Protein‐fouling of membranes has negative effects on the wide applications of membrane materials, such as poly(vinylidene fluoride) (PVDF), poly(ether sulfone) (PES)/polysulfone (PSf). Zwitterionic materials have recently been used and identified from high throughput screens of large libraries of monomers to modify membranes due to their stable anti‐protein‐fouling properties. “Grafting from” polymerization is a technique involving monomers that are polymerized using an initiation reaction on the membrane surface. It is regarded as a simple, useful, and versatile modification approach to increase the anti‐fouling properties of a membrane. This strategy provides controllable introduction of graft chains with a high density and a long‐term chemical stability due to covalent attachment of graft chains. Graft density, chemistry, chain length, and conformation are all important parameters that need to be considered. This article presents a mini‐review of recent progress on the “grafting from” polymerization of zwitterionic monomers on the surfaces of PVDF and PES/PSf membranes, including an introduction of zwitterions and methods of graft polymerization. Various approaches such as free radical graft polymerization, photo‐induced graft polymerization, and plasma‐induced graft polymerization were compared based on uniformity and amount of grafted zwitterionic polymer, relative flux of modified membranes, simplicity and environment pollution of operation, and cost of technique. The application of different approaches and the performance of poly(zwitterion)‐grafted PVDF and PES/PSf membranes are summarized according to recent research. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 41781.