Antonia Tricoupoulou

Dr. Antonia Tricoupoulou

President Hellenic Health Foundation
+1

Research Focus & Metrics

Academic Career Length

31Years (1996-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
26 June 2003 in New England Journal of Medicine
Verified
Journal Article
Closed access
PDF file
Antonia TricoupoulouAntonia Tricoupoulou
Antonia Tricoupoulou
TCTina Costacou
Tina Costacou
CBChristina Bamia
Christina Bamia
DTDimitrios Trichopoulos
Dimitrios Trichopoulos
Adherence to a Mediterranean diet may improve longevity, but relevant data are limited.

8 April 2005 in BMJ
Verified
Journal Article
Open access
PDF file
Antonia TricoupoulouAntonia Tricoupoulou
Antonia Tricoupoulou
POPhilippos Orfanos
Philippos Orfanos
TNTeresa Norat
Teresa Norat
BBBas Bueno-De-Mesquita
Bas Bueno-De-Mesquita
MOMarga C Ocké
Marga C Ocké
DTDimitrios Trichopoulos
Dimitrios Trichopoulos
Objective To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. Design Multicentre, prospective cohort study. Setting Nine European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Sweden, United Kingdom). Participants 74 607 men and women, aged 60 or more, without coronary heart disease, stroke, or cancer at enrolment and with complete information about dietary intake and potentially confounding variables. Main outcome measures Extent of adherence to a modified Mediterranean diet using a scoring system on a 10 point scale, and death from any cause by time of occurrence, modelled through Cox regression. Results An increase in the modified Mediterranean diet score was associated with lower overall mortality, a two unit increment corresponding to a statistically significant reduction of 8% (95% confidence interval 3% to 12%). No statistically significant evidence of heterogeneity was found among countries in the association of the score with overall mortality even though the association was stronger in Greece and Spain. When dietary exposures were calibrated across countries, the reduction in mortality was 7% (1% to 12%). Conclusion The Mediterranean diet, modified so as to apply across Europe, was associated with increased survival among older people.

24 July 2014 in BMC Medicine
Verified
Journal Article
Open access
PDF file
Antonia TricoupoulouAntonia Tricoupoulou
Antonia Tricoupoulou
MMMiguel A. Martinez-Gonzalez
Miguel A. Martinez-Gonzalez
TTTammy Tong
Tammy Tong
NFNita G. Forouhi
Nita G. Forouhi
Shweta KhandelwalShweta Khandelwal
Shweta Khandelwal
MLMichel De Lorgeril
Michel De Lorgeril
The Mediterranean diet has been linked to a number of health benefits, including reduced mortality risk and lower incidence of cardiovascular disease. Definitions of the Mediterranean diet vary across some settings, and scores are increasingly being employed to define Mediterranean diet adherence in epidemiological studies. Some components of the Mediterranean diet overlap with other healthy dietary patterns, whereas other aspects are unique to the Mediterranean diet. In this forum article, we asked clinicians and researchers with an interest in the effect of diet on health to describe what constitutes a Mediterranean diet in different geographical settings, and how we can study the health benefits of this dietary pattern.

1 October 2004 in The American Journal of Clinical Nutrition
Verified
Journal Article
Open access
PDF file
TPTheodora Psaltopoulou
Theodora Psaltopoulou
ANAndroniki Naska
Androniki Naska
POPhilippos Orfanos
Philippos Orfanos
DTDimitrios Trichopoulos
Dimitrios Trichopoulos
TMTheodoros Mountokalakis
Theodoros Mountokalakis
Antonia TricoupoulouAntonia Tricoupoulou
Antonia Tricoupoulou
Background: Diet has been reported to influence arterial blood pressure, and evidence indicates that the Mediterranean diet reduces cardiovascular mortality. Objective: The objective was to examine whether the Mediterranean diet, as an entity, and olive oil, in particular, reduce arterial blood pressure. Design: Arterial blood pressure and several sociodemographic, anthropometric, dietary, physical activity, and clinical variables were recorded at enrollment among participants in the Greek arm of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Of these participants, 20 343 had never received a diagnosis of hypertension and were included in an analysis in which systolic and diastolic blood pressure were regressed on the indicated possible predictors, including a 10-point score that reflects adherence to the Mediterranean diet and, alternatively, the score's individual components and olive oil. Results: The Mediterranean diet score was significantly inversely associated with both systolic and diastolic blood pressure. Intakes of olive oil, vegetables, and fruit were significantly inversely associated with both systolic and diastolic blood pressure, whereas cereals, meat and meat products, and ethanol intake were positively associated with arterial blood pressure. Mutual adjustment between olive oil and vegetables, which are frequently consumed together, indicated that olive oil has the dominant beneficial effect on arterial blood pressure in this population. Conclusions: Adherence to the Mediterranean diet is inversely associated with arterial blood pressure, even though a beneficial component of the Mediterranean diet score—cereal intake—is positively associated with arterial blood pressure. Olive oil intake, per se, is inversely associated with both systolic and diastolic blood pressure.

