Kirsten St. St. George

Dr. Kirsten St. St. George

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Research Focus & Metrics

Academic Career Length

28Years (1999-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 April 2020 in mBio
Verified
Journal Article
Open access
PDF file
RPRobin Patel
Robin Patel
EBEsther Babady
Esther Babady
ETElitza S. Theel
Elitza S. Theel
GSGregory A. Storch
Gregory A. Storch
BPBenjamin A Pinsky
Benjamin A Pinsky
SBStefano Bertuzzi
Stefano Bertuzzi

1 May 2021 in Cell
Verified
Journal Article
Closed access
TATara Alpert
Tara Alpert
ABAnderson F. Brito
Anderson F. Brito
ELErica Lasek-Nesselquist
Erica Lasek-Nesselquist
JRJessica Rothman
Jessica Rothman
AVAndrew L. Valesano
Andrew L. Valesano
NGNathan D. Grubaugh
Nathan D. Grubaugh

1 June 2016 in Journal of Clinical Virology
Verified
Journal Article
Closed access
JMJana McGinnis
Jana McGinnis
JLJennifer Laplante
Jennifer Laplante
MSMatthew Shudt
Matthew Shudt
KGKirsten St. St. George
Kirsten St. St. George

1 October 2018 in Journal of Clinical Microbiology
Verified
Journal Article
Closed access
PDF file
DGDaniel A Green
Daniel A Green
KGKirsten St. St. George
Kirsten St. St. George
Rapid antigen tests for influenza, here referred to as rapid influenza diagnostic tests (RIDTs), have been widely used for the diagnosis of influenza since their introduction in the 1990s due to their ease of use, rapid results, and suitability for point of care (POC) testing. However, issues related to the diagnostic sensitivity of these assays have been known for decades, and these issues gained greater attention following reports of their poor performance during the 2009 influenza A(H1N1) pandemic.

23 July 2020 in Journal of Clinical Microbiology
Verified
Journal Article
Closed access
PDF file
SMStephanie L. Mitchell
Stephanie L. Mitchell
KGKirsten St. St. George
Kirsten St. St. George
DRDaniel D. Rhoads
Daniel D. Rhoads
SBSusan M. Butler-Wu
Susan M. Butler-Wu
VDVaishali Dharmarha
Vaishali Dharmarha
MMMelissa B. Miller
Melissa B. Miller
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has brought a new wave of challenges to health care, particularly in the area of rapid diagnostic test development and implementation. The diagnosis of acute coronavirus disease 2019 (COVID-19) is critically dependent on the detection of SARS-CoV-2 RNA from clinical specimens (e.g., nasopharyngeal swabs). While laboratory-developed testing for SARS-CoV-2 is an essential component of diagnostic testing for this virus, the majority of clinical microbiology laboratories are dependent on commercially available SARS-CoV-2 molecular assays. In contrast to assays approved or cleared by the U.S. Food and Drug Administration (FDA) for in vitro diagnostic use, assays for the detection of SARS-CoV-2 nucleic acids have emergency use authorization (EUA) from the FDA. Outside of highly specialized academic and commercial laboratory settings, clinical microbiology laboratories are likely unfamiliar with the EUA classification, and thus, assay verification can be daunting. Further compounding anxiety for laboratories are major issues with the supply chain that are dramatically affecting the availability of test reagents and requiring laboratories to implement multiple commercial EUA tests. Here, we describe guidance for the verification of assays with EUA for the detection of SARS-CoV-2 nucleic acid from clinical specimens.

20 April 2021 in Journal of Clinical Microbiology
Verified
Journal Article
Closed access
SGSara B. Griesemer
Sara B. Griesemer
GSGreta Van Slyke
Greta Van Slyke
DEDylan Ehrbar
Dylan Ehrbar
KSKlemen Strle
Klemen Strle
TYTugba Yildirim
Tugba Yildirim
KGKirsten St. St. George
Kirsten St. St. George
Identifying SARS-CoV-2 infections through aggressive diagnostic testing remains critical to tracking and curbing the spread of the COVID-19 pandemic. Collection of nasopharyngeal swabs (NPS), the preferred sample type for SARS-CoV-2 detection, has become difficult due to the dramatic increase in testing and consequent supply strain.