Eleftheria Giannouli

Dr. Eleftheria Giannouli

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Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2016 in BioMed Research International
Verified
Journal Article
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EGEleftheria Giannouli
Eleftheria Giannouli
Otmar BockOtmar Bock
Otmar Bock
Sabato MelloneSabato Mellone
Sabato Mellone
WZWiebren Zijlstra
Wiebren Zijlstra
Background. Outcomes of laboratory-based tests for mobility are often used to infer about older adults’ performance in real life; however, it is unclear whether such association exists. We hypothesized that mobility capacity, as measured in the laboratory, and mobility performance, as measured in real life, would be poorly linked.Methods. The sample consisted of 84 older adults (72.5±5.9years). Capacity was assessed via the iTUG and standard gait parameters (stride length, stride velocity, and cadence). Performance was assessed in real life over a period of6.95±1.99days using smartphone technology to calculate following parameters: active and gait time, number of steps, life-space, mean action-range, and maximum action-range. Correlation analyses and stepwise multiple regression analyses were applied.Results. All laboratory measures demonstrated significant associations with the real-life measures (betweenr=.229andr=.461). The multiple regression analyses indicated that the laboratory measures accounted for a significant but very low proportion of variance (between 5% and 21%) in real-life measures.Conclusion. In older adults without mobility impairments, capacity-related measures of mobility bear little significance for predicting real-life performance. Hence, other factors play a role in how older people manage their daily-life mobility. This should be considered for diagnosis and treatment of mobility deficits in older people.

24 July 2019 in International Journal of Health Geographics
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MFMichelle Fillekes
Michelle Fillekes
EGEleftheria Giannouli
Eleftheria Giannouli
EKEun-Kyeong Kim
Eun-Kyeong Kim
WZWiebren Zijlstra
Wiebren Zijlstra
RWRobert Weibel
Robert Weibel
GPS tracking is increasingly used in health and aging research to objectively and unobtrusively assess individuals’ daily-life mobility. However, mobility is a complex concept and its thorough description based on GPS-derived mobility indicators remains challenging. With the aim of reflecting the breadth of aspects incorporated in daily mobility, we propose a conceptual framework to classify GPS-derived mobility indicators based on their characteristic and analytical properties for application in health and aging research. In order to demonstrate how the classification framework can be applied, existing mobility indicators as used in existing studies are classified according to the proposed framework. Then, we propose and compute a set of selected mobility indicators based on real-life GPS data of 95 older adults that reflects diverse aspects of individuals’ daily mobility. To explore latent dimensions that underlie the mobility indicators, we conduct a factor analysis. The proposed framework enables a conceptual classification of mobility indicators based on the characteristic and analytical aspects they reflect. Characteristic aspects inform about the content of the mobility indicator and comprise categories related to space, time, movement scope, and attribute. Analytical aspects inform how a mobility indicator is aggregated with respect to temporal scale and statistical property. The proposed categories complement existing studies that often underrepresent mobility indicators involving timing, temporal distributions, and stop-move segmentations of movements. The factor analysis uncovers the following six dimensions required to obtain a comprehensive view of an older adult’s daily mobility: extent of life space, quantity of out-of-home activities, time spent in active transport modes, stability of life space, elongation of life space, and timing of mobility. This research advocates incorporating GPS-based mobility indicators that reflect the multi-dimensional nature of individuals’ daily mobility in future health- and aging-related research. This will foster a better understanding of what aspects of mobility are key to healthy aging.

