My research focuses on two main areas. The first involves investigating host defense mechanisms against microscopic fungi, with an emphasis on mast cell response to fungi-derived molecules, the engagement of pattern recognition receptors, and the molecular pathways involved in pathogen recognition. These studies aim to advance the understanding of host-pathogenic fungi interactions. The second area of research concerns the role of adipokines—bioactive molecules secreted by adipose tissue—in regulating mast cell activity. The second area of research concerns how adipokines, bioactive molecules primarily secreted by adipose tissue, impact mast cell functions, particularly in relation to low-grade inflammation. The goal is to elucidate the cross-talk between metabolic and immune systems and to identify potential points of therapeutic intervention.