Wenjie Sun

Prof. Dr. Wenjie Sun

School of Public Health and Tropical Medicine, Tulane University, 1440 Canal Street, New Orleans, LA 70112, USA
orcid

Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 February 2016 in Environmental Health
Verified
Journal Article
Open access
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CFCindy Feng
Cindy Feng
JLJian Li
Jian Li
WSWenjie Sun
Wenjie Sun
YZYi Zhang
Yi Zhang
QWQuanyi Wang
Quanyi Wang
Air pollution in Beijing, especially PM2.5, has received increasing attention in the past years. Although exposure to PM2.5 has been linked to many health issues, few studies have quantified the impact of PM2.5 on the risk of influenza-like illness (ILI). The aim of our study is to investigate the association between daily PM2.5 and ILI risk in Beijing, by means of a generalized additive model. Daily PM2.5, meteorological factors, and influenza-like illness (ILI) counts during January 1, 2008 to December 31, 2014 were retrieved. An inverse Gaussian generalized additive model with log link function was used to flexibly model the nonlinear relationship between the PM2.5 (single- and multiday lagged exposure) and ILI risk, adjusted for the weather conditions, seasonal and year trends. We also assessed if the effect of PM2.5 differs during flu season versus non-flu season by including the interaction term between PM2.5 and flu season in the model. Furthermore, a stratified analysis by age groups was conducted to investigate how the effect of PM2.5 differs across age groups. Our findings suggested a strong positive relationships between PM2.5 and ILI risk at the flu season (October-April) (p-value < 0.001), after adjusting for the effects of ambient daily temperature and humidity, month and year; whereas no significant association was identified at the non-flu season (May-September) (p-value = 0.174). A short term delayed effect of PM2.5 was also identified with 2-day moving average (current day to the previous day) of PM2.5 yielding the best predictive power. Furthermore, PM2.5 was strongly associated with ILI risk across all age groups (p-value < 0.001) at the flu season, but the effect was the most pronounced among adults (age 25–59), followed by young adults (age 15–24), school children (age 5–14) and the elderly (age 60+) and the effect of PM2.5 was the least pronounced for children under 5 years of age (age < 5). Ambient PM2.5 concentrations were significantly associated with ILI risk in Beijing at the flu season and the effect of PM2.5 differed across age groups, in Beijing, China.

XLXiaoping Luo
Xiaoping Luo
TLTingting Liu
Tingting Liu
XYXiaojing Yuan
Xiaojing Yuan
SGSong Ge
Song Ge
JYJing Yang
Jing Yang
WSWenjie Sun
Wenjie Sun
Diabetes is a major public health problem in China. Diabetes self-management is critical for patients to achieved better health outcomes, however, previous studies have shown suboptimal diabetes self-management performance. We conducted a systematic review and meta-analysis to identify factors associated with diabetes self-management in Chinese adults. The results showed that confrontation, resignation, overall health beliefs, perceived susceptibility, perceived barriers, and self-efficacy were factors associated with overall diabetes self-management performance and six aspects of diabetes self-management behaviors. There is some limited evidence to suggest that provider-patient communication, married individuals, higher educational level, and higher household income level may also be linked to better diabetes self-management practice. Having healthcare insurance and utilizing chronic illness resources generally appeared to have a favorable effect on diabetes self-management performance. In addition, there were a number of factors for which the evidence is too limited to be able to ascertain its strength of association with diabetes self-management practice. The findings of this review suggest that diabetes self-management behaviors are affected by a wide range of personal and environmental factors, which allow health care providers to develop theory-based strategies to improve diabetes-self-management behaviors in this population.

