Lucia Cugusi

Lucia Cugusi

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Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2018 in Critical Reviews in Oncology/Hematology
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Journal Article
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FDFEDERICA DUREGON
FEDERICA DUREGON
BVBarbara Vendramin
Barbara Vendramin
VBValentina Bullo
Valentina Bullo
SGStefano Gobbo
Stefano Gobbo
LCLucia Cugusi
Lucia Cugusi
AEAndrea Ermolao
Andrea Ermolao

15 October 2015 in NeuroRehabilitation
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LCLucia Cugusi
Lucia Cugusi
PSPaolo Solla
Paolo Solla
RSRoberto Serpe
Roberto Serpe
TCTatiana Carzedda
Tatiana Carzedda
LPLuisa Piras
Luisa Piras
GMGiuseppe Mercuro
Giuseppe Mercuro
BACKGROUND: Several studies have clearly shown that physical exercise can reduce the progression of motor symptoms in Parkinson’s Disease (PD). However, little is known about the effects of a Nordic Walking (NW) program in PD patients. OBJECTIVE: To determine the effects of a NW program on motor and non-motor symptoms, functional performances and body composition in PD patients. METHODS: Twenty PD patients (16M, 4F, 67.3±7.8 years) were enrolled and randomly assigned to NW group (NWg, n = 10) and Control group (Cg, n = 10). The training consisted in 2 sessions per week for 12 weeks. Training effects were assessed by functional and instrumental tests and motor and non-motor symptoms were assessed by UPDRS-III, Hoehn and Yahr scale, PD Fatigue Scale, Beck Depression Inventory-II, Starkstein Apathy Scale, and Non-Motor Symptoms Scale. RESULTS: Significant changes in resting HR, in walked distance ( p < 0.05), and in lower limbs muscles strength ( p < 0.005) were observed in NWg. Both balance abilities and safety with mobility were increased ( p < 0.005). Significant variations in some circumferences and body composition were registered. Finally, a significant improvement in motor and non-motor symptoms was detected: UPDRS-III, HY scale, PFS-16, BDI-II, SAS, NMSS. CONCLUSIONS: A tailored exercise program including NW proved to be an effective way to improve daily activities and both motor and non-motor symptoms in PD patients.

1 March 2019 in The Journal of Alternative and Complementary Medicine
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Journal Article
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PSPaolo Solla
Paolo Solla
LCLucia Cugusi
Lucia Cugusi
MBMatilde Bertoli
Matilde Bertoli
ACAndrea Cereatti
Andrea Cereatti
UCUgo Della Croce
Ugo Della Croce
GMGiuseppe Mercuro
Giuseppe Mercuro
Objectives: Among different exercise models proposed for individuals with Parkinson's disease (IwPD), the popularity of traditional forms of dance is increasing. The aim of this study was to evaluate the effects of Sardinian folk dance (Ballu Sardu, BS) on functional performance and motor and nonmotor symptoms in IwPD. Design: Single-blind, randomized controlled pilot trial. Settings: Outpatient health clinic. Subjects and interventions: Twenty IwPD (13M, 7F; 67.4 ± 6.1 years) were randomly assigned to BS (n = 10) or usual care (n = 10). The dance program consisted of two sessions/week, 90-min/class, for 12 weeks. Outcome measures: Motor and nonmotor symptoms, as well as functional performance, were evaluated using different questionnaires and tests such as the Unified Parkinson's Disease Rating Scale Part-III (UPDRS-III), 6-min walking test (6MWT), Berg Balance Scale (BBS), Timed Up-and-Go (TUG) test, Five Times Sit-to-Stand Test (FTSST), Back Scratch Test (BST), Sit-and-Reach Test (SRT), instrumented gait analysis, Parkinson's Disease Fatigue Scale (PFS-16), Beck Depression Inventory, Starkstein Apathy Scale (SAS), and Montreal Cognitive Assessment (MOCA) scale. Results: Repeated-measures analysis of variance revealed significant Time × Group interactions for UPDRS-III and functional variables such as the 6MWT, BBS, FTSST, TUG (all, p < 0.001), BST (p = 0.04), and gait analysis parameters (stride length, p = 0.031; gait speed, p = 0.049; and gait fatigue index (GFI), p = 0.005). For nonmotor symptoms, significant Time × Group interactions for depression (p < 0.001), apathy (p = 0.016), and MOCA scores (p = 0.012) were observed. Of note, for GFI and SAS, the BS group only showed a trend toward improvement, while the condition of the controls worsened significantly. No between-group differences were observed for SRT and PFS-16. Conclusions: BS is an enjoyable activity, which has been proved to be superior to usual care alone in inducing changes in different motor and nonmotor symptoms associated with PD. Results show that BS can be considered a safe tool for contrasting impairments observed in IwPD due to the intrinsic nature of the neurodegenerative disease.

