The coupled and coordinated development of urban resilience and new urbanization is an important guarantee for the realization of urban security and sustainable development. This paper first constructs an evaluation index of urban resilience and new urbanization and uses the entropy method to clarify the weights. Second, the coupling coordination degree model is used to measure the spatiotemporal differentiation characteristics of the coupling coordinated development of urban resilience and new urbanization in the Yangtze River Economic Belt from 2005 to 2019. The key influencing factors of the coupling coordination are analyzed using geodetectors. The results show the following. (1) The urban resilience of the Yangtze River Economic Belt has continued to improve, showing a stepwise distribution pattern of “high in the east and low in the west” in space. The overall development of new urbanization is at a medium–high level, with high levels concentrated in the eastern coastal cities. (2) The degree of spatial coupling and coordination between urban resilience and new urbanization is increasing year by year, and there is significant spatial heterogeneity, showing the pattern of “high in the east and low in the west, high in the center and low in the surrounding areas”, and the type of lag is mostly urban resilience lag in new urbanization. (3) Endogenous power, external power, government power and market power interact to jointly promote the development of coupling coordination. The comprehensive effect of government power and other driving forces is the key mechanism for improving spatial coupling coordination.

Promoting the development of collaborative innovation networks is crucial for cities to achieve sustainable innovation. Hangzhou was selected as a case study. Based on the cooperation patent data from 2000 to 2017, we examined the scale problem, calculated the topology, and analyzed the coordination mechanisms and spatial characteristics of the topology structure. The results show that in terms of the development trend, collaborative innovation is an important pathway for innovation, and multi-subject collaborative innovation is necessary. Collaborative innovation occurs between enterprises and between enterprises and universities. With regards to topological structure, we found “Zhejiang University as a center, other universities as cores”, with the characteristics of diffusion development and fragmentation. In terms of spatial structure, we observed a networked spatial organization model with multiple centers, such as universities and industrial parks. A circle with a radius of five kilometers around a university was found to be an area of highly concentrated innovation subjects that are synergistically associated with universities. On this basis, the laws are summarized and suggestions are provided to support the research and practice of urban innovation spatial planning in China.