Chandima Karunanayake

Dr. Chandima Karunanayake

University of Sasakatchewan, Canadian Centre for Health & Safety in Agriculture
orcid

Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 January 2013 in BMC Public Health
Verified
Journal Article
Open access
PDF file
RDRoland Dyck
Roland Dyck
CKChandima Karunanayake
Chandima Karunanayake
PPPunam Pahwa
Punam Pahwa
LHLouise Hagel
Louise Hagel
JLJosh Lawson
Josh Lawson
JDJames A Dosman
James A Dosman
Although rural Canadians are reported to have higher rates of diabetes than others, little is known about the relative influence of known versus agriculture-related risk factors. The purpose of this research was to carry out a comprehensive study of prevalence, risk factors and co-morbidities of diabetes among adults in rural Saskatchewan and to determine possible differences between those living on and off farms.

16 February 2015 in Healthcare
Verified
Journal Article
Open access
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CKChandima Karunanayake
Chandima Karunanayake
DRDonna C. Rennie
Donna C. Rennie
LHLouise Hagel
Louise Hagel
JLJosh Lawson
Josh Lawson
BJBonnie L. Janzen
Bonnie L. Janzen
TGThe Saskatchewan Rural Health Study Group
The Saskatchewan Rural Health Study Group
The role of place has emerged as an important factor in determining people’s health experiences. Rural populations experience an excess in mortality and morbidity compared to those in urban settings. One of the factors thought to contribute to this rural-urban health disparity is access to healthcare. The objective of this analysis was to examine access to specialized medical care services and several possible determinants of access to services in a distinctly rural population in Canada. In winter 2010, we conducted a baseline mail survey of 11,982 households located in rural Saskatchewan, Canada. We obtained 4620 completed household surveys. A key informant for each household responded to questions about access to medical specialists and the exact distance traveled to these services. Correlates of interest included the location of the residence within the province and within each household, socioeconomic status, household smoking status, median age of household residents, number of non-respiratory chronic conditions and number of current respiratory conditions. Analyses were conducted using log binomial regression for the outcome of interest. The overall response rate was 52%. Of households who required a visit to a medical specialist in the past 12 months, 23% reported having difficulty accessing specialist care. The magnitude of risk for encountering difficulty accessing medical specialist care services increased with the greatest distance categories. Accessing specialist care professionals by rural residents was particularly difficult for persons with current respiratory conditions.

1 August 2012 in BMC Research Notes
Verified
Journal Article
Open access
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PPPunam Pahwa
Punam Pahwa
CKChandima Karunanayake
Chandima Karunanayake
LHLouise Hagel
Louise Hagel
BJBonnie L. Janzen
Bonnie L. Janzen
WPWilliam Pickett
William Pickett
JDJames A Dosman
James A Dosman
Respiratory disease can impose a significant burden on the health of rural populations. The Saskatchewan Rural Health Study (SRHS) is a new large prospective cohort study of ages 6 and over currently being conducted in farming and non-farming communities to evaluate potential health determinants associated with respiratory outcomes in rural populations. In this article, we describe the rationale and methodology for the adult component.

27 February 2009 in BMC Cancer
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Journal Article
Open access
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HMHelen H McDuffie
Helen H McDuffie
PPPunam Pahwa
Punam Pahwa
CKChandima Karunanayake
Chandima Karunanayake
JSJohn Spinelli
John Spinelli
JDJames A Dosman
James A Dosman
Background: A positive family history of chronic diseases including cancer can be used as an index of genetic and shared environmental influences. The tumours studied have several putative risk factors in common including occupational exposure to certain pesticides and a positive family history of cancer.Methods: We conducted population-based studies of Hodgkin lymphoma (HL), Multiple Myeloma (MM), non-Hodgkin's Lymphoma (NHL), and Soft Tissue Sarcoma (STS) among male incident case and control subjects in six Canadian provinces. The postal questionnaire was used to collect personal demographic data, a medical history, a lifetime occupational history, smoking pattern, and the information on family history of cancer. The family history of cancer was restricted to first degree relatives and included relationship to the index subjects and the types of tumours diagnosed among relatives. The information was collected on 1528 cases (HL (n = 316), MM (n = 342), NHL (n = 513), STS (n = 357)) and 1506 age ± 2 years and province of residence matched control subjects. Conditional logistic regression analyses adjusted for the matching variables were conducted.Results: We found that most families were cancer free, and a minority included two or more affected relatives. HL [(ORadj(95% CI)1.79 (1.33, 2.42)], MM(1.38(1.07, 1.78)), NHL(1.43 (1.15, 1.77)), and STS cases(1.30(1.00, 1.68))had higher incidence of cancer if any first degree relative was affected with cancer compared to control families. Constructing mutually exclusive categories combining "family history of cancer" (yes, no) and "pesticide exposure ≥10 hours per year" (yes, no) indicated that a positive family history was important for HL(2.25(1.61, 3.15)), and for the combination of the two exposures increased risk for MM(1.69(1.14,2.51)). Also, a positive family history of cancer both with(1.72 (1.21, 2.45))and without pesticide exposure(1.43(1.12, 1.83))increased risk of NHL.Conclusion: HL, MM, NHL, and STS cases had higher incidence of cancer if any first degree relative affected with cancer compared to control families. A positive family history of cancer and/or shared environmental exposure to agricultural chemicals play an important role in the development of cancer.

