• Machine Learning in drug discovery has greatly benefited the pharmaceutical industry. • Application of machine algorithms must entail a robust design in real clinical tasks. • Trending machine learning algorithms in drug design: NB, SVM, RF and ANN.

Automatic prediction of the aesthetic value of images has received increasing attention in recent years. This is due, on the one hand, to the potential impact that predicting the aesthetic value has on practical applications. Even so, it remains a difficult task given the subjectivity and complexity of the problem. An image aesthetics assessment system was developed in recent years by our research group. In this work, its potential to be applied in commercial tasks is tested. With this objective, a set of three portals and three real estate agencies in Spain were taken as case studies. Images of their websites were taken to build the experimental dataset and a validation method was developed to test their original order with another proposed one according to their aesthetic value. So, in this new order, the images that have the high aesthetic score by the AI system will occupy the first positions of the portal. Relevant results were obtained, with an average increase of 52.54% in the number of clicks on the ads, in the experiment with Real Estate portals. A statistical analysis prove that there is a significant difference in the number of clicks after selecting the images with the AI system.

An important topic in evolutionary art is the development of systems that can mimic the aesthetics decisions made by human begins, e.g., fitness evaluations made by humans using interactive evolution in generative art. This paper focuses on the analysis of several datasets used for aesthetic prediction based on ratings from photography websites and psychological experiments. Since these datasets present problems, we proposed a new dataset that is a subset of DPChallenge.com. Subsequently, three different evaluation methods were considered, one derived from the ratings available at DPChallenge.com and two obtained under experimental conditions related to the aesthetics and quality of images. We observed different criteria in the DPChallenge.com ratings, which had more to do with the photographic quality than with the aesthetic value. Finally, we explored learning systems other than state‐of‐the‐art ones, in order to predict these three values. The obtained results were similar to those using state‐of‐the‐art procedures.

Providing the visual complexity of an image in terms of impact or aesthetic preference can be of great applicability in areas such as psychology or marketing. To this end, certain areas such as Computer Vision have focused on identifying features and computational models that allow for satisfactory results. This paper studies the application of recent ML models using input images evaluated by humans and characterized by features related to visual complexity. According to the experiments carried out, it was confirmed that one of these methods, Correlation by Genetic Search (CGS), based on the search for minimum sets of features that maximize the correlation of the model with respect to the input data, predicted human ratings of image visual complexity better than any other model referenced to date in terms of correlation, RMSE or minimum number of features required by the model. In addition, the variability of these terms were studied eliminating images considered as outliers in previous studies, observing the robustness of the method when selecting the most important variables to make the prediction.

Image Enhancement (IE) is an image processing procedure in which the image’s original information is improved, highlighting specific features to ease post-processing analyses by a human or machine. State-of-the-art image enhancement pipelines apply solutions to fixed and static constraints to solve specific issues in isolation. In this work, an IE system for image marketing is proposed, more precisely, real estate marketing, where the objective is to enhance the commercial appeal of the images, while maintaining a level of realism and similarity with the original image. This work proposes a generic image enhancement pipeline that combines state-of-the-art image processing filters, Machine Learning methods, and Evolutionary approaches, such as Genetic Programming (GP), to create a dynamic framework for Image Enhancement. The GP-based system is trained to optimize 4 metrics: Neural Image Assessment (NIMA) technical and BRISQUE, which evaluate the technical quality of the images; and NIMA aesthetics and PhotoILike, that evaluate the commercial attractiveness. It is shown that the GP model was able to find the best image quality enhancement (0.97 NIMA Aesthetics), while maintaining a high level of similarity with the original images (Structural Similarity Index Measure (SSIM) of $0.88$). The framework has better performance according to the image quality metrics than the off-the-shelf image enhancement tool and the framework’s isolated parts.