Lipid metabolism may be involved in the pathogenic mechanism of age-related macular degeneration (AMD). However, conflicting results have been reported in the associations of AMD with blood lipids. We performed a meta-analysis including a total of 19 studies to evaluate associations between blood lipids and this disease. The result reported that the high level of high-density lipoprotein cholesterol (HDL-C) obtained with an increment of 1 mmol/L could result in a significantly increase in the AMD risk of approximately 18% (relative risk (RR), 1.18; 95% confidence interval (CI), 1.01 to 1.35; I² = 53.8%; p = 0.007). High levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) were significantly associated with a decreased risk of AMD (RRs ranging from 0.92 to 0.95; all p < 0.05). The stratified analysis based on AMD subtypes showed that these blood lipids were only significantly associated with the risk of early AMD (all p < 0.05). The association between the blood lipids and AMD risk did not differ substantially based on the other characteristics of the participants. A high HDL-C level was associated with an increased AMD risk, whereas participants with high TC, LDL-C, and TG concentrations may show a decreased risk for this disease. Further well-designed large studies are warranted to confirm the conclusions.

With the development of unmanned aerial vehicle (UAV) and artificial intelligence (AI) technology, Intelligent UAV will be widely used in future autonomous aerial combat. Previous researches on autonomous aerial combat within visual range (WVR) have limitations due to simplifying assumptions, limited robustness, and ignoring sensor errors. In this paper, in order to consider the error of the aircraft sensors, we model the aerial combat WVR as a state-adversarial Markov decision process (SA-MDP), which introduce the small adversarial perturbations on state observations and these perturbations do not alter the environment directly, but can mislead the agent into making suboptimal decisions. Meanwhile, we propose a novel autonomous aerial combat maneuver strategy generation algorithm with high-performance and high-robustness based on state-adversarial deep deterministic policy gradient algorithm (SA-DDPG), which add a robustness regularizers related to an upper bound on performance loss at the actor-network. At the same time, a reward shaping method based on maximum entropy (MaxEnt) inverse reinforcement learning algorithm (IRL) is proposed to improve the aerial combat strategy generation algorithm’s efficiency. Finally, the efficiency of the aerial combat strategy generation algorithm and the performance and robustness of the resulting aerial combat strategy is verified by simulation experiments. Our main contributions are three-fold. First, to introduce the observation errors of UAV, we are modeling air combat as SA-MDP. Second, to make the strategy network of air combat maneuver more robust in the presence of observation errors, we introduce regularizers into the policy gradient. Third, to solve the problem that air combat’s reward function is too sparse, we use MaxEnt IRL to design a shaping reward to accelerate the convergence of SA-DDPG.

In real applications, how to measure the uncertain degree of sensor reports before applying sensor data fusion is a big challenge. In this paper, in the frame of Dempster–Shafer evidence theory, a weighted belief entropy based on Deng entropy is proposed to quantify the uncertainty of uncertain information. The weight of the proposed belief entropy is based on the relative scale of a proposition with regard to the frame of discernment (FOD). Compared with some other uncertainty measures in Dempster–Shafer framework, the new measure focuses on the uncertain information represented by not only the mass function, but also the scale of the FOD, which means less information loss in information processing. After that, a new multi-sensor data fusion approach based on the weighted belief entropy is proposed. The rationality and superiority of the new multi-sensor data fusion method is verified according to an experiment on artificial data and an application on fault diagnosis of a motor rotor.

Efficient data processing and computation are essential for the Industrial Internet of Things (IIoT) to empower various applications, which can be significantly bottlenecked by the limited energy capacity and computation capability of the IIoT nodes. In this article, we employ an unmanned aerial vehicle (UAV) as an edge server to assist IIoT data processing, while considering the practical issue of UAV jittering. Specifically, we propose a joint design on trajectory and offloading strategies to minimize energy consumption due to local and edge computation, as well as data transmission. We particularly address UAV jittering that induces Gaussian-distributed uncertainties associated with flying waypoints, resulting in probabilistic-form flying speed and data offloading constraints. We exploit the Bernstein-type inequality to reformulate the constraints in deterministic forms and decompose the energy minimization to solve for trajectory and offloading separately within an alternating optimization framework. The subproblems are then tackled with the successive convex approximation technique. Simulation results show that our proposal strictly guarantees robustness under uncertainties and effectively reduces energy consumption as compared with the baselines.

Distributed multi-agent collaborative decision-making technology is the key to general artificial intelligence. This paper takes the self-developed Unity3D collaborative combat environment as the test scenario, setting a task that requires heterogeneous unmanned aerial vehicles (UAVs) to perform a distributed decision-making and complete cooperation task. Aiming at the problem of the traditional proximal policy optimization (PPO) algorithm’s poor performance in the field of complex multi-agent collaboration scenarios based on the distributed training framework Ray, the Critic network in the PPO algorithm is improved to learn a centralized value function, and the muti-agent proximal policy optimization (MAPPO) algorithm is proposed. At the same time, the inheritance training method based on course learning is adopted to improve the generalization performance of the algorithm. In the experiment, MAPPO can obtain the highest average accumulate reward compared with other algorithms and can complete the task goal with the fewest steps after convergence, which fully demonstrates that the MAPPO algorithm outperforms the state-of-the-art.

This study deals with the autonomous evasive maneuver strategy of unmanned combat air vehicle (UCAV), which is threatened by a high-performance beyond-visual-range (BVR) air-to-air missile (AAM). Considering tactical demands of achieving self-conflicting evasive objectives in actual air combat, including higher miss distance, less energy consumption and longer guidance support time, the evasive maneuver problem in BVR air combat is defined and reformulated into a multi-objective optimization problem. Effective maneuvers of UCAV used in different evasion phases are modeled in three-dimensional space. Then the three-level decision space structure is established according to qualitative evasive tactical planning. A hierarchical multi-objective evolutionary algorithm (HMOEA) is designed to find the approximate Pareto-optimal solutions of the problem. The approach combines qualitative tactical experience and quantitative maneuver decision optimization method effectively. Simulations are used to demonstrate the feasibility and effectiveness of the approach. The results show that the obtained set of decision variables constitutes nondominated solutions, which can meet different evasive tactical requirements of UCAV while ensuring successful evasion.