Lluis Serra-MajemLluis Serra-Majem
Lluis Serra-Majem
LTLaura Tomaino
Laura Tomaino
SDSandro Dernini
Sandro Dernini
EBElliot Berry
Elliot Berry
DLDenis Lairon
Denis Lairon
Antonia TricoupoulouAntonia Tricoupoulou
Antonia Tricoupoulou
Background: Nowadays the food production, supply and consumption chain represent a major cause of ecological pressure on the natural environment, and diet links worldwide human health with environmental sustainability. Food policy, dietary guidelines and food security strategies need to evolve from the limited historical approach, mainly focused on nutrients and health, to a new one considering the environmental, socio-economic and cultural impact—and thus the sustainability—of diets. Objective: To present an updated version of the Mediterranean Diet Pyramid (MDP) to reflect multiple environmental concerns. Methods: We performed a revision and restructuring of the MDP to incorporate more recent findings on the sustainability and environmental impact of the Mediterranean Diet pattern, as well as its associations with nutrition and health. For each level of the MDP we provided a third dimension featuring the corresponding environmental aspects related to it. Conclusions: The new environmental dimension of the MDP enhances food intake recommendations addressing both health and environmental issues. Compared to the previous 2011 version, it emphasizes more strongly a lower consumption of red meat and bovine dairy products, and a higher consumption of legumes and locally grown eco-friendly plant foods as much as possible.

7 March 2013 in BMC Medicine
Verified
Journal Article
Open access
PDF file
Sabine ROHRMANNSabine ROHRMANN
Sabine ROHRMANN
KOKim Overvad
Kim Overvad
HBH Bas Bueno-De-Mesquita
H Bas Bueno-De-Mesquita
Marianne Uhre JakobsenMarianne Uhre Jakobsen
Marianne Uhre Jakobsen
RERikke Egeberg
Rikke Egeberg
JLJakob Linseisen
Jakob Linseisen
Recently, some US cohorts have shown a moderate association between red and processed meat consumption and mortality supporting the results of previous studies among vegetarians. The aim of this study was to examine the association of red meat, processed meat, and poultry consumption with the risk of early death in the European Prospective Investigation into Cancer and Nutrition (EPIC). Included in the analysis were 448,568 men and women without prevalent cancer, stroke, or myocardial infarction, and with complete information on diet, smoking, physical activity and body mass index, who were between 35 and 69 years old at baseline. Cox proportional hazards regression was used to examine the association of meat consumption with all-cause and cause-specific mortality. As of June 2009, 26,344 deaths were observed. After multivariate adjustment, a high consumption of red meat was related to higher all-cause mortality (hazard ratio (HR) = 1.14, 95% confidence interval (CI) 1.01 to 1.28, 160+ versus 10 to 19.9 g/day), and the association was stronger for processed meat (HR = 1.44, 95% CI 1.24 to 1.66, 160+ versus 10 to 19.9 g/day). After correction for measurement error, higher all-cause mortality remained significant only for processed meat (HR = 1.18, 95% CI 1.11 to 1.25, per 50 g/d). We estimated that 3.3% (95% CI 1.5% to 5.0%) of deaths could be prevented if all participants had a processed meat consumption of less than 20 g/day. Significant associations with processed meat intake were observed for cardiovascular diseases, cancer, and 'other causes of death'. The consumption of poultry was not related to all-cause mortality. The results of our analysis support a moderate positive association between processed meat consumption and mortality, in particular due to cardiovascular diseases, but also to cancer.