José L. Santos

Prof. José L. Santos

orcid

Research Focus & Metrics

Academic Career Length

35Years (1992-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2001 in Medicine & Science in Sports & Exercise
Verified
Journal Article
Closed access
MMMiguel A. Martinez-Gonzalez
Miguel A. Martinez-Gonzalez
JVJosé Javier Varo
José Javier Varo
JSJosé L. Santos
José L. Santos
JIJokin DE Irala
Jokin DE Irala
MGMichael Gibney
Michael Gibney
JMJ. Alfredo Martinez
J. Alfredo Martinez
MARTÍNEZ-GONZÁLEZ, M. A., J. J. VARO, J. L. SANTOS, J. DE IRALA, M. GIBNEY, J. KEARNEY, and J. A. MARTÍNEZ. Prevalence of physical activity during leisure time in the European Union. Med. Sci. Sports Exerc., Vol. 33, No. 7, 2001, pp. 1142–1146. Purpose To estimate the prevalence of physical activity during leisure time in adults from the 15 member states of the European Union and the relationship with sociodemographic variables. Methods A representative sample, with approximately 1000 adults, aged 15 and upward, was selected from each member state to complete a questionnaire on attitudes to physical activity, body weight, and health by a face-to-face interview, summing a total of 15,239 subjects. The amount of leisure-time physical activity was quantified by assigning metabolic equivalents (METs) to each activity. Multiple linear regression models with MET-h·wk−1 as the dependent variable were fitted. Results Northern European countries showed higher levels of physical activity than southern ones. The highest prevalence (91.9%) was found in Finland, and the lowest (40.7%) in Portugal. A higher percentage of men practiced any leisure-time physical activity and also showed higher mean of MET-h·wk−1. In both genders, the multivariate models showed a significant trend to higher leisure time activity in participants with higher educational levels and in nonsmokers. Also, an inverse association between body mass index and leisure-time physical activity was found. Conclusion The prevalence of any physical activity during leisure time in the adult European population was similar to the U.S. estimates. Nevertheless, the amount of activity is low, and a wide disparity between countries exists. To our knowledge, this is the first study determining the prevalence and amount of leisure-time physical activity, which is the first step to define strategies to persuade populations to increase their physical activity.

12 May 2016 in Lifestyle Genomics
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Journal Article
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LFLynnette R. Ferguson
Lynnette R. Ferguson
RCRaffaele De Caterina
Raffaele De Caterina
UGUlf Görman
Ulf Görman
HAHooman Allayee
Hooman Allayee
MKMartin Kohlmeier
Martin Kohlmeier
JMJ. Alfredo Martinez
J. Alfredo Martinez
Diversity in the genetic profile between individuals and specific ethnic groups affects nutrient requirements, metabolism and response to nutritional and dietary interventions. Indeed, individuals respond differently to lifestyle interventions (diet, physical activity, smoking, etc.). The sequencing of the human genome and subsequent increased knowledge regarding human genetic variation is contributing to the emergence of personalized nutrition. These advances in genetic science are raising numerous questions regarding the mode that precision nutrition can contribute solutions to emerging problems in public health, by reducing the risk and prevalence of nutrition-related diseases. Current views on personalized nutrition encompass omics technologies (nutrigenomics, transcriptomics, epigenomics, foodomics, metabolomics, metagenomics, etc.), functional food development and challenges related to legal and ethical aspects, application in clinical practice, and population scope, in terms of guidelines and epidemiological factors. In this context, precision nutrition can be considered as occurring at three levels: (1) conventional nutrition based on general guidelines for population groups by age, gender and social determinants; (2) individualized nutrition that adds phenotypic information about the person's current nutritional status (e.g. anthropometry, biochemical and metabolic analysis, physical activity, among others), and (3) genotype-directed nutrition based on rare or common gene variation. Research and appropriate translation into medical practice and dietary recommendations must be based on a solid foundation of knowledge derived from studies on nutrigenetics and nutrigenomics. A scientific society, such as the International Society of Nutrigenetics/Nutrigenomics (ISNN), internationally devoted to the study of nutrigenetics/nutrigenomics, can indeed serve the commendable roles of (1) promoting science and favoring scientific communication and (2) permanently working as a ‘clearing house' to prevent disqualifying logical jumps, correct or stop unwarranted claims, and prevent the creation of unwarranted expectations in patients and in the general public. In this statement, we are focusing on the scientific aspects of disciplines covering nutrigenetics and nutrigenomics issues. Genetic screening and the ethical, legal, social and economic aspects will be dealt with in subsequent statements of the Society.

11 October 2011 in Nutrition Journal
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Journal Article
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JSJosé L. Santos
José L. Santos
JHJudith A Ho-Urriola
Judith A Ho-Urriola
AGAndrea González
Andrea González
SSSusan V Smalley
Susan V Smalley
PDPatricia Domínguez-Vásquez
Patricia Domínguez-Vásquez
MHM Isabel Hodgson
M Isabel Hodgson
Inadequate eating behavior and physical inactivity contribute to the current epidemic of childhood obesity. The aim of this study was to assess the association between eating behavior scores and childhood obesity in Chilean children. We recruited 126 obese, 44 overweight and 124 normal-weight Chilean children (6-12 years-old; both genders) according to the International Obesity Task Force (IOTF) criteria. Eating behavior scores were calculated using the Child Eating Behavior Questionnaire (CEBQ). Factorial analysis in the culturally-adapted questionnaire for Chilean population was used to confirm the original eight-factor structure of CEBQ. The Cronbach's alpha statistic (>0.7 in most subscales) was used to assess internal consistency. Non-parametric methods were used to assess case-control associations. Eating behavior scores were strongly associated with childhood obesity in Chilean children. Childhood obesity was directly associated with high scores in the subscales "enjoyment of food" (P < 0.0001), "emotional overeating" (P < 0.001) and "food responsiveness" (P < 0.0001). Food-avoidant subscales "satiety responsiveness" and "slowness in eating" were inversely associated with childhood obesity (P < 0.001). There was a graded relation between the magnitude of these eating behavior scores across groups of normal-weight, overweight and obesity groups. Our study shows a strong and graded association between specific eating behavior scores and childhood obesity in Chile.

12 February 2015 in Critical Reviews in Food Science and Nutrition
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Journal Article
Closed access
Javier ParadaJavier Parada
Javier Parada
JSJosé L. Santos
José L. Santos
In real food, starch is usually forming part of a matrix with lipids and proteins. However, research on this ternary system and interactions between such food components has been scarce so far. The control of food microstructure is crucial to determine the product properties, including sensorial and nutritionals ones. This paper reviews the microstructural principles of interactions between starch, lipids, and proteins in foods as well as their effect on postprandial glycemic response, considering human intrinsic differences on postprandial glycemic responses. Several lines of research support the hypothesis that foods without rapidly digestible starch will not mandatorily generate the lowest postprandial glycemic response, highlighting that the full understanding of food microstructure, which modulates starch digestion, plays a key role on food design from a nutritional viewpoint.

1 November 1996
Verified
Journal Article
Closed access
CAC Albala
C Albala
MYM Yáñez
M Yáñez
EDE Devoto
E Devoto
CSC Sostin
C Sostin
LZL Zeballos
L Zeballos
JSJosé L. Santos
José L. Santos

1 June 2002 in Diabetologia
Verified
Journal Article
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TST. Sir-Petermann
T. Sir-Petermann
BABárbara Angel
Bárbara Angel
MMM. Maliqueo
M. Maliqueo
FCF. Carvajal
F. Carvajal
JSJosé L. Santos
José L. Santos
FPF. Pérez-Bravo
F. Pérez-Bravo