Prof. Dr. Kwangha Lee

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Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

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1 October 2018 in Journal of Critical Care

Journal Article

Combined vitamin C, hydrocortisone, and thiamine therapy for patients with severe pneumonia who were admitted to the intensive care unit: Propensity score-based analysis of a before-after cohort study

To evaluate the efficacy of combined vitamin C, hydrocortisone, and thiamine in patients with severe pneumonia. All consecutive patients with severe pneumonia who were treated with the vitamin C protocol (6 g of vitamin C per day) in June 2017-January 2018 (n = 53) were compared to all consecutive patients with severe pneumonia who were treated in June 2016-January 2017 (n = 46). Propensity score analysis was used to adjust for potential baseline differences between the groups. In the propensity-matched cohort (n = 36/group), the treated patients had significantly less hospital mortality than the control group (17% vs. 39%; P = 0.04). The vitamin C protocol associated independently with decreased mortality in propensity score-adjusted analysis (adjusted odds ratio = 0.15, 95% confidence interval = 0.04-0.56, P = 0.005). Relative to the control group, the treatment group had a significantly higher median improvement in the radiologic score at day 7 compared with baseline (4 vs. 2; P = 0.045). The vitamin C protocol did not increase the rates of acute kidney injury or superinfection. Combined vitamin C, hydrocortisone, and thiamine therapy may benefit patients with severe pneumonia.

26 June 2023 in Respiratory Medicine

Journal Article

Clinical outcomes of transbronchial cryobiopsy using a 1.1-mm diameter cryoprobe for peripheral lung lesions - A prospective pilot study

Wan Ho Yoo

1 December 2013 in Cancer Research and Treatment

Journal Article

Sarcoidosis Mimicking Cancer Metastasis Following Chemotherapy for Ovarian Cancer

Mi Hyun Kim

Kwangha Lee

Ki Uk Kim

Hye-Kyung Park

Min Ki Lee

Dong Soo Suh

We report on a rare case of sarcoidosis that developed after chemotherapy for ovarian cancer, and mimicked a cancer metastasis. A 52-year-old female diagnosed with stage III ovarian cancer underwent curative surgery and postoperative chemotherapy. Four months later, her whole-body positron emission tomography and computed tomography (CT) scan showed high uptake in the mediastinal lymph nodes, and ovarian cancer recurrence was suspected. Biopsy of the mediastinal lymph nodes and subcutaneous nodules revealed noncaseating granulomas. These lesions resolved spontaneously without treatment; however, newly developed perilymphatic and centrilobular nodules were observed on follow-up chest CT. Surgical biopsy of these lesions also showed noncaseating granulomas. She was finally diagnosed with sarcoidosis.

1 January 2014 in BioMed Research International

Journal Article

Misidentification ofCandida guilliermondiiasC. famataamong Strains Isolated from Blood Cultures by the VITEK 2 System

Si Hyun Kim

Jeong Hwan Shin

Jeong Ha Mok

Shine Young Kim

Sae Am Song

Kwangha Lee

Introduction. The aim of this study was to differentiate betweenCandida famataandCandida guilliermondiicorrectly by using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) and gene sequencing.Methods. Twenty-eightCandidastrains from blood cultures that had been identified asC. famata(

N = 25

),C. famata/C. guilliermondii(

N = 2

), andC. guilliermondii(

N = 1

) by the VITEK 2 system using the YST ID card were included. We identified these strains by MALDI-TOF MS and gene sequencing using the 28S rRNA andITSgenes and compared the results with those obtained by the VITEK 2 system.Results. All 28 isolates were finally identified asC. guilliermondii.Sequencing analysis of the 28S rRNA gene showed 99.80%–100% similarity withC. guilliermondiifor all 28 strains. TheITSgene sequencing of the strains showed 98.34%–100% homology withC. guilliermondii.By MALDI-TOF, we could correctly identify 21 (75%) of 28C. guilliermondiiisolates.Conclusion. We should suspect misidentification whenC. famatais reported by the VITEK 2 system, and we always should keep in mind the possibility of misidentification of any organism when an uncommon species is reported.

1 January 2012 in Tuberculosis and Respiratory Diseases

Journal Article

Cardiopulmonary Resuscitation: New Concept

Kwangha Lee

Lee K. Tuberc Respir Dis. 2012 May;72(5):401-408. http://dx.doi.org/10.4046/trd.2012.72.5.401

1 June 2016 in Journal of Critical Care

Journal Article

Clinical application of the ProVent score in Korean patients requiring prolonged mechanical ventilation: A 10-year experience in a university-affiliated tertiary hospital

Jeong Ha Mok

Yang Hee Kim

Eun Suk Jeong

Jung Seop Eom

Mi Hyun Kim

Kwangha Lee

About Me

Kwangha Lee M.D. Ph.D. Professor, Department of Internal Medicine, Pusan National University School of Medicine, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Pusan National University Hospital. Chief, Respiratory Intensive Care Unit, Pusan National University Hospital. Educational Background 2008.3–2014.2: Doctor of Philosophy of Medicine, Internal Medicine University of Ulsan College of Medicine. 2005.3–2007.2: Master of Science, Internal Medicine University of Ulsan College of Medicine. 1993.3–1999.2: Bachelor of Medicine, Chung-Ang University College of Medicine. Work Experience: 2023.9–Present: Professor. 2018.4–2023.8: Associate Professor. 2014.4–2018.3: Assistant Professor, Department of Internal Medicine, Pusan National University School of Medicine, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Pusan National University Hospital. 2010.3–2014.3: Clinical Assistant Professor, Department of Internal Medicine, Pusan National University Hospital. Personal Interests: Pulmonary and Critical Care Medicine Memberships of Professional Societies: Member of the Korean Association of Internal Medicine; Member of the Korean Academy of Tuberculosis and Respiratory Diseases; Member of the Asian Pacific Society of Respirology; Member of the Korean Society of Critical Care Medicine.

Prof. Dr. Kwangha Lee

Prof. Dr. Kwangha Lee

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