Infrastructure is a significant factor in economic growth for systems of government. In order to increase economic productivity, maintaining infrastructure quality is essential. One of the elements of infrastructure is roads. Roads are means which help local and national economies be more productive. Furthermore, road damage such as potholes, debris, or cracks is the cause of many on-road accidents that have cost the lives of many drivers. In this paper, we propose a system that uses Convolutional Neural Networks to detect road degradations without data pre-processing. We utilize the state-of-the-art object detection algorithm, YOLO detector for the system. First, we developed a basic system working on data collecting, pre-processing, and classification. Secondly, we improved the classification performance achieving 97.98% in the overall model testing, and then we utilized pixel-level classification and detection with a method called semantic segmentation. We were able to achieve decent results using this method to detect and classify four different classes (Manhole, Pothole, Blurred Crosswalk, Blurred Street Line). We trained a segmentation model that recognizes the four classes mentioned above and achieved great results with this model allowing the machine to effectively and correctly identify and classify our four classes in an image. Although we obtained excellent accuracy from the detectors, these do not perform particularly well on embedded systems due to their network size. Therefore, we opted for a smaller, less accurate detector that will run in real time on a cheap embedded system, like the Google Coral Dev Board, without needing a powerful and expensive GPU.

During every Atlantic hurricane season, storms represent a constant risk to Texan coastal communities and other communities along the Atlantic coast of the United States. A storm surge refers to the abnormal rise of sea water level due to hurricanes and storms; traditionally, hurricane storm surge predictions are generated using complex numerical models that require high amounts of computing power to be run, which grow proportionally with the extent of the area covered by the model. In this work, a machine-learning-based storm surge forecasting model for the Lower Laguna Madre is implemented. The model considers gridded forecasted weather data on winds and atmospheric pressure over the Gulf of Mexico, as well as previous sea levels obtained from a Laguna Madre ocean circulation numerical model. Using architectures such as Convolutional Neural Networks (CNN) and Long Short-Term Memory (LSTM) combined, the resulting model is capable of identifying upcoming hurricanes and predicting storm surges, as well as normal conditions in several locations along the Lower Laguna Madre. Overall, the model is able to predict storm surge peaks with an average difference of 0.04 m when compared with a numerical model and an average RMSE of 0.08 for normal conditions and 0.09 for storm surge conditions.

Over the past few years, it has been established that a number of long intergenic non-coding RNAs (lincRNAs) are linked to a wide variety of human diseases. The relationship among many other lincRNAs still remains as puzzle. Validation of such link between the two entities through biological experiments is expensive. However, piles of information about the two are becoming available, thanks to the High Throughput Sequencing (HTS) platforms, Genome Wide Association Studies (GWAS), etc, thereby opening opportunity for cutting-edge machine learning and data mining approaches. However, there are only a few in silico lincRNA-disease association inference tools available to date, and none of these utilizes side information of both the entities. The recently developed Inductive Matrix Completion (IMC) technique provides a recommendation platform among two entities considering respective side information. But, the formulation of IMC is incapable of handling noise and outliers that may present in the dataset, while data sparsity consideration is another issue with the standard IMC method. Thus, a robust version of IMC is needed that can solve these two issues. As a remedy, in this paper, we propose Robust Inductive Matrix Completion (RIMC) using $l_{2,1}$ norm loss function as well as $l_{2,1}$ norm based regularization. We applied RIMC to the available association data between human lincRNAs and OMIM disease phenotypes as well as a diverse set of side information about the lincRNAs and the diseases. Our method performs better than the state-of-the-art methods in terms of $precision@k$ and $recall@k$ at the top-$k$ disease prioritization to the subject lincRNAs. We also demonstrate that RIMC is equally effective for querying about novel lincRNAs, as well as predicting rank of a newly known disease for a set of well-characterized lincRNAs.

Inferring gene regulatory networks is one of the most interesting research areas in the systems biology. Many inference methods have been developed by using a variety of computational models and approaches. However, there are two issues to solve. First, depending on the structural or computational model of inference method, the results tend to be inconsistent due to innately different advantages and limitations of the methods. Therefore the combination of dissimilar approaches is demanded as an alternative way in order to overcome the limitations of standalone methods through complementary integration. Second, sparse linear regression that is penalized by the regularization parameter (lasso) and bootstrapping-based sparse linear regression methods were suggested in state of the art methods for network inference but they are not effective for a small sample size data and also a true regulator could be missed if the target gene is strongly affected by an indirect regulator with high correlation or another true regulator. We present two novel network inference methods based on the integration of three different criteria, (i) z-score to measure the variation of gene expression from knockout data, (ii) mutual information for the dependency between two genes, and (iii) linear regression-based feature selection. Based on these criterion, we propose a lasso-based random feature selection algorithm (LARF) to achieve better performance overcoming the limitations of bootstrapping as mentioned above. In this work, there are three main contributions. First, our z score-based method to measure gene expression variations from knockout data is more effective than similar criteria of related works. Second, we confirmed that the true regulator selection can be effectively improved by LARF. Lastly, we verified that an integrative approach can clearly outperform a single method when two different methods are effectively jointed. In the experiments, our methods were validated by outperforming the state of the art methods on DREAM challenge data, and then LARF was applied to inferences of gene regulatory network associated with psychiatric disorders.

Utilizing computer vision and the latest technological advancements, in this study, we developed a honey bee monitoring system that aims to enhance our understanding of Colony Collapse Disorder, honey bee behavior, population decline, and overall hive health. The system is positioned at the hive entrance providing real-time data, enabling beekeepers to closely monitor the hive's activity and health through an account-based website. Using machine learning, our monitoring system can accurately track honey bees, monitor pollen-gathering activity, and detect Varroa mites, all without causing any disruption to the honey bees. Moreover, we have ensured that the development of this monitoring system utilizes cost-effective technology, making it accessible to apiaries of various scales, including hobbyists, commercial beekeeping businesses, and researchers. The inference models used to detect honey bees, pollen, and mites are based on the YOLOv7-tiny architecture trained with our own data. The F1-score for honey bee model recognition is 0.95 and the precision and recall value is 0.981. For our pollen and mite object detection model F1-score is 0.95 and the precision and recall value is 0.821 for pollen and 0.996 for "mite". The overall performance of our IntelliBeeHive system demonstrates its effectiveness in monitoring the honey bee's activity, achieving an accuracy of 96.28 % in tracking and our pollen model achieved a F1-score of 0.831.