Brenda Golianu

Dr. Brenda Golianu

Department of Anesthesiology Perioperative Medicine and Pain Management, Stanford University School of Medicine, Palo Alto, CA 94304, USA
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Research Focus & Metrics

Academic Career Length

22Years (2005-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 June 2017 in Children
Verified
Journal Article
Open access
PDF file
AWAndrea Won
Andrea Won
JBJakki Bailey
Jakki Bailey
JBJeremy Bailenson
Jeremy Bailenson
CTChristine Tataru
Christine Tataru
IYIsabel A. Yoon
Isabel A. Yoon
BGBrenda Golianu
Brenda Golianu
Children must often endure painful procedures as part of their treatment for various medical conditions. Those with chronic pain endure frequent or constant discomfort in their daily lives, sometimes severely limiting their physical capacities. With the advent of affordable consumer-grade equipment, clinicians have access to a promising and engaging intervention for pediatric pain, both acute and chronic. In addition to providing relief from acute and procedural pain, virtual reality (VR) may also help to provide a corrective psychological and physiological environment to facilitate rehabilitation for pediatric patients suffering from chronic pain. The special qualities of VR such as presence, interactivity, customization, social interaction, and embodiment allow it to be accepted by children and adolescents and incorporated successfully into their existing medical therapies. However, the powerful and transformative nature of many VR experiences may also pose some risks and should be utilized with caution. In this paper, we review recent literature in pediatric virtual reality for procedural pain and anxiety, acute and chronic pain, and some rehabilitation applications. We also discuss the practical considerations of using VR in pediatric care, and offer specific suggestions and information for clinicians wishing to adopt these engaging therapies into their daily clinical practice.

1 February 2005 in Current Opinion in Anaesthesiology
Verified
Journal Article
Closed access
BGBrenda Golianu
Brenda Golianu
GHGregory B Hammer
Gregory B Hammer
Purpose of review Surgical interventions, including video-assisted thoracoscopic surgeries, are increasingly being performed in the neonatal and pediatric populations. Thoracic anesthesia in infants and children poses special challenges for the anesthesiologist. These include assessment of the patient's clinical condition, obtaining and maintaining single lung ventilation, and maintaining adequate ventilation and oxygenation while the surgery is in progress. Recent findings This review will outline the anesthetic management of infants and children undergoing thoracic surgery, including preoperative assessment, and anesthetic induction and maintenance. The physiology and methods of single lung ventilation will be reviewed, including the use of bronchial blockers, Univent tubes and double-lumen tubes. Special considerations for video-assisted thoracoscopic surgery, pectus repair and mediastinal masses will be discussed. Summary These techniques will provide the anesthesiologist with a number of strategies for assessing the pediatric thoracic patient and for managing pediatric single lung ventilation. Abbreviations DLT: double lumen tube; ETT: endotracheal tube; SLV: single lung ventilation; V/Q: ventilation/perfusion.

1 October 2007 in Seminars in Perinatology
Verified
Journal Article
Closed access
BGBrenda Golianu
Brenda Golianu
EKElliot Krane
Elliot Krane
JSJeannie Seybold
Jeannie Seybold
CAChris Almgren
Chris Almgren
KAKanwaljeet J. S. Anand
Kanwaljeet J. S. Anand

21 February 2019 in Children
Verified
Journal Article
Open access
PDF file
AWAna Vanessa Wren
Ana Vanessa Wren
ARAlexandra C. Ross
Alexandra C. Ross
GDGenevieve D’Souza
Genevieve D’Souza
CAChristina Almgren
Christina Almgren
AFAmanda Feinstein
Amanda Feinstein
BGBrenda Golianu
Brenda Golianu
Opioid therapy is the cornerstone of treatment for acute procedural and postoperative pain and is regularly prescribed for severe and debilitating chronic pain conditions. Although beneficial for many patients, opioid therapy may have side effects, limited efficacy, and potential negative outcomes. Multidisciplinary pain management treatments incorporating pharmacological and integrative non-pharmacological therapies have been shown to be effective in acute and chronic pain management for pediatric populations. A multidisciplinary approach can also benefit psychological functioning and quality of life, and may have the potential to reduce reliance on opioids. The aims of this paper are to: (1) provide a brief overview of a multidisciplinary pain management approach for pediatric patients with acute and chronic pain, (2) highlight the mechanisms of action and evidence base of commonly utilized integrative non-pharmacological therapies in pediatric multidisciplinary pain management, and (3) explore the opioid sparing effects of multidisciplinary treatment for pediatric pain.

