To investigate the characteristics of pesticide poisoning in Jiangsu province and provide a scientific basis for measures for the prevention of pesticide poisoning. Information from pesticide poisoning report cards from 2007 to 2016 was derived from the Occupational Disease and Occupational Health Information Monitoring System, and the characteristics of pesticide poisoning patients were assessed via descriptive analysis. A total of 30,789 pesticide poisoning cases were reported in Jiangsu Province. Of these cases, 23,557 were non-occupational poisonings, accounting for 76.5% of the reported cases. There were 1705 deaths from pesticide poisoning, and the fatality rate was 5.5%. Numerous cases occurred in northeast Jiangsu. Pesticide poisoning cases were primarily concentrated in individuals 36–60 years of age. Pesticide poisoning primarily occurred in the summer. The top types of pesticides causing poisoning were organophosphates. The fatality rate of intentional pesticide poisoning was the lowest among the age group of 0 to 14 years, while the highest was noted among people over 61 years. Therefore, pesticide poisoning is a major problem in Jiangsu Province. We need to strengthen the management of highly toxic pesticides and implement effective health education on the use of pesticides.

Background: Pesticide poisoning is an important issue in rural China, and is also a major public health problem that affects the health of farmers. The purpose of this paper is to explore the epidemiology of pesticide poisoning in Jiangsu Province, and to put forward the relevant suggestions on the logical and discerning utilization of the pesticides. Methods: According to the data of the pesticide poisoning report card established by the health hazard detection information system, the cases of pesticide poisoning in Jiangsu Province from 2006 to 2018 were exported to Excel, and the database of pesticide poisoning was established. Furthermore, the imported data was screened and collected. A descriptive statistical analysis had been employed on this data utilizing SPSS 20.0. Results: Between the years 2006 and 2018, 38,513 pesticide poisoning cases were registered in Jiangsu Province, with a downward trend. Meanwhile, 77.83% of poisoning cases involved insecticide poisoning, followed by herbicide and rodenticide. The greater part of the diverse sorts of studied insecticide poisoning cases involved people aged between 30 and 59 years (57.51%). Poisoning cases caused by rodenticide accounted for a large proportion of people aged between 0 and 14 years (23.72%) in non-occupational pesticide poisoning. Regarding seasons, it was distinguished that more insecticide cases were reported in autumn (46.95% of the total number of cases). Pesticide poisoning was reported in 13 cities of Jiangsu Province, and among these, insecticide poisoning was reported mainly from the northern Jiangsu area, which was the same as rodenticide and herbicide. Conclusions: Although there is a decreased risk for pesticide poisoning among farmworkers in Jiangsu Province, the number of farmworkers with pesticide poisoning is still high. Further management of the pesticide utilization is necessary, especially insecticide. More attention ought to be paid to the protection of vulnerable groups, including children and the elderly.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

In the article titled “Single-Nucleotide Polymorphisms in XPO5 are Associated with Noise-Induced Hearing Loss in a Chinese Population” [1], the information “Ning Wang, Boshen Wang contributed equally to this article” was omitted from the Authors’ Contributions section. The corrected section appears below:

Objectives NIHL is a disease with irreversible damage caused by multi-factor interaction, and the STAT3 is an essential protein with signal transduction and transcription functions. This study is aimed to explore the effect of STAT3 polymorphism on individual susceptibility to NIHL individuals, and to further examine the interaction between lifestyles and NIHL in the dominant model . Methods This study was designed a case-control study and included 609 NIHL cases and 611 healthy hearing controls from the Jiangsu province of China. By collecting the lifestyle and demographic information of the study participants, genotyping the collected blood samples, and performing Real-time Quantitative PCR (qRT-PCR) to analyze and investigate the potential association between STAT3 SNPs and NIHL. Results Statistical analysis results show that individuals carrying the C allele of rs1053023 and rs1053005 were more likely to develop NIHL than individuals carrying the T allele (OR = 1.367, 95% CI = 1.148–1.628, P = 0.0001 and OR = 1.37, 95% CI = 1.147–1.636, P = 0.001). In the dominant model (TC/CC genotype and TT genotype), stratified analysis of lifestyle, we found that people who smoke regularly are more likely to suffer from NIHL than non-smokers or occasional smokers. Besides, the expression of STAT3 was higher in NIHL cases by real-time quantitative PCR. Conclusion Gene polymorphisms, rs1053023 and rs1053005, from STAT3, are associated with NIHL and C alleles of rs1053023 and rs1053005 within STAT3 may become biomarkers for workers exposed to noise.