MÜGE GÜLEN

Dr. MÜGE GÜLEN

orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 September 2020 in Clinics and Research in Hepatology and Gastroenterology
Verified
Journal Article
Closed access
MGMÜGE GÜLEN
MÜGE GÜLEN
SSSalim Satar
Salim Satar

1 November 2020 in Alcohol
Verified
Journal Article
Closed access
MGMÜGE GÜLEN
MÜGE GÜLEN
SSSalim Satar
Salim Satar
AAAkkan Avci
Akkan Avci
SASelen Acehan
Selen Acehan
UOUgur Orhan
Ugur Orhan
HNHakan Nazik
Hakan Nazik

20 September 2022 in Scandinavian Journal of Clinical and Laboratory Investigation
Verified
Journal Article
Closed access
SSSarper Sevdımbas
Sarper Sevdımbas
SSSalim Satar
Salim Satar
MGMÜGE GÜLEN
MÜGE GÜLEN
SASelen Acehan
Selen Acehan
AAArmagan Acele
Armagan Acele
DSDeniz Aka Satar
Deniz Aka Satar
The aim of this study is to reveal the predictive power of biomarkers and SYNTAX (SX) score for short-term mortality in patients diagnosed with non-ST-segment elevation myocardial infarction (NSTEMI) in the emergency department. This is prospective observational cohort study. Demographic characteristics of the patients, laboratory parameters on admission, left ventricular ejection fraction (LVEF) percentages, affected vessels in angiography (CAG) and the treatment strategy [medical therapy, percutaneous transluminal coronary angioplasty (PTCA), coronary angio by-pass graft] and SX scores were recorded on the data collection form. ROC curve was used to investigate the predictivity of blood urea nitrogen/albumin ratio (BAR), procalcitonin, C-reactive protein (CRP), high sensitivity cardiac troponin I (Hs-cTnI), CRP to serum albumin ratio (CAR), neutrophil to lymphocyte ratio (NLR) and SX scores in mortality. Multivariate analysis of biomarkers and SX score was performed to estimate the patients’ 30-day mortality. Of the 415 patients were included in the study. ROC analysis of BAR, CAR, CRP, Procalcitonin, Hs-cTnI, NLR and SX score to predict mortality was statistically significant. BAR (OR: 1.280, 95% CI: 1.113–1.472, p = .001) and SX score (OR: 1.071, 95% CI: 1.018–1.126, p = .007) were found to be independent predictors of 30 days mortality. LVEF reduction, SX score, the number of affected vessels and the frequency of LMCA lesions increase were found to be statistically significant in patients with BAR ≥4.8. BAR, which can be calculated easily and quickly on admission to the emergency department and in clinical practice, may be used to predict mortality in patients with NSTEMI.

24 October 2019 in Gastroenterology Research and Practice
Verified
Journal Article
Open access
PDF file
MGMÜGE GÜLEN
MÜGE GÜLEN
SSSalim Satar
Salim Satar
ATAdnan Tas
Adnan Tas
AAAkkan Avci
Akkan Avci
HNHakan Nazik
Hakan Nazik
BFBasak Toptas Firat
Basak Toptas Firat
Background and Objectives. The aim of this study was to show whether the level of lactate in venous blood compared with the Glasgow-Blatchford Bleeding Score (GBS), in patients diagnosed with upper gastrointestinal system (UGI) bleeding in the emergency department, will help to predict the need for transfusion and prognosis.Materials and Methods. Patients with UGI bleeding who were admitted to the emergency department were included in the study. The parameters age, gender, referral complaints, comorbidities, lactate levels in venous blood, GBS, endoscopy findings, length of hospital stay, transfusion amount, and outcome of patients were recorded in the data collection form.Results. A total of 139 patients were included in the study. The most common complaints were melena (38.1%) and hematemesis (32.4%). The most frequent endoscopic diagnosis was duodenal ulcer (40.3%). The cutoff value of the venous blood lactate level for the prediction of the need for red blood cell transfusion was 1.58 mmol/L, and the cutoff value for GBS was 9.5. While 124 patients were discharged, 15 patients died. The mean value of venous lactate in survived patients was 2.37 mmol/L and 4.80 in dead patients. This difference was statistically significant (p=0.044). The cutoff value of lactate for the prediction of mortality was 2.32 mmol/L, and the cutoff value for GBS was 13.5.Conclusions. The venous blood lactate value of a patient who was admitted to the emergency department with UGI bleeding might be helpful in predicting the transfusion needs of the patient and predicting the mortality.

1 January 2021 in The American Journal of Emergency Medicine
Verified
Journal Article
Closed access
SASelen Acehan
Selen Acehan
SSSalim Satar
Salim Satar
MGMÜGE GÜLEN
MÜGE GÜLEN
AAAkkan Avci
Akkan Avci

9 March 2020 in Emergency Medicine International
Verified
Journal Article
Open access
PDF file
BABegüm Şeyda Avci
Begüm Şeyda Avci
AAAkkan Avci
Akkan Avci
YDYurdaer Dönmez
Yurdaer Dönmez
AKAdem Kaya
Adem Kaya
MGMÜGE GÜLEN
MÜGE GÜLEN
SSSalim Satar
Salim Satar
Background. Myocardial infarction is the most common cause of death all over the world. There are many studies in predicting mortality. The aim of this study was to determine the effectiveness of hematologic parameters measured at the moment of admission to the emergency room in predicting in-hospital mortality and to determine cutoff values of strongly predictive values. Methods. A total of 681 patients over 18 years of age, whose date could be obtained, were included in the study. From the hemogram parameters, white blood cells (WBC), red cell distribution width (RDW), mean platelet volume (MPV), and neutrophils-to-lymphocytes ratio (NLR) values were determined and recorded. CK-MB and high-sensitive troponin T values were recorded as cardiac markers. For statistical analysis, “SPSS for Windows version 21” package program was used. Results. 62.6% (n = 426) of the patients were male, and 37.4% (n = 255) of the patients were female. The NLR was found to be the strongest predictor (area under the curve (AUC), 0.783, SD = 0.052, 95% confidence interval (CI)). It was found that the WBC value came in the second place after NLR as a strong predictor of mortality (AUC, 0.702, SD = 0.075, 95% CI). Conclusion. According to the hemogram results which were acquired with a simple and cheap method, we found that WBC and especially NLR values obtained with a simple method can be used as powerful predictors.