Po-Hsiang Chang is committed to basic research on the adsorption and removal of environmental pollutants in water by the natural nanominerals and synthetic materials such as MOF materials. His study is focused on the cation exchange of interfaces, molecular adsorption kinetics and thermodynamics, molecular simulation characterization, and molecular adsorption mechanisms. A new protection mechanism for structural intercalation to prevent organic molecules from desorbing and causing secondary pollution was proposed; the removal rate of nanominerals and related adsorption parameters were analyzed, and the understanding of the interaction mechanism between nanominerals and organic molecules was analyzed from a macroscopic perspective. Not only does his study discuss the adsorption amounts and adsorption types, but it provides an in-depth understanding of the ultra-microscopic level of mineral fine structure and organic functional groups. It specifically reveals the process of natural nano-minerals affecting the fate, migration, and transformation of organic pollutants in the surface environment and provides technical support and method selection for the development of low-cost and high-efficiency pollutant prevention and control projects for environmental remediation projects. The results have a very theoretically guided role and possess value for potential applications.