1 November 2019 in Experimental Gerontology
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MMMareike Morat
Mareike Morat
JBJulia Bakker
Julia Bakker
VHVerena Hammes
Verena Hammes
Tobias MoratTobias Morat
Tobias Morat
EGEleftheria Giannouli
Eleftheria Giannouli
LDLars Donath
Lars Donath

3 November 2019 in European Review of Aging and Physical Activity
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Journal Article
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EGEleftheria Giannouli
Eleftheria Giannouli
MFMichelle Pasquale Fillekes
Michelle Pasquale Fillekes
Sabato MelloneSabato Mellone
Sabato Mellone
RWRobert Weibel
Robert Weibel
OBOtmar Bock
Otmar Bock
WZWiebren Zijlstra
Wiebren Zijlstra
Background: Reduced mobility is associated with a plethora of adverse outcomes. To support older adults in maintaining their independence, it first is important to have deeper knowledge of factors that impact on their mobility. Based on a framework that encompasses demographical, environmental, physical, cognitive, psychological and social domains, this study explores predictors of different aspects of real-life mobility in community-dwelling older adults.Methods: Data were obtained in two study waves with a total sample ofn = 154. Real-life mobility (physical activity-based mobility and life-space mobility) was assessed over one week using smartphones. Active and gait time and number of steps were calculated from inertial sensor data, and life-space area, total distance, and action range were calculated from GPS data. Demographic measures included age, gender and education. Physical functioning was assessed based on measures of cardiovascular fitness, leg and handgrip strength, balance and gait function; cognitive functioning was assessed based on measures of attention and executive function. Psychological and social assessments included measures of self-efficacy, depression, rigidity, arousal, and loneliness, sociableness, perceived help availability, perceived ageism and social networks. Maximum temperature was used to assess weather conditions on monitoring days.Results: Multiple regression analyses indicated just physical and psychological measures accounted for significant but rather low proportions of variance (5–30%) in real-life mobility. Strength measures were retained in most of the regression models. Cognitive and social measures did not remain as significant predictors in any of the models.Conclusions: In older adults without mobility limitations, real-life mobility was associated primarily with measures of physical functioning. Psychological functioning also seemed to play a role for real-life mobility, though the associations were more pronounced for physical activity-based mobility than life-space mobility. Further factors should be assessed in order to achieve more conclusive results about predictors of real-life mobility in community-dwelling older adults.

20 June 2017 in European Journal of Ageing
Verified
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EGEleftheria Giannouli
Eleftheria Giannouli
OBOtmar Bock
Otmar Bock
WZWiebren Zijlstra
Wiebren Zijlstra

29 November 2021 in Frontiers in Aging Neuroscience
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Journal Article
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PAPatrizia Altorfer
Patrizia Altorfer
MAManuela Adcock
Manuela Adcock
EBEling D. de Bruin
Eling D. de Bruin
FGFlorian Graf
Florian Graf
EGEleftheria Giannouli
Eleftheria Giannouli
Objective: The aim of this pilot randomized clinical trial was to test the feasibility and efficacy of an exergame-based cognitive-motor training program in geriatric inpatients.Methods: The study participants were randomly allocated to either the exergame intervention group or the control group. The control group received the standard rehabilitation treatment offered in the clinic. In addition to the standard rehabilitation program, the intervention group conducted supervised exergame training on 5 days per week using the Dividat Senso, an exergame system specifically designed for older adults. The primary outcome was feasibility, as measured by e.g., adherence rate, attrition rate, occurrence of adverse events, System Usability Scale (SUS) and NASA-TLX score. Secondary outcomes included measures of physical and cognitive functioning such as comfortable walking speed, maximal walking speed, dual task walking speed, Short Physical Performance Battery (SPPB), Timed Up and Go test (TUG), Color-Word Interference test (D-KEFS), Trail Making test A and B (TMT), Go/No-Go test and Step Reaction Time test (SRTT). All secondary outcome measures were assessed pre- and post-intervention.Results: Thirty-nine persons were included in the study. Average adherence rate was 99%, there were no intervention-related dropouts and no adverse events. The mean System Usability Scale (SUS) score was 83.6 and the mean NASA-TLX score 45.5. Significant time-group interaction effects were found for the dual task walking speed, the Go/No-Go test and Step Reaction Time test (SRTT).Conclusion: Exergaming is a feasible, safe and effective cognitive-motor training approach in inpatient rehabilitation of geriatric patients. Incorporating exergaming in the rehabilitation program of geriatric patients offers potential to reduce fall risk factors and to increase patients’ exercise motivation and rehabilitation success.