1 April 2018 in Rejuvenation Research
Verified
Journal Article
Closed access
VBValentina Bullo
Valentina Bullo
SGStefano Gobbo
Stefano Gobbo
BVBarbara Vendramin
Barbara Vendramin
FDFEDERICA DUREGON
FEDERICA DUREGON
LCLucia Cugusi
Lucia Cugusi
AEAndrea Ermolao
Andrea Ermolao
The aim of this systematic review and meta-analysis was to summarize and analyze the effects of Nordic Walking on physical fitness, body composition, and quality of life in the elderly. Keyword “Nordic Walking” associated with “elderly” AND/OR “aging” AND/OR “old subjects” AND/OR “aged” AND/OR “older adults” were used in the online database MEDLINE, Embase, PubMed, Scopus, PsycINFO, and SPORTDiscus. Only studies written in English language and published in peer-reviewed journals were considered. A meta-analysis was performed and effect sizes calculated. Fifteen studies were identified; age of participants ranged from 60 to 92 years old. Comparing with a sedentary group, effect sizes showed that Nordic Walking was able to improve dynamic balance (0.30), functional balance (0.62), muscle strength of upper (0.66) and lower limbs (0.43), aerobic capacity (0.92), cardiovascular outcomes (0.23), body composition (0.30), and lipid profile (0.67). It seemed that Nordic Walking had a negative effect on static balance (−0.72). Comparing with a walking (alone) training, effect sizes showed that Nordic Walking improved the dynamic balance (0.30), flexibility of the lower body (0.47), and quality of life (0.53). Walking training was more effective in improving aerobic capacity (−0.21). Comparing Nordic Walking with resistance training, effect sizes showed that Nordic Walking improved dynamic balance (0.33), muscle strength of the lower body (0.39), aerobic capacity (0.75), flexibility of the upper body (0.41), and the quality of life (0.93). Nordic Walking can be considered as a safe and accessible form of aerobic exercise for the elderly population, able to improve cardiovascular outcomes, muscle strength, balance ability, and quality of life.

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Antonella MeloniAntonella Meloni
Antonella Meloni
Christian Cadeddu DessalviChristian Cadeddu Dessalvi
Christian Cadeddu Dessalvi
LCLucia Cugusi
Lucia Cugusi
MDMaria Pia Donataccio
Maria Pia Donataccio
MDMartino Deidda
Martino Deidda
SMSilvia Maffei
Silvia Maffei
Metabolic syndrome (Mets) is a clinical condition characterized by a cluster of major risk factors for cardiovascular disease (CVD) and type 2 diabetes: proatherogenic dyslipidemia, elevated blood pressure, dysglycemia, and abdominal obesity. Each risk factor has an independent effect, but, when aggregated, they become synergistic, doubling the risk of developing cardiovascular diseases and causing a 1.5-fold increase in all-cause mortality. We will highlight gender differences in the epidemiology, etiology, pathophysiology, and clinical expression of the aforementioned Mets components. Moreover, we will discuss gender differences in new biochemical markers of metabolic syndrome and cardiovascular risk.

1 June 2017 in Neuroscience
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Journal Article
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AMAndrea Manca
Andrea Manca
GMGianluca Martinez
Gianluca Martinez
LCLucia Cugusi
Lucia Cugusi
DDDaniele Dragone
Daniele Dragone
ZDZeevi Dvir
Zeevi Dvir
FDFranca Deriu
Franca Deriu