Encompassing all fields of chemical research, BMC Chemistry is an open access, peer reviewed journal that publishes articles on fundamental concepts, new developments and the application of chemical principles to a broad range of research fields, industry, and other disciplines. The journal provides an inclusive platform for the dissemination and discussion of chemistry to aid the advancement of all areas of research. Supported by a highly experienced global Editorial Board, this journal is part of the BMC series, a collection of journals that are focused on individual research communities, publishing all scientifically valid studies based on community-aligned standards of questioning, methods and analysis.

Various kinds of materials are used for wound healing. But natural polymers are more effective in wound healing as compare to synthetic polymers. Chitosan being a natural biopolymer exhibit various biological properties like biocompatibility, biodegradability, and many other good properties which makes it convenient to use for wound healing application. Different types of chitosan based hybrid materials are used to prepare wound healing nanocomposites, hydrogel sheets, membranes, films, sponges and other hybrid composites using various techniques. This review highlighted the formulation and biological evaluation of various chitosan based hybrid materials as wound dressing.

Tetraphenylethylene (TPE) can be used to construct fluorescent probes with typical aggregation-induced emission (AIE) behavior for next-generation sensing applications. McMurry coupling and Suzuki cross coupling strategies provided the desired sensor thiophene-substituted tetraphenylethylene (THTPE). The synthesized TPE analogues were characterized by NMR spectroscopy and mass spectrometry. Maximum AIE of THTPE was observed in 90% water (H₂O/THF) content due to extensive formation of aggregates. The AIE properties of THTPE have been utilized for facile detection of nitroaromatic compounds (NACs) (1.0 nM) through a fluorescence quenching mechanism. A paper strip adsorbed with the AIE-based THTPE fluorophore is developed for rapid and convenient detection of NAC-based analytes. Further, interaction of THTPE with analytes is also studied via Gaussian software at the DFT/B3LYP/6-31G(d) level of theory. Interaction energy, frontier molecular orbitals (FMOs), and non-covalent interaction (NCI) analyses are studied by using the same method. Computational results revealed that nitrobenzene (NB) has the strongest interaction while 1,3-dinitrobenzene (DNB) exhibits the least interaction with the sensor molecule. These computational results clearly demonstrate good agreement with experimental data.