Low-dose CT is an effective solution to alleviate radiation risk to patients, it also introduces additional noise and streak artifacts. In order to maintain a high image quality for low-dose scanned CT data, we propose a post-processing method based on deep learning and using 2-D and 3-D residual convolutional networks. Experimental results and comparisons with other competing methods show that the proposed approach can effectively reduce the low-dose noise and artifacts while preserving tissue details. It is also pointed out that the 3-D model can achieve better performance in both edge-preservation and noise-artifact suppression. Factors that may influence the model performance, such as model width, depth, and dropout, are also examined.

Nowadays, chaos-based image encryption is recognized as an effective choice in secure communications. This paper proposes a novel approach which uses bit-pair level XOR, add, rotation from top to bottom and enhances diffusion with pixel level XOR operator from the lower right corner to the upper left corner. Due to the bit-pair level encryption, the proposed scheme has ensured great security and high encryption speed. The chaotic series employed for encryption are obtained from the modified pulse-coupled spiking neurons circuit map. It is suitable for using in encryption because of its abundant parameters: wide chaotic range, ergodicity, complexity and high sensitivity. Furthermore, the results show the superiority of this scheme compared to other four methods in terms of robustness to differential attack.

In this work, we address the task of few-shot medical image segmentation (MIS) with a novel proposed framework based on the learning registration to learn segmentation (LRLS) paradigm. To cope with the limitations of lack of authenticity, diversity, and robustness in the existing LRLS frameworks, we propose the better registration better segmentation (BRBS) framework with three main contributions that are experimentally shown to have substantial practical merit. First, we improve the authenticity in the registration-based generation program and propose the knowledge consistency constraint strategy that constrains the registration network to learn according to the domain knowledge. It brings the semantic-aligned and topology-preserved registration, thus allowing the generation program to output new data with great space and style authenticity. Second, we deeply studied the diversity of the generation process and propose the space-style sampling program, which introduces the modeling of the transformation path of style and space change between few atlases and numerous unlabeled images into the generation program. Therefore, the sampling on the transformation paths provides much more diverse space and style features to the generated data effectively improving the diversity. Third, we first highlight the robustness in the learning of segmentation in the LRLS paradigm and propose the mix misalignment regularization, which simulates the misalignment distortion and constrains the network to reduce the fitting degree of misaligned regions. Therefore, it builds regularization for these regions improving the robustness of segmentation learning. Without any bells and whistles, our approach achieves a new state-of-the-art performance in few-shot MIS on two challenging tasks that outperform the existing LRLS-based few-shot methods. We believe that this novel and effective framework will provide a powerful few-shot benchmark for the field of medical image and efficiently reduce the costs of medical image research. All of our code will be made publicly available online.

Objective: The present study introduces a fractional wavelet scattering network (FrScatNet), which is a generalized translation invariant version of the classical wavelet scattering network (ScatNet). Methods: In our approach, the FrScatNet is constructed based on the fractional wavelet transform (FRWT). The fractional scattering coefficients are iteratively computed using FRWTs and modulus operators. The feature vectors constructed by fractional scattering coefficients are usually used for signal classification. In this work, an application example of FrScatNet is provided in order to assess its performance on pathological images. Firstly, the FrScatNet extracts feature vectors from patches of the original histological images under different orders. Then we classify those patches into target (benign or malignant) and background groups. And the FrScatNet property is analyzed by comparing error rates computed from different fractional orders respectively. Based on the above pathological image classification, a gland segmentation algorithm is proposed by combining the boundary information and the gland location. Results: The error rates for different fractional orders of FrScatNet are examined and show that the classification accuracy is significantly improved in fractional scattering domain. We also compare the FrScatNet based gland segmentation method with those proposed in the 2015 MICCAI Gland Segmentation Challenge and our method achieves comparable results. Conclusion: The FrScatNet is shown to achieve accurate and robust results. More stable and discriminative fractional scattering coefficients for different are obtained by the FrScatNet in this work. Significance: The added fractional order parameter is then able to analyze the signal in the fractional scattering domain.

For the feature extraction of red–blue–green (RGB) colour images, researchers usually deal with R, G and B channels separately to obtain three feature vectors, and then combine them together to obtain a long real feature vector. This approach does not exploit the relationships between the three channels of the colour images. Recently, attention has been paid to quaternion features, which take the relationships between channels into consideration and seem to be more suitable for representing colour images. However, there are only a few quaternion classifiers for dealing with quaternion features. To meet this requirement, a new quaternion classifier, namely, the quaternion softmax classifier is proposed, which is an extended version of the conventional softmax classifier generally defined in the complex (or real) domain. The proposed quaternion softmax classifier is applied to two of the most common quaternion features, that is, the quaternion principal components analysis feature and the colour image pixel feature. The experimental results show that the proposed method performs better than the quaternion back propagation neural network in terms of accuracy and convergence rate.