Gyula Palyi

Prof. Gyula Palyi

Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, I-41125 Modena, Italy

Research Focus & Metrics

Academic Career Length

36Years (1991-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
28 April 2010 in Journal of Mathematical Chemistry
Verified
Journal Article
Closed access
PDF file
BBBéla Barabás
Béla Barabás
JTJanos Toth
Janos Toth
Gyula PalyiGyula Palyi
Gyula Palyi

16 June 2010 in Chemistry & Biodiversity
Verified
Journal Article
Closed access
PDF file
KMKároly Micskei
Károly Micskei
TPTamás Patonay
Tamás Patonay
LCLuciano Caglioti
Luciano Caglioti
Gyula PalyiGyula Palyi
Gyula Palyi

3 February 2015 in Journal of Molecular Modeling
Verified
Journal Article
Open access
PDF file
BBBéla Barabás
Béla Barabás
CZClaudia Zucchi
Claudia Zucchi
MMMarco Maioli
Marco Maioli
KMKároly Micskei
Károly Micskei
Gyula PalyiGyula Palyi
Gyula Palyi
Absolute asymmetric synthesis (AAS) is the preparation of pure (or excess of one) enantiomer of a chiral compound from achiral precursor(s) by a chemical reaction, without enantiopure chiral additive and/or without applied asymmetric physical field. Only one well-characterized example of AAS is known today: the Soai-autocatalysis. In an attempt at clarification of the mechanism of this particular reaction we have undertaken empirical and stochastic analysis of several parallel AAS experiments. Our results show that the initial steps of the reaction might be controlled by simple normal distribution (“coin tossing”) formalism. Advanced stages of the reaction, however, appear to be of a more complicated nature. Symmetric beta distribution formalism could not be brought into correspondence with the experimental observations. A bimodal beta distribution algorithm provided suitable agreement with the experimental data. The parameters of this bimodal beta function were determined by a Pólya-urn experiment (simulated by computer). Interestingly, parameters of the resulting bimodal beta function give a golden section ratio. These results show, that in this highly interesting autocatalysis two or even perhaps three catalytic cycles are cooperating. An attempt at constructing a “designed” Soai-type reaction system has also been made.

8 January 2016 in Symmetry
Verified
Journal Article
Open access
PDF file
BBBéla Barabás
Béla Barabás
RKRobert Kurdi
Robert Kurdi
Gyula PalyiGyula Palyi
Gyula Palyi
Isotopic chirality influences sensitively the enantiomeric outcome of the Soai asymmetric autocatalysis. Therefore magnitude and eventual effects of isotopic chirality caused by natural abundance isotopic substitution (H, C, O, Zn) in the reagents of the Soai reaction were analyzed by combinatorics and probability calculations. Expectable enantiomeric excesses were calculated by the Pars–Mills equation. It has been found that the chiral isotopic species formed by substitution in the otherwise achiral reagents provide enantiomeric excess (e.e.) levels that are higher than the sensitivity threshold of the Soai autocatalysis towards chiral induction. Consequently, possible chiral induction exerted by these e.e. values should be taken into account in considerations regarding the molecular events and the mechanism of the chiral induction in the Soai reaction.

20 July 2016 in The Journal of Physical Chemistry B
Verified
Journal Article
Closed access
MMMarco Maioli
Marco Maioli
GVGyula Varadi
Gyula Varadi
RKRóbert Kurdi
Róbert Kurdi
LCLuciano Caglioti
Luciano Caglioti
Gyula PalyiGyula Palyi
Gyula Palyi

7 May 2018 in Chirality
Verified
Journal Article
Closed access
PDF file
BBBéla Barabás
Béla Barabás
RKRobert Kurdi
Robert Kurdi
CZClaudia Zucchi
Claudia Zucchi
Gyula PalyiGyula Palyi
Gyula Palyi