Uma Shankar Gautam

Dr. Uma Shankar Gautam

Duke Human Vaccine Institute, Duke University, Durham, California, USA
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Biography

I have broad research interests in the areas of infectious diseases, microbiology, immunology, inflammation, host-directed immunotherapy, and tuberculosis drugs. I am currently investigating the role of memory B cells in TB using a cutting-edge single-cell flow cytometry approach with the main aim to isolate antibodies and develop an mRNA-based vaccine for TB. I use ex-vivo co-culture (macrophages and T-cells) and small animal models to determine the cellular and molecular mechanisms of TB pathogenesis. Another area of my research interest is phosphoproteomics of lung cells with intracellular mycobacteria to understand modulation in the host niche during TB disease progression.

Affiliations

Duke University

Durham, California, USA

Duke Human Vaccine Institute

Honors and Awards

honor

Early Career Scientist Award from

Bill and Melinda Gates Foundation.

My contribution to TB field.

honor

Travel award

Tulane University.

Travel award from Office of Graduate and Postdoctoral Studies, Tulane University.

honor

Senior Research Associateship

Council of Scientific and Industrial Research, India.

Scientific Pool Officer Senior Research Associateship from Council of Scientific and Industrial Research, India.

Experience

Senior Scientist or Principal Investigator

Duke Human vaccine Institute

01 Jan 2019 - present