'%3e%3cpath%20d='M22.1642%2019.0924C21.7317%2018.068%2021.1041%2017.1375%2020.3163%2016.3527C19.5309%2015.5656%2018.6006%2014.9381%2017.5766%2014.5048C17.5674%2014.5002%2017.5582%2014.4979%2017.5491%2014.4933C18.9774%2013.4616%2019.9059%2011.7811%2019.9059%209.88504C19.9059%206.74408%2017.3611%204.19922%2014.2201%204.19922C11.0792%204.19922%208.53429%206.74408%208.53429%209.88504C8.53429%2011.7811%209.46282%2013.4616%2010.8912%2014.4956C10.882%2014.5002%2010.8728%2014.5025%2010.8636%2014.5071C9.83652%2014.9404%208.91487%2015.5617%208.1239%2016.355C7.33685%2017.1404%206.70933%2018.0707%206.276%2019.0947C5.85031%2020.0972%205.62072%2021.172%205.59967%2022.2609C5.59905%2022.2853%205.60335%2022.3097%205.61229%2022.3325C5.62123%2022.3553%205.63465%2022.376%205.65174%2022.3935C5.66883%2022.4111%205.68926%2022.425%205.71182%2022.4345C5.73437%2022.444%205.7586%2022.4489%205.78308%2022.4489H7.15868C7.25956%2022.4489%207.3398%2022.3686%207.3421%2022.2701C7.38795%2020.5001%208.09868%2018.8425%209.35506%2017.5861C10.655%2016.2862%2012.3814%2015.5709%2014.2201%2015.5709C16.0588%2015.5709%2017.7852%2016.2862%2019.0852%2017.5861C20.3415%2018.8425%2021.0523%2020.5001%2021.0981%2022.2701C21.1004%2022.3709%2021.1807%2022.4489%2021.2815%2022.4489H22.6571C22.6816%2022.4489%2022.7058%2022.444%2022.7284%2022.4345C22.751%2022.425%2022.7714%2022.4111%2022.7885%2022.3935C22.8056%2022.376%2022.819%2022.3553%2022.8279%2022.3325C22.8369%2022.3097%2022.8412%2022.2853%2022.8406%2022.2609C22.8176%2021.165%2022.5907%2020.0989%2022.1642%2019.0924ZM14.2201%2013.8284C13.1678%2013.8284%2012.1773%2013.418%2011.4322%2012.6729C10.6871%2011.9278%2010.2767%2010.9374%2010.2767%209.88504C10.2767%208.83271%2010.6871%207.84227%2011.4322%207.09715C12.1773%206.35204%2013.1678%205.94165%2014.2201%205.94165C15.2724%205.94165%2016.2629%206.35204%2017.008%207.09715C17.7531%207.84227%2018.1635%208.83271%2018.1635%209.88504C18.1635%2010.9374%2017.7531%2011.9278%2017.008%2012.6729C16.2629%2013.418%2015.2724%2013.8284%2014.2201%2013.8284Z'%20fill='%238590A2'/%3e%3c/g%3e%3c/svg%3e)
Research Focus & Metrics
Explore full metrics on Scilit
Academic Career Length
29Years (1998-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 May 2018 in Advanced Drug Delivery Reviews
Journal Article
SGSusanne K. Golombek
Susanne K. Golombek
JMJan-Niklas May
Jan-Niklas May
BTBenjamin Theek
Benjamin Theek
LALia Appold
Lia Appold
NDNatascha Drude
Natascha Drude
Twan Lammers +1
6 November 2019 in Nature Nanotechnology
Journal Article
RMRoy van der Meel
Roy van der MeelESEinar Sulheim
Einar Sulheim
YSYang Shi
Yang Shi
Fabian KiesslingWMWillem J. M. Mulder
Willem J. M. Mulder
Twan Lammers1 January 2019 in Advanced Drug Delivery Reviews
Journal Article
SDSeyed Mohammadali Dadfar
Seyed Mohammadali DadfarKRKarolin Roemhild
Karolin Roemhild
NDNatascha Drude
Natascha DrudeSSSaskia von Stillfried
Saskia von StillfriedRKRuth Knüchel
Ruth Knüchel
Twan Lammers +1
5 May 2011 in Accounts of Chemical Research
Journal Article
Twan LammersSASilvio Aime
Silvio AimeWHWim E. Hennink
Wim E. Hennink
GSGert Storm
Gert Storm
Fabian Kiessling2 March 2014 in Nature Medicine
Journal Article
ASAndreas Schober
Andreas SchoberMNMaliheh Nazari-Jahantigh
Maliheh Nazari-Jahantigh
YWYuanyuan Wei
Yuanyuan Wei
KBKiril Bidzhekov
Kiril Bidzhekov
FGFelix Gremse
Felix Gremse
CWChristian Weber
Christian Weber +8
2 November 2018 in Frontiers in Pharmacology
Journal Article
SRSima Rezvantalab
Sima Rezvantalab
NDNatascha Drude
Natascha DrudeMMMostafa Keshavarz moraveji
Mostafa Keshavarz moravejiNGNihan Güvener
Nihan GüvenerEKEmily Kate Koons
Emily Kate Koons
Fabian Kiessling +2
Nanomedicines can be used for a variety of cancer therapies including tumor-targeted drug delivery, hyperthermia, and photodynamic therapy. Poly (lactic-co-glycolic acid) (PLGA)-based materials are frequently used in such setups. This review article gives an overview of the properties of previously reported PLGA nanoparticles (NPs), their behavior in biological systems, and their use for cancer therapy. Strategies are emphasized to target PLGA NPs to the tumor site passively and actively. Furthermore, combination therapies are introduced that enhance the accumulation of NPs and, thereby, their therapeutic efficacy. In this context, the huge number of reports on PLGA NPs used as drug delivery systems in cancer treatment highlight the potential of PLGA NPs as drug carriers for cancer therapeutics and encourage further translational research.
About Me
Prof. Dr. Fabian Kiessling is Full Professor at the Department of Experimental Molecular Imaging, RWTH Aachen University. He studied Medicine at the University in Heidelberg, and has authored over 400 publications and book chapters, edited four books, and received multiple research awards and honours, including the “Emil Salzer Prize for Cancer Research” and the “Richtzenhain Prize”. Professor Kiessling has served in the Editorial board of several scientific journals including Radiology, European Radiology, J Nuclear Medicine, and Molecular Imaging and Biology. In addition, in 2014 he chaired the “Molecular Imaging” subcommittee of the European Society for Radiology (ESR) and was appointed as program chair of the World Molecular Imaging Conference (WMIS) in New York in 2016. In 2020 he was awarded by the World Molecular Imaging Society as Fellow. His interests include magnetic resonance imaging, magnetic particle imaging, Ultrasound, optical imaging/optical tomography, positron emission tomography.