20 February 2015 in Critical Care
Verified
Journal Article
Open access
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YZYi Zhang
Yi Zhang
WSWenjie Sun
Wenjie Sun
ESErik Svendsen
Erik Svendsen
STSong Tang
Song Tang
RMRaina MacIntyre
Raina MacIntyre
QWQuanyi Wang
Quanyi Wang
Introduction: Corticosteroids are used empirically in influenza A (H1N1) treatment despite lack of clear evidence for effective treatment. This study aims to assess the efficacy of corticosteroids treatment for H1N1 infection.Methods: Systematic review and meta-analysis were used to estimate the efficacy of corticosteroids for the prevention of mortality in H1N1 infection. Databases searched included MEDLINE, EMBASE, PubMed, Cochrane Central Register of Controlled Clinical Trials and so on, and bibliographies of retrieved articles, from April 2009 to October 2014. We included both cohort studies and case-control studies reported in English or Chinese that compared treatment effects between corticosteroids and non-corticosteroids therapy in inpatients with H1N1 virus infection. Cohort studies employed mortality as outcome, and case-control studies employed deaths as cases and survivors as controls; both were assessed in this meta-analysis.Results: In total twenty-three eligible studies were included. Both cohort studies (nine studies, n = 1,405) and case-control studies (14 studies, n = 4,700) showed a similar trend toward increased mortality (cohort studies relative risk was 1.85 with 95% confidence interval (CI) 1.46 to 2.33; case-control studies odds ratio was 4.22 with 95% CI 3.10 to 5.76). The results from both subgroup analyses and sensitive analyses were consistent with each other, showing that steroid treatment is associated with mortality. However, considering the fact that corticosteroids were tend to be used in sickest case-patients and heterogeneity was observed between studies, we cannot make a solid conclusion.Conclusions: Available evidence did not support the use of corticosteroids as standard care for patients with severe influenza. We conclude that further research is required.

2 August 2020 in Journal of Medical Virology
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GHGuiqing He
Guiqing He
Jing WuJing Wu
Jing Wu
JSJichan Shi
Jichan Shi
JDJianyi Dai
Jianyi Dai
JCJing Cai
Jing Cai
JCJing Cai
Jing Cai

30 June 2016 in SpringerPlus
Verified
Journal Article
Open access
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BCBaifeng Chen
Baifeng Chen
LLLinlin Li
Linlin Li
CDConnor Donovan
Connor Donovan
YGYongqing Gao
Yongqing Gao
GAGholam Ali
Gholam Ali
WSWenjie Sun
Wenjie Sun
Chinese citizens regularly experience some form of bodily pain, yet little is known regarding the epidemiology of pain. We conducted a nationally representative sample cross sectional study to estimate the prevalence of pain and identify risk factors of pain among 19,665 community residents aged 18–65 years in China. The China Sub-optimal Health Survey (CSHS) data was used to estimate pain prevalence. Body pain was also estimated by self-reports from the sample population. A logistical regression model was applied to estimate the odds ratio and 95 % CIs of acute pain and chronic pain to explore the potential risk factors. Women had a higher prevalence of pain than men (39.92 vs. 32.17 % for chronic pain). The prevalence of pain increased with age (29.72 % for ages 18–25 vs. 42.23 % for ages 45–65). The most common complaints were head, neck/shoulder, and waist/back pain. Females (OR 1.57, 95 % CI 1.44–1.71) ages 25 or older (25–45: OR 1.19, 95 % CI 1.04–1.36; 45–65: OR 1.47, 95 % CI 1.26–1.73) were more likely to report having chronic pain. Subjects’ living areas, and their drinking status (OR 1.32, 95 % CI 1.13–1.53) or smoking status (OR 1.01, 95 % CI 0.91–1.11), were also factors that were significantly associated with increased reporting of chronic pain. Women had a higher prevalence of chronic pain than men, although both sexes had a high prevalence for chronic pain. There were significant differences between the two sexes and the location of chronic pain in the body, most notably in the shoulders, stomach, abdomen, and waist.

2 January 2016 in Human Fertility
Verified
Journal Article
Closed access
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YZYumei Zheng
Yumei Zheng
JYJingqin Yuan
Jingqin Yuan
TXTan Xu
Tan Xu
MCMei Chen
Mei Chen
HLHui Liang
Hui Liang
YJYan Jiang
Yan Jiang
There has been a lack of socioeconomic status (SES) disparity analysis on women in China with only one child, the family planning target population. In 2008, the National Research Institute for Family Planning of China conducted a study investigating the relationship between SES and fertility intentions among 17,093 women in China who already had one child. A questionnaire was used to collect information on SES and fertility intentions, and logistic regression models were used to estimate the odds ratios and 95% CIs of fertility intentions according to SES. Compared with female farmers, women in other occupations intended to have fewer children (p < 0.05). Additionally, compared with women with low educational level (illiterate/primary), women with secondary and postsecondary education intended to have fewer children (p < 0.05) (OR = 0.70; 95% CI: 0.61–0.81 and OR = 0.56; 95% CI 0.47–0.66). A mother’s education level was significantly and negatively associated with fertility intentions after adjustment for potential confounders (p < 0.05). Among Chinese women who had one child, the women with higher SES (e.g. higher educational level) had lower fertility intentions. There is an SES disparity in the fertility intention among Chinese women who already have one child. China’s policy-makers should consider increasing high SES women’s fertility intention.