Andreas Holtermann

Prof. Andreas Holtermann

The National Research Centre for the Working Environment, 2100 Copenhagen, Denmark
+1
orcid

Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 April 2011 in British Journal of Sports Medicine
Verified
Journal Article
Closed access
PDF file
AHAndreas Holtermann
Andreas Holtermann
JHJ V Hansen
J V Hansen
HBH Burr
H Burr
Karen SøgaardKaren Søgaard
Karen Søgaard
GSGisela Sjøgaard
Gisela Sjøgaard
Background Occupational and leisure-time physical activity are considered to provide similar health benefits. The authors tested this hypothesis. Methods A representative sample of Danish employees (n=7144, 52% females) reported levels of occupational and leisure-time physical activity in 2005. Long-term sickness absence (LTSA) spells of ≥3 consecutive weeks were retrieved from a social-transfer payment register from 2005 to 2007. Results 341 men and 620 females experienced a spell of LTSA during the period. Cox analyses adjusted for age, gender, smoking, alcohol, body mass index, chronic disease, social support from immediate superior, emotional demands, social class and occupational or leisure-time physical activity showed a decreased risk for LTSA among workers with moderate (HR 0.85, CI 0.72 to 1.01) and high (HR 0.77, CI 0.62 to 0.95) leisure-time physical activity in reference to those with low leisure-time physical activity. In contrast, an increased risk for LTSA was shown among workers with moderate (HR 1.59, CI 1.35 to 1.88) and high (HR 1.84, CI 1.55 to 2.18) occupational physical activity referencing those with low occupational physical activity. Conclusion The hypothesis was rejected. In a dose–response manner, occupational physical activity increased the risk for LTSA, while leisure-time physical activity decreased the risk for LTSA. The findings indicate opposing effects of occupational and leisure-time physical activity on global health.

9 April 2021 in European Heart Journal
Verified
Journal Article
Open access
PDF file
AHAndreas Holtermann
Andreas Holtermann
PSPeter Schnohr
Peter Schnohr
BNBørge Grønne Nordestgaard
Børge Grønne Nordestgaard
JMJacob Louis Marott
Jacob Louis Marott
Leisure time physical activity associates with reduced risk of cardiovascular disease and all-cause mortality, while these relationships for occupational physical activity are unclear. We tested the hypothesis that leisure time physical activity associates with reduced major adverse cardiovascular events (MACE) and all-cause mortality risk, while occupational physical activity associates with increased risks. We studied 104 046 women and men aged 20–100 years in the Copenhagen General Population Study with baseline measurements in 2003–2014 and median 10-year follow-up. Both leisure and occupational physical activity were based on self-report with four response categories. We observed 7913 (7.6%) MACE and 9846 (9.5%) deaths from all causes. Compared to low leisure time physical activity, multivariable adjusted (for lifestyle, health, living conditions, and socioeconomic factors) hazard ratios for MACE were 0.86 (0.78–0.96) for moderate, 0.77 (0.69–0.86) for high, and 0.85 (0.73–0.98) for very high activity; corresponding values for higher occupational physical activity were 1.04 (0.95–1.14), 1.15 (1.04–1.28), and 1.35 (1.14–1.59), respectively. For all-cause mortality, corresponding hazard ratios for higher leisure time physical activity were 0.74 (0.68–0.81), 0.59 (0.54–0.64), and 0.60 (0.52–0.69), and for higher occupational physical activity 1.06 (0.96–1.16), 1.13 (1.01–1.27), and 1.27 (1.05–1.54), respectively. Similar results were found within strata on lifestyle, health, living conditions, and socioeconomic factors, and when excluding individuals dying within the first 5 years of follow-up. Levels of the two domains of physical activity did not interact on risk of MACE (P = 0.40) or all-cause mortality (P = 0.31). Higher leisure time physical activity associates with reduced MACE and all-cause mortality risk, while higher occupational physical activity associates with increased risks, independent of each other. Risk of major adverse cardiovascular events (MACE) and all-cause mortality as a function of different categories of leisure time physical activity and occupational physical activity in individuals in the Copenhagen General Population Study.

