Wei Ning Chen

Prof. Dr. Wei Ning Chen

School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 639798, Singapore
orcid

Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 October 2020 in Comprehensive Reviews in Food Science and Food Safety
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Journal Article
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KCKONG FEI CHAI
KONG FEI CHAI
AVAmanda Ying Hui Voo
Amanda Ying Hui Voo
WCWei Ning Chen
Wei Ning Chen
Bioactive peptides (BPs) are specific protein fragments that exert various beneficial effects on human bodies and ultimately influence health, depending on their structural properties and amino acid composition and sequences. By offering promising solutions to solve diverse health issues, the production, characterization, and applications of food‐derived BPs have drawn great interest in the current literature and are of particular interest to the food and pharmaceutical industries. The microbial fermentation of protein from various sources is indubitably a novel way to produce BPs with numerous beneficial health effects. Apart from its lower cost as compared to enzymes, the BPs produced from microbial fermentation can be purified without further hydrolysis. Despite these features, current literature shows dearth of information on the BPs produced from food via microbial fermentation. Hence, there is a strong necessity to explore the BPs obtained from food fermentation for the development of commercial nutraceuticals and functional foods. As such, this review focuses on the production of BPs from different food sources, including the extensively studied milk and milk products, with emphasis on microbial fermentation. The structure–activity (antihypertensive, antioxidant, antimicrobial, opiate‐like, anti‐inflammatory, anticancer/antiproliferative, antithrombotic, hypolipidemic, hypocholesterolemic, and mineral binding) relationship, potential applications, future development, and challenges of BPs obtained from food fermentation are also discussed.

27 April 2021 in EMBO Reports
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TTTing Shien Teng
Ting Shien Teng
YCYi Ling Chin
Yi Ling Chin
KCKONG FEI CHAI
KONG FEI CHAI
WCWei Ning Chen
Wei Ning Chen

3 December 2019 in Scientific Reports
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Journal Article
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XCXi Cui
Xi Cui
JLJaslyn J. L. Lee
Jaslyn J. L. Lee
WCWei Ning Chen
Wei Ning Chen
With increasing resource shortage and environmental pollution, it is preferable to utilize materials which are sustainable and biodegradable. Side-streams products generated from the food processing industry is one potential avenue that can be used in a wide range of applications. In this study, the food by-product okara was effectively reused for the extraction of cellulose. Then, the okara cellulose was further employed to fabricate cellulose hydrogels with favorable mechanical properties, biodegrablability, and non-cytotoxicity. The results showed that it could be biodegraded in soil within 28 days, and showed no cytotoxicity on NIH3T3 cells. As a proof of concept, a demostration of wearable and biocompatible strain sensor was achieved, which allowed a good and stable detection of human body movement behaviors. The okara-based hydrogels could provide an alternative platform for further physical and/or chemical modification towards tissue engineering, medical supplies, or smart biomimetic soft materials.

1 June 2019 in Journal of Functional Foods
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Journal Article
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RMRita Mark
Rita Mark
XLXiaomei Lyu
Xiaomei Lyu
JLJaslyn J.L. Lee
Jaslyn J.L. Lee
VSVictor Roberto Parra Sanchez
Victor Roberto Parra Sanchez
WCWei Ning Chen
Wei Ning Chen


3 November 2015 in Applied Microbiology and Biotechnology
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Journal Article
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JLJaslyn J.L Lee
Jaslyn J.L Lee
LCLiwei Chen
Liwei Chen
BCBin Cao
Bin Cao
WCWei Ning Chen
Wei Ning Chen