Research disclosed since the demonstration of the first examples of primary amine-thiourea organocatalysis in 2006 has shown that primary amine-based thioureas can successfully catalyze a diverse variety of highly enantioselective transformations providing a wide range of versatile organic compounds. Recent remarkable progress with these chiral catalysts is summarized in this review.

This review presents non-heme iron catalyzed epoxidations and aziridinations of terminal alkenes with respect to atom economy and sustainability.

Indolo[3,2-c]quinolines are pharmacologically attractive class of heterocyclic compounds. The method of their synthesis, based on transformation of furfural, which is a large-scale product of treatment of biomass including agricultural and forestry wastes, has been developed. This method was utilized for the total synthesis of antimalarial alkaloid isocryptolepine and its derivatives.

Approaches towards fluorothiophenes, perfluoroalkyl­thiophenes, perfluoroarylthiophenes and their benzo-analogues are reviewed. The literature up to 2010 is highlighted. 1 Introduction 2 Synthesis of Fluorothiophenes 2.1 Functionalization of the Thiophene Ring 2.2 Heterocyclization 3 Synthesis of Perfluoroalkylthiophenes 3.1 Functionalization of the Thiophene Ring 3.2 Heterocyclization and Cycloaddition 4 Synthesis of Fluorobenzothiophenes 5 Synthesis of Perfluoroalkylbenzothiophenes 6 Synthesis of Perfluoroarylthiophenes 6.1 Organometallic Synthesis 6.2 Cross-Coupling 6.3 Heterocyclization 7 Synthesis of Perfluoroarylbenzothiophenes 8 Synthesis of Benzothiophenes with a Perfluorinated Carbocycle 9 Conclusions