16 May 2015 in BMC Research Notes
Verified
Journal Article
Open access
PDF file
PPPunam Pahwa
Punam Pahwa
SASylvia Abonyi
Sylvia Abonyi
CKChandima Karunanayake
Chandima Karunanayake
DRDonna C. Rennie
Donna C. Rennie
BJBonnie L. Janzen
Bonnie L. Janzen
JDJames A Dosman
James A Dosman
To date, determinants of respiratory health in First Nations people living on reserves and means of addressing and redressing those determinants have not been well established. Hence the Saskatchewan First Nations Lung Health Project (FNLHP) is a new prospective cohort study of aboriginal people being conducted in two First Nations reserves to evaluate potential health determinants associated with respiratory outcomes. Using the population health framework (PHF) of Health Canada, instruments designed with the communities, joint ownership of data, and based on the 4-phase concept of the First Nations Regional Longitudinal Health Survey, the project aims to evaluate individual factors, contextual factors, and principal covariates on respiratory outcomes. The objective of this report is to clearly describe the methodology of (i) the baseline survey that consists of two components, an interviewer-administered questionnaire and clinical assessment; and (ii) potential intervention programs; and present descriptive results of the baseline data of longitudinal FNLHP. The study is being conducted over 5 years (2012–2017) in two phases, baseline and longitudinal. Baseline survey has been completed and consisted of (i) an interviewer-administered questionnaire-based evaluation of individual and contextual factors of importance to respiratory health (with special focus on chronic bronchitis, chronic obstructive pulmonary disease, asthma and obstructive sleep apnea), and (ii) clinical lung function and allergy tests with the consent of study participants. The address-redress phase consists of potential intervention programs and is currently being rolled out to address-at community level (via green light program and environmental study), and redress-at policy level (via obesity reduction and improved diagnosis and treatment of obstructive sleep apnea) the issues that have been identified by the baseline data. Interviewer-administered surveys were conducted in 2012–2013 and collected data on 874 individuals living in 406 households from two reserve communities located in Saskatchewan, Canada. Four hundred and forty six (51%) females and 428 (49%) males participated in the FNLHP. The information from this project will assist in addressing and redressing many of the issues involved including the provision of adequate housing, health lifestyle practices, and in planning for health service delivery.

14 January 2019 in Canadian Respiratory Journal
Verified
Journal Article
Open access
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CSCatherine M. Spagnuolo
Catherine M. Spagnuolo
MMMichael McIsaac
Michael McIsaac
JDJames Dosman
James Dosman
CKChandima Karunanayake
Chandima Karunanayake
PPPunam Pahwa
Punam Pahwa
WPWilliam Pickett
William Pickett
Obstructive sleep apnea (OSA) is the most common sleep-disordered breathing condition. Patients with OSA symptoms are often not diagnosed clinically, which is a concern, given the health and safety risks associated with unmanaged OSA. The availability of fewer practicing medical specialists combined with longer travel distances to access health care services results in barriers to diagnosis and treatment in rural communities. This study aimed to (1) determine whether the proportion of adults reporting OSA symptoms in the absence of a sleep apnea diagnosis in rural populations varied by travel distance to specialist medical care and (2) assess whether any distance-related patterns were attributable to differences in the frequency of diagnosis among adults who likely required this specialist medical care. We used a cross-sectional epidemiologic study design, augmented by analysis of follow-up survey data. Our study base included adults who completed a 2010 baseline questionnaire for the Saskatchewan Rural Health Study. Follow-up occurred until 2015. 6525 adults from 3731 households constituted our sample. Statistical models used log-binomial regression. Rural adults who reported the largest travel distances (≥250 km) to specialist medical care were 1.17 (95% CI: 1.07, 1.29) times more likely to report OSA symptoms in the absence of a sleep apnea diagnosis than those who reported the smallest (<100 km; referent) distances. However, the proportion of sleep apnea diagnoses was low and unaffected by reported travel distance among adults who likely required this specialist medical care. Our findings suggest factors other than travel distance may be contributing to the low sleep apnea diagnostic rate. This remains important as undiagnosed and untreated OSA has serious implications on the health of people and populations, but effective treatments are available. Health care access barriers to the diagnosis and treatment of OSA require evaluation to inform health care planning and delivery.