23 November 2020 in JMIR Rehabilitation and Assistive Technologies
Verified
Journal Article
Open access
AGAnya Griffin
Anya Griffin
LWLuke Wilson
Luke Wilson
AFAmanda Feinstein
Amanda Feinstein
ABAdeline Bortz
Adeline Bortz
MHMarissa S Heirich
Marissa S Heirich
Laura SimonsLaura Simons
Laura Simons
Background: In the field of pain, virtual reality (VR) technology has been increasingly common in the context of procedural pain management. As an interactive technology tool, VR has the potential to be extended beyond acute pain management to chronic pain rehabilitation with a focus on increasing engagement with painful or avoided movements. Objective: We outline the development and initial implementation of a VR program in pain rehabilitation intervention to enhance function in youth with chronic pain. Methods: We present the development, acceptability, feasibility, and utility of an innovative VR program (Fruity Feet) for pediatric pain rehabilitation to facilitate increased upper and lower extremity engagement. The development team was an interdisciplinary group of pediatric experts, including physical therapists, occupational therapists, pain psychologists, anesthesiologists, pain researchers, and a VR software developer. We used a 4-phase iterative development process that engaged clinicians, parents, and patients via interviews and standardized questionnaires. Results: This study included 17 pediatric patients (13 female, 4 male) enrolled in an intensive interdisciplinary pain treatment (IIPT) program, with mean age of 13.24 (range 7-17) years, completing a total of 63 VR sessions. Overall reports of presence were high (mean 28.98; max 40; SD 4.02), suggestive of a high level of immersion. Among those with multisession data (n=8), reports of pain (P<.001), fear (P=.003), avoidance (P=.004), and functional limitations (P=.01) significantly decreased. Qualitative analysis revealed (1) a positive experience with VR (eg, enjoyed VR, would like to utilize the VR program again, felt VR was a helpful tool); (2) feeling distracted from pain while engaged in VR; (3) greater perceived mobility; and (4) fewer clinician-observed pain behaviors during VR. Movement data support the targeted impact of the Fruity Feet compared to other available VR programs. Conclusions: The iterative development process yielded a highly engaging and feasible VR program based on qualitative feedback, questionnaires, and movement data. We discuss next steps for the refinement, implementation, and assessment of impact of VR on chronic pain rehabilitation. VR holds great promise as a tool to facilitate therapeutic gains in chronic pain rehabilitation in a manner that is highly reinforcing and fun.

26 April 2017 in Children
Verified
Journal Article
Open access
PDF file
LWLynn Waelde
Lynn Waelde
AFAmanda Feinstein
Amanda Feinstein
RBRashmi Bhandari
Rashmi Bhandari
AGAnya Griffin
Anya Griffin
IYIsabel A. Yoon
Isabel A. Yoon
BGBrenda Golianu
Brenda Golianu
Despite advances in psychological interventions for pediatric chronic pain, there has been little research examining mindfulness meditation for these conditions. This study presents data from a pilot clinical trial of a six-week manualized mindfulness meditation intervention offered to 20 adolescents aged 13–17 years. Measures of pain intensity, functional disability, depression and parent worry about their child’s pain were obtained at baseline and post-treatment. Results indicated no significant changes in pain or depression, however functional disability and frequency of pain functioning complaints improved with small effect sizes. Parents’ worry about child’s pain significantly decreased with a large effect size. Participants rated intervention components positively and most teens suggested that the number of sessions be increased. Three case examples illustrate mindfulness meditation effects and precautions. Mindfulness meditation shows promise as a feasible and acceptable intervention for youth with chronic pain. Future research should optimize intervention components and determine treatment efficacy.