25 November 2020 in British Journal of Sports Medicine
Verified
Journal Article
Open access
PDF file
BCBart Cillekens
Bart Cillekens
MLMatthias Lang
Matthias Lang
WMWillem van Mechelen
Willem van Mechelen
EVEvert Verhagen
Evert Verhagen
MHMaaike A Huysmans
Maaike A Huysmans
PCPieter Coenen
Pieter Coenen
Objective Physical activity (PA) has substantial benefits across a range of health outcomes. There is uncertainty about the PA-specific health effects, and in particular, the occupational domain. In this umbrella review, we synthesised available evidence on the associations between occupational PA (OPA) and health-related outcomes (including cancer, all-cause mortality and cardiovascular disease). This work informed the development of WHO’s guidelines on PA and sedentary behaviour (2020). Design Umbrella review of systematic reviews. Data source We performed a literature search in PubMed, Web of Science, Embase, CINAHL and Sportdiscuss from database inception to 2 December 2019. Eligibility criteria for selecting studies We included systematic reviews if they contained a quantitative assessment of OPA and its relationship with at least one health-related outcome. Results We summarised the evidence of 17 reviews covering 23 unique health-related outcomes. We graded most evidence as low or very low, or moderate quality. We found health benefits for those engaging in high versus low OPA for multiple cancer outcomes (including colon and prostate), ischaemic stroke, coronary heart disease and mental health (ie, mental well-being and life satisfaction). High OPA was associated with unfavourable health outcomes for all-cause mortality in men, mental ill health (ie, depression and anxiety), osteoarthritis, and sleep quality and duration. Conclusions We found favourable associations for most health-related outcomes with high OPA levels, but we also found some evidence for unfavourable associations due to high OPA levels. At this point, there is a need for better quality evidence to provide a unequivocal statement on the health effects of OPA.

29 March 2010 in Scandinavian Journal of Work, Environment & Health
Verified
Journal Article
Open access
AHAndreas Holtermann
Andreas Holtermann
OMOle Steen Mortensen
Ole Steen Mortensen
HBHermann Burr
Hermann Burr
Karen SøgaardKaren Søgaard
Karen Søgaard
FGFinn Gyntelberg
Finn Gyntelberg
PSPoul Suadicani
Poul Suadicani
Objective No previous long-term prospective studies have examined if workers with low cardiorespiratory fitness have an increased risk of cardiovascular mortality due to high physical work demands. We tested this hypothesis. Method We carried out a 30-year follow-up of the Copenhagen Male Study of 5249 employed men aged 40–59 years. We excluded from follow-up 274 men with a history of myocardial infarction, prevalent symptoms of angina pectoris, or intermittent claudication. We estimated physical fitness [maximal oxygen consumption (VO 2 Max)] using the Åstrand cycling test and determined physical work demands with two self-reported questions. Results In the Copenhagen Male Study, 587 men (11.9%) died due to ischaemic heart disease (IHD). Using men with low physical work demands as the reference group, Cox analyses – adjusted for age, blood pressure, smoking, alcohol consumption, body mass index, diabetes, and hypertension – showed that high physical work demands were associated with an increased risk of IHD mortality in the least fit [VO 2 Max range 15–26, N=892, hazard ratio (HR) 2.04, 95% confidence interval (95% CI) 1.20–3.49] and moderately fit (VO 2 Max range 27–38, N=3037, HR 1.75, 95% CI 1.24–2.46), but not among the most fit men (VO 2 Max range 39–78, N=1014, HR 1.08, 95% CI 0.52–2.17). We found a similar, although slightly weaker, relationship with respect to all-cause mortality. Conclusions The hypothesis was supported. Men with low and medium physical fitness have an increased risk of cardiovascular and all-cause mortality if exposed to high physical work demands. Ours observations suggest that, among men with high physical work demands, being physically fit protects against adverse cardiovascular effects.

