Many studies performed in the last decade have focused on the cutaneous microbiota. It has been shown that this microbiota plays a key role in skin homeostasis. Considered as “a second barrier” to the environment, it is very important to know how it reacts to exogenous aggressions. The cosmetics industry has a started to use this microbiota as a source of natural ingredients, particularly ones that confer photoprotection against ultraviolet (UV) rays. Interestingly, it has been demonstrated that bacterial molecules can block UV rays or reverse their harmful effects. Oral probiotics containing living microorganisms have also shown promising results in restoring skin homeostasis and reversing the negative effects of UV rays. Microbial-based active sunscreen compounds have huge potential for use as next-generation photoprotection products.

Our skin is daily aggressed by environmental factors and by certain personal care products (cleansers, deodorants, etc);Our obsession with cleanliness may do more harm than good for the balance of our skin’s microbiota and skin health. It has been observed that overcleanliness leads to an impairment of the skin barrier function and of skin microbiome balance leading to increased

Solar lentigo represent one of the most visible signs of photoaging reported on a majority of elderly people, increasing with age, the degree of exposure to UV and pollution. Epigenetic regulation is currently the most studied adaptive response to fight against skin pigmentation caused by UV exposure To reduce the appearance of UVB-induced pigmented spots, the goal of our study was