aid clinicians as a diagnostic tool to detect early stages of SZ.

Mental disorders (MDs) with onset in childhood or adolescence include neurodevelopmental disorders (NDDs) (intellectual disability and specific learning disabilities, such as dyslexia, attention deficit disorder (ADHD), and autism spectrum disorders (ASD)), as well as a broad range of mental health disorders (MHDs), including anxiety, depressive, stress-related and psychotic disorders. There is a high co-morbidity of NDDs and MHDs. Globally, there have been dramatic increases in the diagnosis of childhood-onset mental disorders, with a 2- to 3-fold rise in prevalence for several MHDs in the US over the past 20 years. Depending on the type of MD, children often grapple with social and communication deficits and difficulties adapting to changes in their environment, which can impact their ability to learn effectively. To improve outcomes for children, it is important to provide timely and effective interventions. This review summarises the range and effectiveness of AI-assisted tools, developed using machine learning models, which have been applied to address learning challenges in students with a range of NDDs. Our review summarises the evidence that AI tools can be successfully used to improve social interaction and supportive education. Based on the limitations of existing AI tools, we provide recommendations for the development of future AI tools with a focus on providing personalised learning for individuals with NDDs.

Sleep is vital for one’s general well-being, but it is often neglected, which has led to an increase in sleep disorders worldwide. Indicators of sleep disorders, such as sleep interruptions, extreme daytime drowsiness, or snoring, can be detected with sleep analysis. However, sleep analysis relies on visuals conducted by experts, and is susceptible to inter- and intra-observer variabilities. One way to overcome these limitations is to support experts with a programmed diagnostic tool (PDT) based on artificial intelligence for timely detection of sleep disturbances. Artificial intelligence technology, such as deep learning (DL), ensures that data are fully utilized with low to no information loss during training. This paper provides a comprehensive review of 36 studies, published between March 2013 and August 2020, which employed DL models to analyze overnight polysomnogram (PSG) recordings for the classification of sleep stages. Our analysis shows that more than half of the studies employed convolutional neural networks (CNNs) on electroencephalography (EEG) recordings for sleep stage classification and achieved high performance. Our study also underscores that CNN models, particularly one-dimensional CNN models, are advantageous in yielding higher accuracies for classification. More importantly, we noticed that EEG alone is not sufficient to achieve robust classification results. Future automated detection systems should consider other PSG recordings, such as electroencephalogram (EEG), electrooculogram (EOG), and electromyogram (EMG) signals, along with input from human experts, to achieve the required sleep stage classification robustness. Hence, for DL methods to be fully realized as a practical PDT for sleep stage scoring in clinical applications, inclusion of other PSG recordings, besides EEG recordings, is necessary. In this respect, our report includes methods published in the last decade, underscoring the use of DL models with other PSG recordings, for scoring of sleep stages.

Autistic individuals often have difficulties expressing or controlling emotions and have poor eye contact, among other symptoms. The prevalence of autism is increasing globally, posing a need to address this concern. Current diagnostic systems have particular limitations; hence, some individuals go undiagnosed or the diagnosis is delayed. In this study, an effective autism diagnostic system using electroencephalogram (EEG) signals, which are generated from electrical activity in the brain, was developed and characterized. The pre-processed signals were converted to two-dimensional images using the higher-order spectra (HOS) bispectrum. Nonlinear features were extracted thereafter, and then reduced using locality sensitivity discriminant analysis (LSDA). Significant features were selected from the condensed feature set using Student’s t-test, and were then input to different classifiers. The probabilistic neural network (PNN) classifier achieved the highest accuracy of 98.70% with just five features. Ten-fold cross-validation was employed to evaluate the performance of the classifier. It was shown that the developed system can be useful as a decision support tool to assist healthcare professionals in diagnosing autism.