20 July 2021 in International Journal of Behavioral Nutrition and Physical Activity
Verified
Journal Article
Open access
PDF file
SPStephanie Prince
Stephanie Prince
CRCharlotte Lund Rasmussen
Charlotte Lund Rasmussen
ABAviroop Biswas
Aviroop Biswas
AHAndreas Holtermann
Andreas Holtermann
TATarnbir Aulakh
Tarnbir Aulakh
PCPieter Coenen
Pieter Coenen
Background: Although it is generally accepted that physical activity reduces the risk for chronic non-communicable disease and mortality, accumulating evidence suggests that occupational physical activity (OPA) may not confer the same health benefits as leisure time physical activity (LTPA). It is also unclear if workers in high OPA jobs benefit from LTPA the same way as those in sedentary jobs. Our objective was to determine whether LTPA and leisure time sedentary behaviour (LTSB) confer the same health effects across occupations with different levels of OPA.Methods: Searches were run in Medline, Embase, PsycINFO, ProQuest Public Health and Scopus from inception to June 9, 2020. Prospective or experimental studies which examined the effects of LTPA or LTSB on all-cause and cardiovascular mortality and cardiovascular disease, musculoskeletal pain, diabetes, metabolic syndrome, arrhythmias and depression among adult workers grouped by OPA (low OPA/sitters, standers, moderate OPA/intermittent movers, high OPA/heavy labourers) were eligible. Results were synthesized using narrative syntheses and harvest plots, and certainty of evidence assessed with GRADE.Results: The review includes 38 papers. Across all outcomes, except cardiovascular mortality, metabolic syndrome and atrial fibrillation, greater LTPA was consistently protective among low OPA, but conferred less protection among moderate and high OPA. For cardiovascular mortality and metabolic syndrome, higher levels of LTPA were generally associated with similar risk reductions among all OPA groups. Few studies examined effects in standers and none examined effects of LTSB across OPA groups.Conclusions: Evidence suggests that LTPA is beneficial for all workers, but with larger risk reductions among those with low compared to high OPA jobs. This suggests that, in our attempts to improve the health of workers through LTPA, tailored interventions for different occupational groups may be required. More high-quality studies are needed to establish recommended levels of LTPA/LTSB for different OPA groups.Protocol registration: PROSPERO #CRD42020191708.

15 January 2015 in Ergonomics
Verified
Journal Article
Closed access
ISIngunn Stemland
Ingunn Stemland
JIJørgen Ingebrigtsen
Jørgen Ingebrigtsen
CCCaroline S. Christiansen
Caroline S. Christiansen
BJBente R. Jensen
Bente R. Jensen
CHChristiana Hanisch
Christiana Hanisch
AHAndreas Holtermann
Andreas Holtermann
This study examined the ability of the Acti4 software for identifying physical activity types from accelerometers during free-living with different levels of movement complexity compared with video observations. Nineteen aircraft cabin cleaners with ActiGraph GT3X+ accelerometer at the thigh and hip performed one semi-standardised and two non-standardised sessions (outside and inside aircraft) with different levels of movement complexity during working hours. The sensitivity for identifying different activity types was 75.4–99.4% for the semi-standardised session, 54.6–98.5% outside the aircraft and 49.9–90.2% inside the aircraft. The specificity was above 90% for all activities, except ‘moving’ inside the aircraft. These findings indicate that Acti4 provides good estimates of time spent in different activity types during semi-standardised conditions, and for sitting, standing and walking during non-standardised conditions with normal level of movement complexity. The Acti4 software may be a useful tool for researchers and practitioners in the field of ergonomics, occupational and public health. Practitioner Summary: Being inexpensive, small, water-resistant and without wires, the ActiGraph GT3X+ by applying the Acti4 software may be a useful tool for long-term field measurements of physical activity types for researchers and practitioners in the field of ergonomics, occupational and public health.